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2017 1
2019 4
2020 6
2021 1
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Role of changes in SARS-CoV-2 spike protein in the interaction with the human ACE2 receptor: An in silico analysis.
Ortega JT, Serrano ML, Pujol FH, Rangel HR. Ortega JT, et al. EXCLI J. 2020 Mar 18;19:410-417. doi: 10.17179/excli2020-1167. eCollection 2020. EXCLI J. 2020. PMID: 32210742 Free PMC article.
Unrevealing sequence and structural features of novel coronavirus using in silico approaches: The main protease as molecular target.
Ortega JT, Serrano ML, Pujol FH, Rangel HR. Ortega JT, et al. EXCLI J. 2020 Mar 17;19:400-409. doi: 10.17179/excli2020-1189. eCollection 2020. EXCLI J. 2020. PMID: 32210741 Free PMC article.
Class A G Protein-Coupled Receptor Antagonist Famotidine as a Therapeutic Alternative Against SARS-CoV2: An In Silico Analysis.
Ortega JT, Serrano ML, Jastrzebska B. Ortega JT, et al. Biomolecules. 2020 Jun 24;10(6):954. doi: 10.3390/biom10060954. Biomolecules. 2020. PMID: 32599963 Free PMC article.
The Retinoid and Non-Retinoid Ligands of the Rod Visual G Protein-Coupled Receptor.
Ortega JT, Jastrzebska B. Ortega JT, et al. Int J Mol Sci. 2019 Dec 10;20(24):6218. doi: 10.3390/ijms20246218. Int J Mol Sci. 2019. PMID: 31835521 Free PMC article. Review.
Specificity of the chromophore-binding site in human cone opsins.
Katayama K, Gulati S, Ortega JT, Alexander NS, Sun W, Shenouda MM, Palczewski K, Jastrzebska B. Katayama K, et al. Among authors: ortega jt. J Biol Chem. 2019 Apr 12;294(15):6082-6093. doi: 10.1074/jbc.RA119.007587. Epub 2019 Feb 15. J Biol Chem. 2019. PMID: 30770468 Free PMC article.
Understanding Severe Acute Respiratory Syndrome Coronavirus 2 Replication to Design Efficient Drug Combination Therapies.
Ortega JT, Zambrano JL, Jastrzebska B, Liprandi F, Rangel HR, Pujol FH. Ortega JT, et al. Intervirology. 2020;63(1-6):2-9. doi: 10.1159/000512141. Epub 2020 Oct 23. Intervirology. 2020. PMID: 33099545 Free PMC article. Review.
Retinoid analogs and polyphenols as potential therapeutics for age-related macular degeneration.
Parmar T, Ortega JT, Jastrzebska B. Parmar T, et al. Among authors: ortega jt. Exp Biol Med (Maywood). 2020 Nov;245(17):1615-1625. doi: 10.1177/1535370220926938. Epub 2020 May 21. Exp Biol Med (Maywood). 2020. PMID: 32438835
Protective Effects of Flavonoids in Acute Models of Light-Induced Retinal Degeneration.
Ortega JT, Parmar T, Golczak M, Jastrzebska B. Ortega JT, et al. Mol Pharmacol. 2021 Jan;99(1):60-77. doi: 10.1124/molpharm.120.000072. Epub 2020 Nov 5. Mol Pharmacol. 2021. PMID: 33154094
Flavonoids enhance rod opsin stability, folding, and self-association by directly binding to ligand-free opsin and modulating its conformation.
Ortega JT, Parmar T, Jastrzebska B. Ortega JT, et al. J Biol Chem. 2019 May 17;294(20):8101-8122. doi: 10.1074/jbc.RA119.007808. Epub 2019 Apr 3. J Biol Chem. 2019. PMID: 30944172 Free PMC article.
Antiviral activity of flavonoids present in aerial parts of Marcetia taxifolia against Hepatitis B virus, Poliovirus, and Herpes Simplex Virus in vitro.
Ortega JT, Serrano ML, Suárez AI, Baptista J, Pujol FH, Cavallaro LV, Campos HR, Rangel HR. Ortega JT, et al. EXCLI J. 2019 Nov 5;18:1037-1048. doi: 10.17179/excli2019-1837. eCollection 2019. EXCLI J. 2019. PMID: 31762727 Free PMC article.
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