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Characteristics and predictors of death among 4035 consecutively hospitalized patients with COVID-19 in Spain.
Berenguer J, Ryan P, Rodríguez-Baño J, Jarrín I, Carratalà J, Pachón J, Yllescas M, Arriba JR; COVID-19@Spain Study Group; Fundación SEIMC-GESIDA; Hospital General Universitario Gregorio Marañón; Hospital Universitario La Paz; Hospital Infanta Leonor; Complejo Hospitalario Virgen de la Salud; Hospital Universitario Rafael Méndez; Hospital Universitario de Cruces; Hospital de Melilla; Hospital San Eloy de Barakaldo; Hospital Universitario Central de Asturias; Hospital General Universitario de Alicante; Hospital Virgen de la Victoria; Hospital Universitario Puerto Real; EOXI Pontevedra e Salnés; Hospital de Figueres; Hospital Sant Jaume de Calella; Hospital del Mar; Hospital Virgen de la Arrixaca; Hospital de Can Misses; Hospital de Sagunto; Hospital Clínico San Cecilio; Hospital Universitario Príncipe de Asturias; Parc Sanitari Sant Joan de Déu; Hospital Nuestra Señora de Gracia; HC Marbella Internacional Hospital; Hospital La Princesa; Hospital Josep Trueta; Hospital Dos de Maig; Hospital Arnau de Vilanova-Lliria; Hospital General Universitario de Elche; Hospital Clínico Universitario de Valencia; Complejo Asistencial de Ávila; Hospital Comarcal de Alcañiz; Hospital Universitario … See abstract for full author list ➔ Berenguer J, et al. Clin Microbiol Infect. 2020 Nov;26(11):1525-1536. doi: 10.1016/j.cmi.2020.07.024. Epub 2020 Aug 4. Clin Microbiol Infect. 2020. PMID: 32758659 Free PMC article.
Seventeen factors were independently associated with an increased hazard of death, the strongest among them including advanced age, liver cirrhosis, low age-adjusted oxygen saturation, higher concentrations of C-reactive protein and lower estimated glomerular filtration ra …
Seventeen factors were independently associated with an increased hazard of death, the strongest among them including advanced age, liver ci …
Expression in Escherichia coli, purification and kinetic characterization of LAPLm, a Leishmania major M17-aminopeptidase.
Aguado ME, González-Matos M, Izquierdo M, Quintana J, Field MC, González-Bacerio J. Aguado ME, et al. Protein Expr Purif. 2021 Jul;183:105877. doi: 10.1016/j.pep.2021.105877. Epub 2021 Mar 25. Protein Expr Purif. 2021. PMID: 33775769
Production of rLAPLm in E. coli Lemo21(DE3), induced for 4 h at 37 C with 400 muM IPTG and 250 muM l-rhamnose, yielded insoluble enzyme with a low proportion of soluble and active protein, only detected by an anti-His antibody-based western-blot. rLAPLm was purified in a s …
Production of rLAPLm in E. coli Lemo21(DE3), induced for 4 h at 37 C with 400 muM IPTG and 250 muM l-rhamnose, yielded insoluble enzy …
Breakthrough candidaemia in the era of broad-spectrum antifungal therapies.
Cuervo G, Garcia-Vidal C, Nucci M, Puchades F, Fernández-Ruiz M, Obed M, Manzur A, Gudiol C, Pemán J, Aguado JM, Ayats J, Carratalà J. Cuervo G, et al. Clin Microbiol Infect. 2016 Feb;22(2):181-188. doi: 10.1016/j.cmi.2015.09.029. Epub 2015 Oct 13. Clin Microbiol Infect. 2016. PMID: 26460064 Free article.
The Candida spp. isolated were different depending on the previous antifungal therapy: previous azole treatment was associated with fluconazole non-susceptible strains and previous echinocandin treatment was associated with BrC caused by C. parapsilosis. These results shou …
The Candida spp. isolated were different depending on the previous antifungal therapy: previous azole treatment was associated with fluconaz …
Prevalence and 30-Day Mortality in Hospitalized Patients With Covid-19 and Prior Lung Diseases.
Signes-Costa J, Núñez-Gil IJ, Soriano JB, Arroyo-Espliguero R, Eid CM, Romero R, Uribarri A, Fernández-Rozas I, Aguado MG, Becerra-Muñoz VM, Huang J, Pepe M, Cerrato E, Raposeiras S, Gonzalez A, Franco-Leon F, Wang L, Alfonso E, Ugo F, García-Prieto JF, Feltes G, Abumayyaleh M, Espejo-Paeres C, Jativa J, Masjuan AL, Macaya C, Carbonell Asíns JA, Estrada V; HOPE COVID-19 investigators. Signes-Costa J, et al. Arch Bronconeumol. 2021 Apr;57:13-20. doi: 10.1016/j.arbres.2020.11.012. Epub 2020 Dec 16. Arch Bronconeumol. 2021. PMID: 34629634 Free PMC article.

Kaplan-Meier curves showed that patients with lung diseases had a worse 30-day survival (HR = 1.78; 95%C.I. 1.58-2.01; p < 0.001) and COPD had almost 40% mortality. Multivariable Cox regression showed that prior lung disease remained a risk factor for mortality (HR, 1.2

Kaplan-Meier curves showed that patients with lung diseases had a worse 30-day survival (HR = 1.78; 95%C.I. 1.58-2.01; p < 0.001)

Aqueous heavy metals removal by adsorption on amine-functionalized mesoporous silica.
Aguado J, Arsuaga JM, Arencibia A, Lindo M, Gascón V. Aguado J, et al. J Hazard Mater. 2009 Apr 15;163(1):213-21. doi: 10.1016/j.jhazmat.2008.06.080. Epub 2008 Jun 28. J Hazard Mater. 2009. PMID: 18675509
Whole copper adsorption isotherms have been obtained at 25 degrees C. Significant maximum adsorption capacities have been found with excellent behavior at low concentration....
Whole copper adsorption isotherms have been obtained at 25 degrees C. Significant maximum adsorption capacities have been found with …
Risk factors for bacteremia in urinary tract infections attended in the emergency department.
Lalueza A, Sanz-Trepiana L, Bermejo N, Yaiza B, Morales-Cartagena A, Espinosa M, García-Jiménez R, Jiménez-Rodríguez O, Ponce B, Lora D, Orellana MÁ, Fernández-Ruiz M, Bermejo S, Aguado JM. Lalueza A, et al. Intern Emerg Med. 2018 Jan;13(1):41-50. doi: 10.1007/s11739-016-1576-6. Epub 2016 Nov 18. Intern Emerg Med. 2018. PMID: 27864665
In a multivariate analysis, variables associated with b-UTI were: solid organ malignancy (OR 3.19; CI 95% 1.01-10.03, p = 0.04), elevated neutrophil count (more than 80% of neutrophils) (OR 5.84; CI 95% 2.13-15.99, p = 0.0006), elevated C reactive protein (OR 1.046; CI 95% …
In a multivariate analysis, variables associated with b-UTI were: solid organ malignancy (OR 3.19; CI 95% 1.01-10.03, p = 0.04), elevated ne …
mPGES-1 (Microsomal Prostaglandin E Synthase-1) Mediates Vascular Dysfunction in Hypertension Through Oxidative Stress.
Avendaño MS, García-Redondo AB, Zalba G, González-Amor M, Aguado A, Martínez-Revelles S, Beltrán LM, Camacho M, Cachofeiro V, Alonso MJ, Salaices M, Briones AM. Avendaño MS, et al. Hypertension. 2018 Aug;72(2):492-502. doi: 10.1161/HYPERTENSIONAHA.118.10833. Epub 2018 Jun 11. Hypertension. 2018. PMID: 29891646 Free article.
In vascular smooth muscle cells or aortic segments, PGE(2) increased NADPH oxidase expression and activity and reduced mitochondrial membrane potential, effects that were abolished by antagonists of the PGE(2) receptors (EP), EP1 and EP3, and by JNK (c-Jun N-terminal kinas …
In vascular smooth muscle cells or aortic segments, PGE(2) increased NADPH oxidase expression and activity and reduced mitochondrial membran …
24 results