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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 5
2003 5
2004 5
2005 21
2006 18
2007 19
2008 21
2009 21
2010 31
2011 31
2012 33
2013 48
2014 48
2015 64
2016 65
2017 59
2018 69
2019 82
2020 39
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Search Results

619 results
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Page 1
Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor.
Janes MR, Zhang J, Li LS, Hansen R, Peters U, Guo X, Chen Y, Babbar A, Firdaus SJ, Darjania L, Feng J, Chen JH, Li S, Li S, Long YO, Thach C, Liu Y, Zarieh A, Ely T, Kucharski JM, Kessler LV, Wu T, Yu K, Wang Y, Yao Y, Deng X, Zarrinkar PP, Brehmer D, Dhanak D, Lorenzi MV, Hu-Lowe D, Patricelli MP, Ren P, Liu Y. Janes MR, et al. Among authors: Feng J. Cell. 2018 Jan 25;172(3):578-589.e17. doi: 10.1016/j.cell.2018.01.006. Cell. 2018. PMID: 29373830 Free article.
The reactivity-driven biochemical mechanism of covalent KRASG12C inhibitors.
Hansen R, Peters U, Babbar A, Chen Y, Feng J, Janes MR, Li LS, Ren P, Liu Y, Zarrinkar PP. Hansen R, et al. Among authors: Feng J. Nat Struct Mol Biol. 2018 Jun;25(6):454-462. doi: 10.1038/s41594-018-0061-5. Epub 2018 May 14. Nat Struct Mol Biol. 2018. PMID: 29760531
Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State.
Patricelli MP, Janes MR, Li LS, Hansen R, Peters U, Kessler LV, Chen Y, Kucharski JM, Feng J, Ely T, Chen JH, Firdaus SJ, Babbar A, Ren P, Liu Y. Patricelli MP, et al. Among authors: Feng J. Cancer Discov. 2016 Mar;6(3):316-29. doi: 10.1158/2159-8290.CD-15-1105. Epub 2016 Jan 6. Cancer Discov. 2016. PMID: 26739882 Free article.
Comparison of Nicotine and Toxicant Exposure in Users of Electronic Cigarettes and Combustible Cigarettes.
Goniewicz ML, Smith DM, Edwards KC, Blount BC, Caldwell KL, Feng J, Wang L, Christensen C, Ambrose B, Borek N, van Bemmel D, Konkel K, Erives G, Stanton CA, Lambert E, Kimmel HL, Hatsukami D, Hecht SS, Niaura RS, Travers M, Lawrence C, Hyland AJ. Goniewicz ML, et al. Among authors: Feng J. JAMA Netw Open. 2018 Dec 7;1(8):e185937. doi: 10.1001/jamanetworkopen.2018.5937. JAMA Netw Open. 2018. PMID: 30646298 Free PMC article.
Targeting S-adenosylmethionine biosynthesis with a novel allosteric inhibitor of Mat2A.
Quinlan CL, Kaiser SE, BolaƱos B, Nowlin D, Grantner R, Karlicek-Bryant S, Feng JL, Jenkinson S, Freeman-Cook K, Dann SG, Wang X, Wells PA, Fantin VR, Stewart AE, Grant SK. Quinlan CL, et al. Among authors: Feng JL. Nat Chem Biol. 2017 Jul;13(7):785-792. doi: 10.1038/nchembio.2384. Epub 2017 May 29. Nat Chem Biol. 2017. PMID: 28553945
WITHDRAWN: Discovery of SHR1977: A highly potent and selective ROMK inhibitor.
Li X, Zhang Y, Chen Y, He W, Wan H, Zhang L, Hu Q, Feng J, Yuan J, Dong Q, Cao G, Zhang L, He F, Bai C, Tao W. Li X, et al. Among authors: Feng J. Bioorg Med Chem Lett. 2016 Jun 27:S0960-894X(16)30683-7. doi: 10.1016/j.bmcl.2016.06.072. Online ahead of print. Bioorg Med Chem Lett. 2016. PMID: 27377326
Discovery and development of pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer.
Li X, Yang C, Wan H, Zhang G, Feng J, Zhang L, Chen X, Zhong D, Lou L, Tao W, Zhang L. Li X, et al. Among authors: Feng J. Eur J Pharm Sci. 2017 Dec 15;110:51-61. doi: 10.1016/j.ejps.2017.01.021. Epub 2017 Jan 21. Eur J Pharm Sci. 2017. PMID: 28115222
619 results
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