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2007 1
2017 2
2020 0
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Locally-applied 5-fluorouracil-loaded slow-release patch prevents pancreatic cancer growth in an orthotopic mouse model.
Shim IK, Yi HJ, Yi HG, Lee CM, Lee YN, Choi YJ, Jeong SY, Jun E, Hoffman RM, Cho DW, Kim SC. Shim IK, et al. Oncotarget. 2017 Jun 20;8(25):40140-40151. doi: 10.18632/oncotarget.17370. Oncotarget. 2017. PMID: 28498800 Free PMC article.
The drug patch delivered a 30.2 times higher level of 5-FU than an intra-peritoneal (i.p.) bolus injection on day-1. High 5-FU levels were accumulated within one week by the patch. Four groups were compared for efficacy of 5-FU. Drug-free patch as a negative …
The drug patch delivered a 30.2 times higher level of 5-FU than an intra-peritoneal (i.p.) bolus injection on day-1. High 5-FU
Synergistic effect of a drug loaded electrospun patch and systemic chemotherapy in pancreatic cancer xenograft.
Jun E, Kim SC, Lee CM, Oh J, Lee S, Shim IK. Jun E, et al. Sci Rep. 2017 Sep 28;7(1):12381. doi: 10.1038/s41598-017-12670-3. Sci Rep. 2017. PMID: 28959053 Free PMC article.
Poly-L-lactic acid-based 5-FU releasing patch was fabricated by electrospinning, and its tumour killing effects were first confirmed in vitro. ...Systemic gemcitabine treatment group, 5-FU drug releasing patch group, and systemic gemcitabine plus 5-FU patch g …
Poly-L-lactic acid-based 5-FU releasing patch was fabricated by electrospinning, and its tumour killing effects were first confirmed …
Change of the expression of human telomerase reverse transcriptase mRNA and human telomerase RNA after cisplatin and 5-fluorouracil exposure in head and neck squamous cell carcinoma cell lines.
Lee BJ, Lee BH, Wang SG, Lee JC, Roh HJ, Goh EK, Kim CM, Jun ES. Lee BJ, et al. J Korean Med Sci. 2007 Sep;22 Suppl(Suppl):S73-8. doi: 10.3346/jkms.2007.22.S.S73. J Korean Med Sci. 2007. PMID: 17923759 Free PMC article.
Cell cytotoxicity, the change of telomerase activity, and hTERT mRNA and hTR expression by 5-FU and cisplatin exposure were assessed by MTT assay, TRAP assay, and real-time RT-PCR, respectively. ...However, in both cell lines, the telomerase activity and hTR did not show a …
Cell cytotoxicity, the change of telomerase activity, and hTERT mRNA and hTR expression by 5-FU and cisplatin exposure were assessed …
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