Circulating Tumor DNA Profiling From Breast Cancer Screening Through to Metastatic Disease.
Page K, Martinson LJ, Fernandez-Garcia D, Hills A, Gleason KLT, Gray MC, Rushton AJ, Nteliopoulos G, Hastings RK, Goddard K, Ions C, Parmar V, Primrose L, Openshaw MR, Guttery DS, Palmieri C, Ali S, Stebbing J, Coombes RC, Shaw JA.
Page K, et al.
JCO Precis Oncol. 2021 Nov 24;5:PO.20.00522. doi: 10.1200/PO.20.00522. eCollection 2021.
JCO Precis Oncol. 2021.
PMID: 34849446
Free PMC article.
Only 15 individuals had evidence of potential clonal hematopoiesis of indeterminate potential mutations. CONCLUSION: We were able detect ctDNA across the breast cancer spectrum, notably in MBC where variants in ESR1, TP53, and PIK3CA predicted poor overall survival. ...
Only 15 individuals had evidence of potential clonal hematopoiesis of indeterminate potential mutations. CONCLUSION: We were able det …