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The following term was not found in PubMed: Kai-An
Page 1
Lysis from without.
Abedon ST. Abedon ST. Bacteriophage. 2011 Jan;1(1):46-49. doi: 10.4161/bact.1.1.13980. Bacteriophage. 2011. PMID: 21687534 Free PMC article.
The action on bacteria of exogenously supplied phage lysin, too, has been described as a form of LO (here, LO(L)). LO(V) has been somewhat worked out mechanistically for T4 phages, has been used to elucidate various phage-associated phenomena including discov …
The action on bacteria of exogenously supplied phage lysin, too, has been described as a form of LO (here, LO(L)). LO(V …
An epigenetically distinct HSC subset supports thymic reconstitution.
Elias HK, Mitra S, da Silva MB, Rajagopalan A, Gipson B, Lee N, Kousa AI, Ali MAE, Grassman S, Zhang X, DeWolf S, Smith M, Andrlova H, Argyropoulos KV, Sharma R, Fei T, Sun JC, Dunbar CE, Park CY, Leslie CS, Bhandoola A, van den Brink MRM. Elias HK, et al. bioRxiv [Preprint]. 2024 Jun 21:2024.06.06.597775. doi: 10.1101/2024.06.06.597775. bioRxiv. 2024. PMID: 38895335 Free PMC article. Preprint.
We therefore studied the thymic reconstituting and T-cell potential of Kit (lo) HSCs. Using a preclinical allo-HCT model, we demonstrate that Kit (lo) HSCs support better thymic recovery, and T-cell reconstitution resulting in improved T cell responses to infection …
We therefore studied the thymic reconstituting and T-cell potential of Kit (lo) HSCs. Using a preclinical allo-HCT model, we demonstr …
Extracellular Vesicles heterogeneity through the lens of multiomics.
Silva TF, Hutchins E, Zhao W, Ciani Y, Kim M, Mariscal J, Qiu Z, Kittel A, Zhou B, Wang Y, Hall M, Galasso F, Reiman R, Freeman MR, Parker S, Van Eyk J, Yang W, Posadas E, Guarnerio J, Nolan J, Thery C, Zijlstra A, Stott S, You S, Demichelis F, Boutros P, Van Keuren-Jensen K, Di Vizio D. Silva TF, et al. bioRxiv [Preprint]. 2024 Aug 19:2024.08.14.607999. doi: 10.1101/2024.08.14.607999. bioRxiv. 2024. Update in: Cell Rep Med. 2025 Jun 6:102161. doi: 10.1016/j.xcrm.2025.102161. PMID: 39229160 Free PMC article. Updated. Preprint.
Beside small EVs, aggressive tumor cells release a population of particularly large EVs, namely large oncosomes (LO). This study provides the first resource of label-free quantitative proteomics of LO and small EVs obtained from distinct cancer cell types (prostate, …
Beside small EVs, aggressive tumor cells release a population of particularly large EVs, namely large oncosomes (LO). This study prov …
Veterinary Students' Use of Learning Objectives.
Olin SJ, Springer C, Royal K. Olin SJ, et al. J Vet Med Educ. 2022 Dec;49(6):751-758. doi: 10.3138/jvme-2021-0023. Epub 2021 Aug 3. J Vet Med Educ. 2022. PMID: 34342544
Learning objectives (LO) are the foundation of a competency-based curriculum, but no studies assess how students use LO for exam preparation and/or their general attitudes toward LO. ...In conclusion, students did not prefer more detailed LO and LO
Learning objectives (LO) are the foundation of a competency-based curriculum, but no studies assess how students use LO for ex …
Lateralized and Segmental Overgrowth in Children.
Mussa A, Carli D, Cardaropoli S, Ferrero GB, Resta N. Mussa A, et al. Cancers (Basel). 2021 Dec 7;13(24):6166. doi: 10.3390/cancers13246166. Cancers (Basel). 2021. PMID: 34944785 Free PMC article. Review.
Recently, next-generation sequencing approaches have increased the knowledge on the molecular defects in LO, allowing classifying them based on the deranged cellular signaling pathway. LO is caused by either genetic or epigenetic somatic anomalies affecting cell pro …
Recently, next-generation sequencing approaches have increased the knowledge on the molecular defects in LO, allowing classifying the …
LPS Increases 5-LO Expression on Monocytes via an Activation of Akt-Sp1/NF-kappaB Pathways.
Lee SJ, Seo KW, Kim CD. Lee SJ, et al. Korean J Physiol Pharmacol. 2015 May;19(3):263-8. doi: 10.4196/kjpp.2015.19.3.263. Epub 2015 Apr 30. Korean J Physiol Pharmacol. 2015. PMID: 25954132 Free PMC article.
5-Lipoxygenase (5-LO) plays a pivotal role in the progression of atherosclerosis. Therefore, this study investigated the molecular mechanisms involved in 5-LO expression on monocytes induced by LPS. Stimulation of THP-1 monocytes with LPS (0~3 g/ml) increased 5-L
5-Lipoxygenase (5-LO) plays a pivotal role in the progression of atherosclerosis. Therefore, this study investigated the molecular me …
Occurrences and Functions of Ly6C(hi) and Ly6C(lo) Macrophages in Health and Disease.
Li YH, Zhang Y, Pan G, Xiang LX, Luo DC, Shao JZ. Li YH, et al. Front Immunol. 2022 May 30;13:901672. doi: 10.3389/fimmu.2022.901672. eCollection 2022. Front Immunol. 2022. PMID: 35707538 Free PMC article. Review.
In this review, we discuss the basic biology of Ly6C(hi) and Ly6C(lo) macrophages, including their origin, differentiation, and phenotypic switching, and the diverse functions of Ly6C(hi) and Ly6C(lo) macrophages in homeostasis and disease, including in injury, chro …
In this review, we discuss the basic biology of Ly6C(hi) and Ly6C(lo) macrophages, including their origin, differentiation, and pheno …
Lipoxygenase pathways in atherogenesis.
Zhao L, Funk CD. Zhao L, et al. Trends Cardiovasc Med. 2004 Jul;14(5):191-5. doi: 10.1016/j.tcm.2004.04.003. Trends Cardiovasc Med. 2004. PMID: 15261891 Review.
15-lipoxygenase-1 (also known as 12/15-LO in mice) and 5-LO/5-LO-activating protein (FLAP) cascades play central roles in low-density lipoprotein oxidation and leukotriene biosynthesis, respectively. Several genetic and expression studies unraveling an associ …
15-lipoxygenase-1 (also known as 12/15-LO in mice) and 5-LO/5-LO-activating protein (FLAP) cascades play central roles …
Modulation of microRNA processing by 5-lipoxygenase.
Uebbing S, Kreiß M, Scholl F, Häfner AK, Sürün D, Garscha U, Werz O, Basavarajappa D, Samuelsson B, Rådmark O, Suess B, Steinhilber D. Uebbing S, et al. FASEB J. 2021 Feb;35(2):e21193. doi: 10.1096/fj.202002108R. Epub 2020 Nov 17. FASEB J. 2021. PMID: 33205517
Here, we describe modulation of miRNA processing as a novel noncanonical function of the 5-lipoxygenase (5-LO) enzyme in monocytic cells. In differentiated Mono Mac 6 (MM6) cells, we found an in situ interaction of 5-LO with Dicer, a key enzyme in miRNA biogenesis. …
Here, we describe modulation of miRNA processing as a novel noncanonical function of the 5-lipoxygenase (5-LO) enzyme in monocytic ce …
Making a tool of an artifact: the application of photoinduced Lo domains in giant unilamellar vesicles to the study of Lo/Ld phase spinodal decomposition and its modulation by the ganglioside GM1.
Staneva G, Seigneuret M, Conjeaud H, Puff N, Angelova MI. Staneva G, et al. Langmuir. 2011 Dec 20;27(24):15074-82. doi: 10.1021/la203101y. Epub 2011 Nov 14. Langmuir. 2011. PMID: 22026409
Lo domains are usually imaged using fluorescence microscopy of differentially phase-partionioning membrane-embedded probes. ...GM1 also has the effect of destabilizing Lo microdomains. These properties may have consequences for Lo nanodomains stability and th
Lo domains are usually imaged using fluorescence microscopy of differentially phase-partionioning membrane-embedded probes. ...GM1 al
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