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Year Number of Results
2002 3
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2009 5
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2011 8
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71 results

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Enhanced broad spectrum in vitro antiviral efficacy of 3-F-4-MeO-Bn, 3-CN, and 4-CN derivatives of lipid remdesivir nucleoside monophosphate prodrugs.
McMillan RE, Lo MK, Zhang XQ, Beadle JR, Valiaeva N, Garretson AF, Clark AE, Freshman JE, Murphy J, Montgomery JM, Spiropoulou CF, Schooley RT, Hostetler KY, Carlin AF. McMillan RE, et al. Among authors: hostetler ky. Antiviral Res. 2023 Nov;219:105718. doi: 10.1016/j.antiviral.2023.105718. Epub 2023 Sep 25. Antiviral Res. 2023. PMID: 37758067 Free PMC article.
Rethinking Remdesivir: Synthesis, Antiviral Activity, and Pharmacokinetics of Oral Lipid Prodrugs.
Schooley RT, Carlin AF, Beadle JR, Valiaeva N, Zhang XQ, Clark AE, McMillan RE, Leibel SL, McVicar RN, Xie J, Garretson AF, Smith VI, Murphy J, Hostetler KY. Schooley RT, et al. Among authors: hostetler ky. Antimicrob Agents Chemother. 2021 Sep 17;65(10):e0115521. doi: 10.1128/AAC.01155-21. Epub 2021 Jul 26. Antimicrob Agents Chemother. 2021. PMID: 34310217 Free PMC article.
1-O-Octadecyl-2-O-benzyl-sn-glyceryl-3-phospho-GS-441524 (V2043). Evaluation of Oral V2043 in a Mouse Model of SARS-CoV-2 Infection and Synthesis and Antiviral Evaluation of Additional Phospholipid Esters with Enhanced Anti-SARS-CoV-2 Activity.
Carlin AF, Beadle JR, Clark AE, Gully KL, Moreira FR, Baric RS, Graham RL, Valiaeva N, Leibel SL, Bray W, McMillan RE, Freshman JE, Garretson AF, McVicar RN, Rana T, Zhang XQ, Murphy JA, Schooley RT, Hostetler KY. Carlin AF, et al. Among authors: hostetler ky. J Med Chem. 2023 Apr 27;66(8):5802-5819. doi: 10.1021/acs.jmedchem.3c00046. Epub 2023 Apr 11. J Med Chem. 2023. PMID: 37040439 Free PMC article.
Rethinking Remdesivir: Synthesis, Antiviral Activity and Pharmacokinetics of Oral Lipid Prodrugs.
Schooley RT, Carlin AF, Beadle JR, Valiaeva N, Zhang XQ, Clark AE, McMillan RE, Leibel SL, McVicar RN, Xie J, Garretson AF, Smith VI, Murphy J, Hostetler KY. Schooley RT, et al. Among authors: hostetler ky. bioRxiv [Preprint]. 2021 Jun 7:2020.08.26.269159. doi: 10.1101/2020.08.26.269159. bioRxiv. 2021. Update in: Antimicrob Agents Chemother. 2021 Sep 17;65(10):e0115521. doi: 10.1128/AAC.01155-21. PMID: 32869033 Free PMC article. Updated. Preprint.
Broad-Spectrum In Vitro Antiviral Activity of ODBG-P-RVn: An Orally-Available, Lipid-Modified Monophosphate Prodrug of Remdesivir Parent Nucleoside (GS-441524).
Lo MK, Shrivastava-Ranjan P, Chatterjee P, Flint M, Beadle JR, Valiaeva N, Murphy J, Schooley RT, Hostetler KY, Montgomery JM, Spiropoulou CF. Lo MK, et al. Among authors: hostetler ky. Microbiol Spectr. 2021 Dec 22;9(3):e0153721. doi: 10.1128/Spectrum.01537-21. Epub 2021 Nov 24. Microbiol Spectr. 2021. PMID: 34817209 Free PMC article.
Broad-spectrum in vitro antiviral activity of ODBG-P-RVn: an orally-available, lipid-modified monophosphate prodrug of remdesivir parent nucleoside (GS-441524).
Lo MK, Shrivastava-Ranjan P, Chatterjee P, Flint M, Beadle JR, Valiaeva N, Schooley RT, Hostetler KY, Montgomery JM, Spiropoulou C. Lo MK, et al. Among authors: hostetler ky. bioRxiv [Preprint]. 2021 Aug 10:2021.08.06.455494. doi: 10.1101/2021.08.06.455494. bioRxiv. 2021. Update in: Microbiol Spectr. 2021 Dec 22;9(3):e0153721. doi: 10.1128/Spectrum.01537-21. PMID: 34401879 Free PMC article. Updated. Preprint.
Oral pharmacokinetics and efficacy of oral phospholipid remdesivir nucleoside prodrugs against SARS-CoV-2 in mice.
Carlin AF, Beadle JR, Ardanuy J, Clark AE, Rhodes V, Garretson AF, Murphy JA, Valiaeva N, Schooley RT, Frieman MB, Hostetler KY. Carlin AF, et al. Among authors: hostetler ky. Antimicrob Agents Chemother. 2024 Oct 8;68(10):e0103924. doi: 10.1128/aac.01039-24. Epub 2024 Sep 6. Antimicrob Agents Chemother. 2024. PMID: 39240093 Free PMC article.
Anti-BK virus activity of nucleoside analogs.
Randhawa P, Zemlicka J, Sauerbrei A, Meier C, Hostetler KY, Beadle JR, Farasati NA, Huang Y, Bradley M. Randhawa P, et al. Among authors: hostetler ky. Antimicrob Agents Chemother. 2008 Apr;52(4):1519-21. doi: 10.1128/AAC.01241-07. Epub 2008 Feb 19. Antimicrob Agents Chemother. 2008. PMID: 18285481 Free PMC article.
71 results