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Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy.
Kiryluk K, Sanchez-Rodriguez E, Zhou XJ, Zanoni F, Liu L, Mladkova N, Khan A, Marasa M, Zhang JY, Balderes O, Sanna-Cherchi S, Bomback AS, Canetta PA, Appel GB, Radhakrishnan J, Trimarchi H, Sprangers B, Cattran DC, Reich H, Pei Y, Ravani P, Galesic K, Maixnerova D, Tesar V, Stengel B, Metzger M, Canaud G, Maillard N, Berthoux F, Berthelot L, Pillebout E, Monteiro R, Nelson R, Wyatt RJ, Smoyer W, Mahan J, Samhar AA, Hidalgo G, Quiroga A, Weng P, Sreedharan R, Selewski D, Davis K, Kallash M, Vasylyeva TL, Rheault M, Chishti A, Ranch D, Wenderfer SE, Samsonov D, Claes DJ, Akchurin O, Goumenos D, Stangou M, Nagy J, Kovacs T, Fiaccadori E, Amoroso A, Barlassina C, Cusi D, Del Vecchio L, Battaglia GG, Bodria M, Boer E, Bono L, Boscutti G, Caridi G, Lugani F, Ghiggeri G, Coppo R, Peruzzi L, Esposito V, Esposito C, Feriozzi S, Polci R, Frasca G, Galliani M, Garozzo M, Mitrotti A, Gesualdo L, Granata S, Zaza G, Londrino F, Magistroni R, Pisani I, Magnano A, Marcantoni C, Messa P, Mignani R, Pani A, Ponticelli C, Roccatello D, Salvadori M, Salvi E, Santoro D, Gembillo G, Savoldi S, Spotti D, Zamboli P, Izzi C, Alberici F, Delbarba E, Florczak M, Krata N, Mucha K, Pączek L, Niemczyk S, Mosz… See abstract for full author list ➔ Kiryluk K, et al. Nat Genet. 2023 Jul;55(7):1091-1105. doi: 10.1038/s41588-023-01422-x. Epub 2023 Jun 19. Nat Genet. 2023. PMID: 37337107
Rejecting political correctness.
Cohen D, Fister K. Cohen D, et al. BMJ. 2005 Jan 8;330(7482):62. doi: 10.1136/bmj.330.7482.62. BMJ. 2005. PMID: 15637368 Free PMC article.
Karol Sikora, dean elect of Britain's first private medical school, thinks the school will widen access to education. ...
Karol Sikora, dean elect of Britain's first private medical school, thinks the school will widen access to education. .
Personalized cancer therapy.
Sikora K. Sikora K. Per Med. 2005 Mar;2(1):5-9. doi: 10.1517/17410541.2.1.5. Per Med. 2005. PMID: 29793233
Karol Sikora is the Scientific Director of Medical Solutions Plc and Special Advisor to HCA International in the creation of the London Cancer Group - the largest UK cancer network outside the NHS in HCA's six major London private hospitals. ...
Karol Sikora is the Scientific Director of Medical Solutions Plc and Special Advisor to HCA International in the creation of t
The Study of Antistaphylococcal Potential of Omiganan and Retro-Omiganan Under Flow Conditions.
Jaśkiewicz M, Neubauer D, Sikora K, Bauer M, Bartoszewska S, Błażewicz I, Marek D, Barańska-Rybak W, Kamysz W. Jaśkiewicz M, et al. Probiotics Antimicrob Proteins. 2024 Jan 15. doi: 10.1007/s12602-023-10197-w. Online ahead of print. Probiotics Antimicrob Proteins. 2024. PMID: 38224448
The aim of this study was to investigate the activity of both compounds against S. aureus biofilm under flow conditions. The advantage of this approach was that it offered the opportunity to form and characterize the biofilm under more controlled conditions. ...
The aim of this study was to investigate the activity of both compounds against S. aureus biofilm under flow conditions. The advantag …
Quaternary Ammonium Salts of Cationic Lipopeptides with Lysine Residues - Synthesis, Antimicrobial, Hemolytic and Cytotoxic Activities.
Sikora K, Jędrzejczak J, Bauer M, Neubauer D, Jaśkiewicz M, Szaryńska M. Sikora K, et al. Probiotics Antimicrob Proteins. 2023 Dec;15(6):1465-1483. doi: 10.1007/s12602-023-10161-8. Epub 2023 Sep 29. Probiotics Antimicrob Proteins. 2023. PMID: 37770629 Free PMC article.
Furthermore, the toxicity against red blood cells and human keratinocytes was assessed. It's worth emphasizing that qUSCLs were less toxic than the parent molecules of comparative hydrophobicity. ...
Furthermore, the toxicity against red blood cells and human keratinocytes was assessed. It's worth emphasizing that qUSCLs were less …
Correlation between DNA content, expression of Ki-67 antigen of tumor cells and immunophenotype of lymphocytes from malignant pleural effusions.
Sikora J, Dworacki G, Trybus M, Batura-Gabryel H, Zeromski J. Sikora J, et al. Tumour Biol. 1998;19(3):196-204. doi: 10.1159/000030007. Tumour Biol. 1998. PMID: 9591046
Malignant cells isolated from 26 malignant pleural effusions, collected from patients bearing metastatic carcinoma, were examined using flow cytometry. Expression of Ki-67 antigen, DNA ploidy, S phase fraction, DNA index of tumor cells and the percentage of aneuploid cell …
Malignant cells isolated from 26 malignant pleural effusions, collected from patients bearing metastatic carcinoma, were examined using flow …
DNA ploidy, S-phase, and Ki-67 antigen expression in the evaluation of cell content of pleural effusions.
Sikora J, Dworacki G, Zeromski J. Sikora J, et al. Lung. 1996;174(5):303-13. doi: 10.1007/BF00176189. Lung. 1996. PMID: 8843056
The latter included the evaluation of DNA ploidy, the calculation of DNA index (DI), the determination of S phase fraction (SPF), and cell proliferation associated with Ki-67 antigen expression. ...
The latter included the evaluation of DNA ploidy, the calculation of DNA index (DI), the determination of S phase fraction (SPF), and …