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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 6
2003 3
2005 2
2006 2
2009 2
2010 1
2012 3
2013 5
2014 2
2015 1
2016 5
2017 3
2018 1
2019 2
2020 0
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36 results
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Page 1
Tonantzitlolone is a nanomolar potency activator of transient receptor potential canonical 1/4/5 channels.
Rubaiy HN, Ludlow MJ, Siems K, Norman K, Foster R, Wolf D, Beutler JA, Beech DJ. Rubaiy HN, et al. Among authors: siems k. Br J Pharmacol. 2018 Aug;175(16):3361-3368. doi: 10.1111/bph.14379. Epub 2018 Jun 28. Br J Pharmacol. 2018. PMID: 29859013 Free PMC article.
Synthesis and antiproliferative activity of new tonantzitlolone-derived diterpene derivatives.
Busch T, Dräger G, Kunst E, Benson H, Sasse F, Siems K, Kirschning A. Busch T, et al. Among authors: siems k. Org Biomol Chem. 2016 Oct 14;14(38):9040-5. doi: 10.1039/c6ob01697a. Epub 2016 Sep 7. Org Biomol Chem. 2016. PMID: 27604289
Phytochemicals Rosmarinic Acid, Ampelopsin, and Amorfrutin-A Can Modulate Age-Related Phenotype of Serially Passaged Human Skin Fibroblasts in vitro.
Sodagam L, Lewinska A, Kwasniewicz E, Kokhanovska S, Wnuk M, Siems K, Rattan SIS. Sodagam L, et al. Among authors: siems k. Front Genet. 2019 Feb 21;10:81. doi: 10.3389/fgene.2019.00081. eCollection 2019. Front Genet. 2019. PMID: 30847003 Free PMC article.
Plant-Derived Molecules α-Boswellic Acid Acetate, Praeruptorin-A, and Salvianolic Acid-B Have Age-Related Differential Effects in Young and Senescent Human Fibroblasts In Vitro.
Lewinska A, Sodagam L, Bloniarz D, Siems K, Wnuk M, Rattan SIS. Lewinska A, et al. Among authors: siems k. Molecules. 2019 Dec 29;25(1):141. doi: 10.3390/molecules25010141. Molecules. 2019. PMID: 31905790 Free PMC article.
Ageing with elegans: a research proposal to map healthspan pathways.
Luyten W, Antal P, Braeckman BP, Bundy J, Cirulli F, Fang-Yen C, Fuellen G, Leroi A, Liu Q, Martorell P, Metspalu A, Perola M, Ristow M, Saul N, Schoofs L, Siems K, Temmerman L, Smets T, Wolk A, Rattan SI. Luyten W, et al. Among authors: siems k. Biogerontology. 2016 Aug;17(4):771-82. doi: 10.1007/s10522-016-9644-x. Epub 2016 Apr 4. Biogerontology. 2016. PMID: 27040825
Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent.
Sourbier C, Scroggins BT, Mannes PZ, Liao PJ, Siems K, Wolf D, Beutler JA, Linehan WM, Neckers L. Sourbier C, et al. Among authors: siems k. Oncotarget. 2015 Oct 6;6(30):29963-74. doi: 10.18632/oncotarget.4676. Oncotarget. 2015. PMID: 26298773 Free PMC article.
Flavonol Glycosides and Cytotoxic Steroidal Saponins from Furcraea tuberosa (Agavaceae).
Tapondjou LA, Jenett-Siems K, Siems K, Weng A, Melzig MF. Tapondjou LA, et al. Among authors: siems k. Nat Prod Commun. 2017 Mar;12(3):347-350. Nat Prod Commun. 2017. PMID: 30549882
Rational approaches to natural-product-based drug design.
Haustedt LO, Mang C, Siems K, Schiewe H. Haustedt LO, et al. Among authors: siems k. Curr Opin Drug Discov Devel. 2006 Jul;9(4):445-62. Curr Opin Drug Discov Devel. 2006. PMID: 16889228 Review.
Triterpene glycosides from the leaves of Pittosporum angustifolium.
Bäcker C, Jenett-Siems K, Siems K, Wurster M, Bodtke A, Chamseddin C, Crüsemann M, Lindequist U. Bäcker C, et al. Among authors: siems k. Planta Med. 2013 Oct;79(15):1461-9. doi: 10.1055/s-0033-1350806. Epub 2013 Sep 17. Planta Med. 2013. PMID: 24046217
Characterisation of Nox4 inhibitors from edible plants.
Kofler PA, Pircher H, von Grafenstein S, Diener T, Höll M, Liedl KR, Siems K, Jansen-Dürr P. Kofler PA, et al. Among authors: siems k. Planta Med. 2013 Mar;79(3-4):244-52. doi: 10.1055/s-0032-1328129. Epub 2013 Jan 23. Planta Med. 2013. PMID: 23345167
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