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Page 1
Preclinical Development of CAR T Cells with Antigen-Inducible IL18 Enforcement to Treat GD2-Positive Solid Cancers.
Fischer-Riepe L, Kailayangiri S, Zimmermann K, Pfeifer R, Aigner M, Altvater B, Kretschmann S, Völkl S, Hartley J, Dreger C, Petry K, Bosio A, von Döllen A, Hartmann W, Lode H, Görlich D, Mackensen A, Jungblut M, Schambach A, Abken H, Rossig C. Fischer-Riepe L, et al. Among authors: zimmermann k. Clin Cancer Res. 2024 Aug 15;30(16):3564-3577. doi: 10.1158/1078-0432.CCR-23-3157. Clin Cancer Res. 2024. PMID: 38593230
The TRPC5 receptor as pharmacological target for pain and metabolic disease.
Khare P, Chand J, Ptakova A, Liguori R, Ferrazzi F, Bishnoi M, Vlachova V, Zimmermann K. Khare P, et al. Among authors: zimmermann k. Pharmacol Ther. 2024 Nov;263:108727. doi: 10.1016/j.pharmthera.2024.108727. Epub 2024 Oct 9. Pharmacol Ther. 2024. PMID: 39384022 Free article. Review.
KCNQ1 is an essential mediator of the sex-dependent perception of moderate cold temperatures.
Kiper AK, Wegner S, Kadala A, Rinné S, Schütte S, Winter Z, Bertoune MAR, Touska F, Matschke V, Wrobel E, Streit AK, Lang F, Schmidt C, Schulze-Bahr E, Schäfer MK, Voelkl J, Seebohm G, Zimmermann K, Decher N. Kiper AK, et al. Among authors: zimmermann k. Proc Natl Acad Sci U S A. 2024 Jun 18;121(25):e2322475121. doi: 10.1073/pnas.2322475121. Epub 2024 Jun 10. Proc Natl Acad Sci U S A. 2024. PMID: 38857404 Free PMC article.
A TRP channel trio mediates acute noxious heat sensing.
Vandewauw I, De Clercq K, Mulier M, Held K, Pinto S, Van Ranst N, Segal A, Voet T, Vennekens R, Zimmermann K, Vriens J, Voets T. Vandewauw I, et al. Among authors: zimmermann k. Nature. 2018 Mar 29;555(7698):662-666. doi: 10.1038/nature26137. Epub 2018 Mar 14. Nature. 2018. PMID: 29539642
GMP-Compliant Manufacturing of TRUCKs: CAR T Cells targeting GD2 and Releasing Inducible IL-18.
Glienke W, Dragon AC, Zimmermann K, Martyniszyn-Eiben A, Mertens M, Abken H, Rossig C, Altvater B, Aleksandrova K, Arseniev L, Kloth C, Stamopoulou A, Moritz T, Lode HN, Siebert N, Blasczyk R, Goudeva L, Schambach A, Köhl U, Eiz-Vesper B, Esser R. Glienke W, et al. Among authors: zimmermann k. Front Immunol. 2022 Mar 24;13:839783. doi: 10.3389/fimmu.2022.839783. eCollection 2022. Front Immunol. 2022. PMID: 35401506 Free PMC article.
Therapeutic opportunities for targeting cold pain pathways.
Yin K, Zimmermann K, Vetter I, Lewis RJ. Yin K, et al. Among authors: zimmermann k. Biochem Pharmacol. 2015 Jan 15;93(2):125-40. doi: 10.1016/j.bcp.2014.09.024. Epub 2014 Oct 12. Biochem Pharmacol. 2015. PMID: 25316567 Free article. Review.
CAR-Ts redirected against the Thomsen-Friedenreich antigen CD176 mediate specific elimination of malignant cells from leukemia and solid tumors.
Dragon AC, Beermann LM, Umland M, Bonifacius A, Malinconico C, Ruhl L, Kehler P, Gellert J, Weiß L, Mayer-Hain S, Zimmermann K, Riese S, Thol F, Beutel G, Maecker-Kolhoff B, Yamamoto F, Blasczyk R, Schambach A, Hust M, Hudecek M, Eiz-Vesper B. Dragon AC, et al. Among authors: zimmermann k. Front Immunol. 2023 Oct 17;14:1219165. doi: 10.3389/fimmu.2023.1219165. eCollection 2023. Front Immunol. 2023. PMID: 37915564 Free PMC article.
TRPM8-dependent shaking in mammals and birds.
Selescu T, Bivoleanu RA, Iodi Carstens M, Manolache A, Caragea VM, Hutanu DE, Meerupally R, Wei ET, Carstens E, Zimmermann K, Babes A. Selescu T, et al. Among authors: zimmermann k. bioRxiv [Preprint]. 2024 Jan 16:2023.12.27.573364. doi: 10.1101/2023.12.27.573364. bioRxiv. 2024. PMID: 38234797 Free PMC article. Preprint.
80 results