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3D reconstruction of murine mitochondria reveals changes in structure during aging linked to the MICOS complex.
Vue Z, Garza-Lopez E, Neikirk K, Katti P, Vang L, Beasley H, Shao J, Marshall AG, Crabtree A, Murphy AC, Jenkins BC, Prasad P, Evans C, Taylor B, Mungai M, Killion M, Stephens D, Christensen TA, Lam J, Rodriguez B, Phillips MA, Daneshgar N, Koh HJ, Koh A, Davis J, Devine N, Saleem M, Scudese E, Arnold KR, Vanessa Chavarin V, Daniel Robinson R, Chakraborty M, Gaddy JA, Sweetwyne MT, Wilson G, Zaganjor E, Kezos J, Dondi C, Reddy AK, Glancy B, Kirabo A, Quintana AM, Dai DF, Ocorr K, Murray SA, Damo SM, Exil V, Riggs B, Mobley BC, Gomez JA, McReynolds MR, Hinton A Jr. Vue Z, et al. Aging Cell. 2023 Dec;22(12):e14009. doi: 10.1111/acel.14009. Epub 2023 Nov 13. Aging Cell. 2023. PMID: 37960952 Free PMC article.
Beyond Fixation: Persistent Genetic Variation Under Intense Selection.
Arnold KR, Greenspan ZS, Robinson RD, Pupo A, Chavarin VV, Chang KS, Cannell CO, Qi M, Mueller LD, Rose MR, Phillips MA. Arnold KR, et al. bioRxiv [Preprint]. 2026 Mar 31:2026.03.02.706684. doi: 10.64898/2026.03.02.706684. bioRxiv. 2026. PMID: 41867759 Free PMC article. Preprint.
Selection for early reproduction leads to accelerated aging and extensive metabolic remodeling in Drosophila melanogaster.
Hubert DL, Arnold KR, Greenspan ZS, Pupo A, Robinson RD, Chavarin VV, Barter TB, Djukovic D, Raftery D, Vue Z, Hinton A Jr, McReynolds MR, Harrison BR, Phillips MA. Hubert DL, et al. Among authors: arnold kr. bioRxiv [Preprint]. 2025 Mar 9:2024.06.28.601037. doi: 10.1101/2024.06.28.601037. bioRxiv. 2025. Update in: Genome Biol Evol. 2025 Apr 30;17(5):evaf082. doi: 10.1093/gbe/evaf082. PMID: 39005259 Free PMC article. Updated. Preprint.
Genomics of Early Cardiac Dysfunction and Mortality in Obese Drosophila melanogaster.
Kezos JN, Phillips MA, Thomas MD, Ewunkem AJ, Rutledge GA, Barter TT, Santos MA, Wong BD, Arnold KR, Humphrey LA, Yan A, Nouzille C, Sanchez I, Cabral LG, Bradley TJ, Mueller LD, Graves JL Jr, Rose MR. Kezos JN, et al. Among authors: arnold kr. Physiol Biochem Zool. 2019 Nov/Dec;92(6):591-611. doi: 10.1086/706099. Physiol Biochem Zool. 2019. PMID: 31603376