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The Role of AMPK Activation for Cardioprotection in Doxorubicin-Induced Cardiotoxicity.

Timm KN, Tyler DJ. Timm KN, et al. Cardiovasc Drugs Ther. 2020 Apr;34(2):255-269. doi: 10.1007/s10557-020-06941-x. Cardiovasc Drugs Ther. 2020. PMID: 32034646 Free PMC article. Review.

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Cardiac applications of hyperpolarised magnetic resonance.

Timm KN, Miller JJ, Henry JA, Tyler DJ. Timm KN, et al. Prog Nucl Magn Reson Spectrosc. 2018 Jun-Aug;106-107:66-87. doi: 10.1016/j.pnmrs.2018.05.002. Epub 2018 May 31. Prog Nucl Magn Reson Spectrosc. 2018. PMID: 31047602 Review.

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A 3D hybrid-shot spiral sequence for hyperpolarized ${}^{13}C$ imaging.

Tyler A, Lau JYC, Ball V, Timm KN, Zhou T, Tyler DJ, Miller JJ. Tyler A, et al. Among authors: timm kn. Magn Reson Med. 2021 Feb;85(2):790-801. doi: 10.1002/mrm.28462. Epub 2020 Sep 7. Magn Reson Med. 2021. PMID: 32894618 Free PMC article.

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Cancer Therapy-Induced Cardiotoxicity-A Metabolic Perspective on Pathogenesis, Diagnosis and Therapy.

Choksey A, Timm KN. Choksey A, et al. Among authors: timm kn. Int J Mol Sci. 2021 Dec 31;23(1):441. doi: 10.3390/ijms23010441. Int J Mol Sci. 2021. PMID: 35008867 Free PMC article. Review.

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Imaging Tumor Metabolism to Assess Disease Progression and Treatment Response.

Timm KN, Kennedy BW, Brindle KM. Timm KN, et al. Clin Cancer Res. 2016 Nov 1;22(21):5196-5203. doi: 10.1158/1078-0432.CCR-16-0159. Epub 2016 Sep 8. Clin Cancer Res. 2016. PMID: 27609841 Free PMC article. Review.

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Probing hepatic metabolism of [2-¹³C]dihydroxyacetone in vivo with ¹H-decoupled hyperpolarized ¹³C-MR.

Marco-Rius I, Wright AJ, Hu DE, Savic D, Miller JJ, Timm KN, Tyler D, Brindle KM, Comment A. Marco-Rius I, et al. Among authors: timm kn. MAGMA. 2021 Feb;34(1):49-56. doi: 10.1007/s10334-020-00884-y. Epub 2020 Sep 10. MAGMA. 2021. PMID: 32910316 Free PMC article.

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Nicotinic acid receptor agonists impair myocardial contractility by energy starvation.

Watson WD, Timm KN, Lewis AJ, Miller JJJ, Emmanuel Y, Clarke K, Neubauer S, Tyler DJ, Rider OJ. Watson WD, et al. Among authors: timm kn. FASEB J. 2020 Nov;34(11):14878-14891. doi: 10.1096/fj.202000084RR. Epub 2020 Sep 21. FASEB J. 2020. PMID: 32954525

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Rapid, $B_1$ -insensitive, dual-band quasi-adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux.

Miller JJ, Valkovič L, Kerr M, Timm KN, Watson WD, Lau JYC, Tyler A, Rodgers C, Bottomley PA, Heather LC, Tyler DJ. Miller JJ, et al. Among authors: timm kn. Magn Reson Med. 2021 Jun;85(6):2978-2991. doi: 10.1002/mrm.28647. Epub 2021 Feb 3. Magn Reson Med. 2021. PMID: 33538063 Free PMC article.

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L-Carnitine Stimulates In Vivo Carbohydrate Metabolism in the Type 1 Diabetic Heart as Demonstrated by Hyperpolarized MRI.

Savic D, Ball V, Curtis MK, Sousa Fialho MDL, Timm KN, Hauton D, West J, Griffin J, Heather LC, Tyler DJ. Savic D, et al. Among authors: timm kn. Metabolites. 2021 Mar 23;11(3):191. doi: 10.3390/metabo11030191. Metabolites. 2021. PMID: 33806953 Free PMC article.

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Hyperpolarized magnetic resonance shows that the anti-ischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved post-ischemic function in the diabetic heart.

Savic D, Ball V, Holzner L, Hauton D, Timm KN, Curtis MK, Heather LC, Tyler DJ. Savic D, et al. Among authors: timm kn. NMR Biomed. 2021 Apr;34(4):e4471. doi: 10.1002/nbm.4471. Epub 2021 Jan 17. NMR Biomed. 2021. PMID: 33458907 Free PMC article.

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