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A research roadmap for next-generation sequencing informatics.

Altman RB, Prabhu S, Sidow A, Zook JM, Goldfeder R, Litwack D, Ashley E, Asimenos G, Bustamante CD, Donigan K, Giacomini KM, Johansen E, Khuri N, Lee E, Liang XS, Salit M, Serang O, Tezak Z, Wall DP, Mansfield E, Kass-Hout T. Altman RB, et al. Among authors: khuri n. Sci Transl Med. 2016 Apr 20;8(335):335ps10. doi: 10.1126/scitranslmed.aaf7314. Sci Transl Med. 2016. PMID: 27099173 Free PMC article. Review.

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Unmet needs: Research helps regulators do their jobs.

Altman RB, Khuri N, Salit M, Giacomini KM. Altman RB, et al. Among authors: khuri n. Sci Transl Med. 2015 Nov 25;7(315):315ps22. doi: 10.1126/scitranslmed.aac4369. Sci Transl Med. 2015. PMID: 26606966 Review.

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Molecular modeling and ligand docking for solute carrier (SLC) transporters.

Schlessinger A, Khuri N, Giacomini KM, Sali A. Schlessinger A, et al. Among authors: khuri n. Curr Top Med Chem. 2013;13(7):843-56. doi: 10.2174/1568026611313070007. Curr Top Med Chem. 2013. PMID: 23578028 Free PMC article. Review.

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Challenges in the Regulation of High-Cost Treatments: An Overview From Brazil.

Pereira LC, Sturzenegger DVR, Ortiz J, Ayad NME, Cortopassi WA, Safatle LP, Khuri N. Pereira LC, et al. Among authors: khuri n. Value Health Reg Issues. 2019 Dec;20:191-195. doi: 10.1016/j.vhri.2019.07.006. Epub 2019 Nov 13. Value Health Reg Issues. 2019. PMID: 31733406

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Interactions of Oral Molecular Excipients with Breast Cancer Resistance Protein, BCRP.

Zou L, Pottel J, Khuri N, Ngo HX, Ni Z, Tsakalozou E, Warren MS, Huang Y, Shoichet BK, Giacomini KM. Zou L, et al. Among authors: khuri n. Mol Pharm. 2020 Mar 2;17(3):748-756. doi: 10.1021/acs.molpharmaceut.9b00658. Epub 2020 Feb 10. Mol Pharm. 2020. PMID: 31990564 Free PMC article.

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Drug-nutrient interactions: discovering prescription drug inhibitors of the thiamine transporter ThTR-2 (SLC19A3).

Vora B, Green EAE, Khuri N, Ballgren F, Sirota M, Giacomini KM. Vora B, et al. Among authors: khuri n. Am J Clin Nutr. 2020 Jan 1;111(1):110-121. doi: 10.1093/ajcn/nqz255. Am J Clin Nutr. 2020. PMID: 31764942 Free PMC article.

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Global Protease Activity Profiling Identifies HER2-Driven Proteolysis in Breast Cancer.

Salcedo EC, Winter MB, Khuri N, Knudsen GM, Sali A, Craik CS. Salcedo EC, et al. Among authors: khuri n. ACS Chem Biol. 2021 Apr 16;16(4):712-723. doi: 10.1021/acschembio.0c01000. Epub 2021 Mar 25. ACS Chem Biol. 2021. PMID: 33765766

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Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives.

Zou L, Spanogiannopoulos P, Pieper LM, Chien HC, Cai W, Khuri N, Pottel J, Vora B, Ni Z, Tsakalozou E, Zhang W, Shoichet BK, Giacomini KM, Turnbaugh PJ. Zou L, et al. Among authors: khuri n. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16009-16018. doi: 10.1073/pnas.1920483117. Epub 2020 Jun 22. Proc Natl Acad Sci U S A. 2020. PMID: 32571913 Free PMC article.

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Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition.

Schneidman-Duhovny D, Khuri N, Dong GQ, Winter MB, Shifrut E, Friedman N, Craik CS, Pratt KP, Paz P, Aswad F, Sali A. Schneidman-Duhovny D, et al. Among authors: khuri n. PLoS One. 2018 Nov 6;13(11):e0206654. doi: 10.1371/journal.pone.0206654. eCollection 2018. PLoS One. 2018. PMID: 30399156 Free PMC article.

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Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1).

Chen EC, Khuri N, Liang X, Stecula A, Chien HC, Yee SW, Huang Y, Sali A, Giacomini KM. Chen EC, et al. Among authors: khuri n. J Med Chem. 2017 Apr 13;60(7):2685-2696. doi: 10.1021/acs.jmedchem.6b01317. Epub 2017 Mar 15. J Med Chem. 2017. PMID: 28230985 Free article.

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