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Oxygen concentration modulates cellular senescence and autophagy in human trophoblast cells.

Seno K, Tanikawa N, Takahashi H, Ohkuchi A, Suzuki H, Matsubara S, Iwata H, Kuwayama T, Shirasuna K. Seno K, et al. Am J Reprod Immunol. 2018 Jun;79(6):e12826. doi: 10.1111/aji.12826. Epub 2018 Feb 15. Am J Reprod Immunol. 2018. PMID: 29446169

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Olive Leaf Extract (OleaVita) Suppresses Inflammatory Cytokine Production and NLRP3 Inflammasomes in Human Placenta.

Kaneko Y, Sano M, Seno K, Oogaki Y, Takahashi H, Ohkuchi A, Yokozawa M, Yamauchi K, Iwata H, Kuwayama T, Shirasuna K. Kaneko Y, et al. Among authors: seno k. Nutrients. 2019 Apr 28;11(5):970. doi: 10.3390/nu11050970. Nutrients. 2019. PMID: 31035323 Free PMC article.

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Advanced glycation end products regulate interleukin-1β production in human placenta.

Seno K, Sase S, Ozeki A, Takahashi H, Ohkuchi A, Suzuki H, Matsubara S, Iwata H, Kuwayama T, Shirasuna K. Seno K, et al. J Reprod Dev. 2017 Aug 19;63(4):401-408. doi: 10.1262/jrd.2017-032. Epub 2017 May 18. J Reprod Dev. 2017. PMID: 28515391 Free PMC article.

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Aggregation of Human Trophoblast Cells into Three-Dimensional Culture System Enhances Anti-Inflammatory Characteristics through Cytoskeleton Regulation.

Seno K, Munakata Y, Sano M, Kawahara-Miki R, Takahashi H, Ohkuchi A, Iwata H, Kuwayama T, Shirasuna K. Seno K, et al. Int J Mol Sci. 2018 Aug 8;19(8):2322. doi: 10.3390/ijms19082322. Int J Mol Sci. 2018. PMID: 30096769 Free PMC article.

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Interferon Tau Regulates Cytokine Production and Cellular Function in Human Trophoblast Cell Line.

Tanikawa N, Seno K, Kawahara-Miki R, Kimura K, Matsuyama S, Iwata H, Kuwayama T, Shirasuna K. Tanikawa N, et al. Among authors: seno k. J Interferon Cytokine Res. 2017 Oct;37(10):456-466. doi: 10.1089/jir.2017.0057. J Interferon Cytokine Res. 2017. PMID: 29028431

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Palmitic acid stimulates interleukin-8 via the TLR4/NF-κB/ROS pathway and induces mitochondrial dysfunction in bovine oviduct epithelial cells.

Ohtsu A, Tanaka H, Seno K, Iwata H, Kuwayama T, Shirasuna K. Ohtsu A, et al. Among authors: seno k. Am J Reprod Immunol. 2017 Jun;77(6). doi: 10.1111/aji.12642. Epub 2017 Feb 10. Am J Reprod Immunol. 2017. PMID: 28185389

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Moderate Hypoxia Down-Regulates Interleukin-6 Secretion and TLR4 Expression in Human Sw.71 Placental Cells.

Shirasuna K, Shimamura N, Seno K, Ohtsu A, Shiratsuki S, Ohkuchi A, Suzuki H, Matsubara S, Nagayama S, Iwata H, Kuwayama T. Shirasuna K, et al. Among authors: seno k. Cell Physiol Biochem. 2015;36(6):2149-60. doi: 10.1159/000430181. Epub 2015 Jul 21. Cell Physiol Biochem. 2015. PMID: 26279422 Free article.

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AGEs and HMGB1 Increase Inflammatory Cytokine Production from Human Placental Cells, Resulting in an Enhancement of Monocyte Migration.

Shirasuna K, Seno K, Ohtsu A, Shiratsuki S, Ohkuchi A, Suzuki H, Matsubara S, Nagayama S, Iwata H, Kuwayama T. Shirasuna K, et al. Among authors: seno k. Am J Reprod Immunol. 2016 May;75(5):557-68. doi: 10.1111/aji.12506. Epub 2016 Mar 9. Am J Reprod Immunol. 2016. PMID: 26961863

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Palmitic acid induces interleukin-1β secretion via NLRP3 inflammasomes and inflammatory responses through ROS production in human placental cells.

Shirasuna K, Takano H, Seno K, Ohtsu A, Karasawa T, Takahashi M, Ohkuchi A, Suzuki H, Matsubara S, Iwata H, Kuwayama T. Shirasuna K, et al. Among authors: seno k. J Reprod Immunol. 2016 Aug;116:104-12. doi: 10.1016/j.jri.2016.06.001. Epub 2016 Jun 6. J Reprod Immunol. 2016. PMID: 27300134

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Advanced glycation end products and lipopolysaccharides stimulate interleukin-6 secretion via the RAGE/TLR4-NF-κB-ROS pathways and resveratrol attenuates these inflammatory responses in mouse macrophages.

Ohtsu A, Shibutani Y, Seno K, Iwata H, Kuwayama T, Shirasuna K. Ohtsu A, et al. Among authors: seno k. Exp Ther Med. 2017 Nov;14(5):4363-4370. doi: 10.3892/etm.2017.5045. Epub 2017 Aug 28. Exp Ther Med. 2017. PMID: 29067115 Free PMC article.

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