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Showing results for kristian driven
Your search for Kristian Drivenes retrieved no results
Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.
Nielsen JB, Thorolfsdottir RB, Fritsche LG, Zhou W, Skov MW, Graham SE, Herron TJ, McCarthy S, Schmidt EM, Sveinbjornsson G, Surakka I, Mathis MR, Yamazaki M, Crawford RD, Gabrielsen ME, Skogholt AH, Holmen OL, Lin M, Wolford BN, Dey R, Dalen H, Sulem P, Chung JH, Backman JD, Arnar DO, Thorsteinsdottir U, Baras A, O'Dushlaine C, Holst AG, Wen X, Hornsby W, Dewey FE, Boehnke M, Kheterpal S, Mukherjee B, Lee S, Kang HM, Holm H, Kitzman J, Shavit JA, Jalife J, Brummett CM, Teslovich TM, Carey DJ, Gudbjartsson DF, Stefansson K, Abecasis GR, Hveem K, Willer CJ. Nielsen JB, et al. Nat Genet. 2018 Sep;50(9):1234-1239. doi: 10.1038/s41588-018-0171-3. Epub 2018 Jul 30. Nat Genet. 2018. PMID: 30061737 Free PMC article.
Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing.
Bartoschek M, Oskolkov N, Bocci M, Lövrot J, Larsson C, Sommarin M, Madsen CD, Lindgren D, Pekar G, Karlsson G, Ringnér M, Bergh J, Björklund Å, Pietras K. Bartoschek M, et al. Nat Commun. 2018 Dec 4;9(1):5150. doi: 10.1038/s41467-018-07582-3. Nat Commun. 2018. PMID: 30514914 Free PMC article.
In conclusion, the improved resolution of the widely defined CAF population opens the possibility for biomarker-driven development of drugs for precision targeting of CAFs....
In conclusion, the improved resolution of the widely defined CAF population opens the possibility for biomarker-driven development of …
The Psychiatric Genomics Consortium: discoveries and directions.
Agrawal A, Bulik CM, Abebe DS, Andreassen OA, Atkinson EG, Choi KW, Corvin A, Davies HL, Davis LK, Docherty AR, Edenberg HJ, Franke B, Gelernter J, Giusti-Rodríguez P, Hettema JM, Hjerling-Leffler J, Huang H, Johnson EC, Lewis CM, Lu Y, Lynall ME, Martin J, McIntosh AM, Montalvo-Ortiz JL, Mullins N, Nievergelt CM, O'Connell KS, O'Donovan MC, Okewole A, Peterson RE, Posthuma D, Sebat J, Smoller JW, Sud R, Viswanath B, Walters JTR, Won H, Wray NR, Sullivan PF; Coordinating Committee of the Psychiatric Genomics Consortium. Agrawal A, et al. Lancet Psychiatry. 2025 Aug;12(8):600-610. doi: 10.1016/S2215-0366(25)00124-5. Epub 2025 Jun 26. Lancet Psychiatry. 2025. PMID: 40582370 Review.
Pericytes orchestrate a tumor-restraining microenvironment in glioblastoma.
Braun S, Bolivar P, Oudenaarden C, Sjölund J, Bocci M, Harbst K, Talkhoncheh MS, Phung B, Cordero E, Rosberg R, Johansson E, Jönsson GB, Pietras A, Pietras K. Braun S, et al. Nat Commun. 2025 Dec 4;16(1):10918. doi: 10.1038/s41467-025-66985-1. Nat Commun. 2025. PMID: 41339360 Free PMC article.
The recruited macrophages express Hepatocyte Growth Factor, which reinforces activation of its receptor tyrosine kinase MET on GBM cells harboring a pronounced mesenchymal subtype driven by the key phenotypic regulator Fosl1. Indeed, orthotopic implantation of MET-expressi …
The recruited macrophages express Hepatocyte Growth Factor, which reinforces activation of its receptor tyrosine kinase MET on GBM cells har …
Ex vivo stimulation of the trigeminal nucleus caudalis induces peripheral CGRP release in the trigeminal ganglion and reveals a distinct dopamine-endocannabinoid mechanism relevant to migraine.
Christiansen IM, Reducha PV, Edvinsson L, Holm A, Haanes KA. Christiansen IM, et al. J Headache Pain. 2025 Jun 16;26(1):141. doi: 10.1186/s10194-025-02072-6. J Headache Pain. 2025. PMID: 40524163 Free PMC article.
TRPV1 blockade or pharmacological inhibition of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD), an enzyme important for anandamide biosynthesis, markedly attenuated dopamine-induced CGRP release, indicating that an endocannabinoid-driven mechanism is involved. …
TRPV1 blockade or pharmacological inhibition of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD), an enzyme important for anandami …
Stealth nanorods via the aqueous living crystallisation-driven self-assembly of poly(2-oxazoline)s.
Finnegan JR, Pilkington EH, Alt K, Rahim MA, Kent SJ, Davis TP, Kempe K. Finnegan JR, et al. Chem Sci. 2021 Apr 12;12(21):7350-7360. doi: 10.1039/d1sc00938a. Chem Sci. 2021. PMID: 34163824 Free PMC article.
Here, we combine 'living' crystallisation-driven self-assembly (CDSA), a seeded growth method that enables the preparation of rod-like polymer nanoparticles, with poly(2-oxazoline)s (POx), a polymer class that exhibits 'stealth' behaviour and excellent biocompatibility. .. …
Here, we combine 'living' crystallisation-driven self-assembly (CDSA), a seeded growth method that enables the preparation of rod-lik …
Testosterone replacement therapy and the risk of venous thromboembolism: A systematic review and meta-analysis of randomized controlled trials.
Ayele HT, Brunetti VC, Renoux C, Tagalakis V, Filion KB. Ayele HT, et al. Thromb Res. 2021 Mar;199:123-131. doi: 10.1016/j.thromres.2020.12.029. Epub 2021 Jan 6. Thromb Res. 2021. PMID: 33486321
Five studies had a high risk of bias, largely driven by unclear randomization and outcome assessment. When data were pooled across RCTs, testosterone therapy was not associated with VTE compared with placebo (RR: 1.03, 95% CI: 0.49-2.14; I(2): 0%; low-quality evidence). .. …
Five studies had a high risk of bias, largely driven by unclear randomization and outcome assessment. When data were pooled across RC …
A Novel CDC42 Variant with Impaired Thymopoiesis, IL-7R Signaling, PAK1 Binding, and TCR Repertoire Diversity.
Assing K, Jørgensen SE, Sandgaard KS, De Keukeleere K, B-Hansen M, Petersen MS, Hartling UB, Vaal TMK, Nielsen C, Jakobsen MA, Watt E, Adams S, Hao Q, Fagerberg C, Mogensen TH. Assing K, et al. J Clin Immunol. 2023 Nov;43(8):1927-1940. doi: 10.1007/s10875-023-01561-0. Epub 2023 Aug 15. J Clin Immunol. 2023. PMID: 37581646 Free PMC article.
We report a novel CDC42 missense variant (c.46A > G, p.Lys16Glu) resulting in infection and HPV-driven carcinogenesis in the mosaic mother and impaired thymopoiesis and profound T cell lymphopenia in the heterozygous daughter identified through newborn screening for SCI …
We report a novel CDC42 missense variant (c.46A > G, p.Lys16Glu) resulting in infection and HPV-driven carcinogenesis in the mosai …
37 results