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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 2
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1984 1
1985 2
1986 1
1991 2
1992 1
1997 1
1999 1
2000 1
2002 1
2003 2
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2005 2
2006 1
2007 3
2008 1
2009 3
2010 1
2012 2
2013 1
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2017 1
2018 3
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2020 2
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43 results
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Filters applied: . Clear all The following term was not found in PubMed: Smerpitak
Page 1
KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell cell junctions.
Glading A, Han J, Stockton RA, Ginsberg MH. Glading A, et al. J Cell Biol. 2007 Oct 22;179(2):247-54. doi: 10.1083/jcb.200705175. J Cell Biol. 2007. PMID: 17954608 Free PMC article.
Cerebral cavernous malformation (CCM), a disease associated with defective endothelial junctions, result from autosomal dominant CCM1 mutations that cause loss of KRIT-1 protein function, though how the loss of KRIT-1 leads to CCM is obscure. ...Rap1 activity regula …
Cerebral cavernous malformation (CCM), a disease associated with defective endothelial junctions, result from autosomal dominant CCM1 mutati …
Control of cell adhesion dynamics by Rap1 signaling.
Boettner B, Van Aelst L. Boettner B, et al. Curr Opin Cell Biol. 2009 Oct;21(5):684-93. doi: 10.1016/j.ceb.2009.06.004. Epub 2009 Jul 16. Curr Opin Cell Biol. 2009. PMID: 19615876 Free PMC article. Review.
In this review we will discuss more recently revealed roles of Rap1 signaling by primarily focusing on functions of the Rap1 effectors RIAM, KRIT-1/CCM1 and AF-6/Afadin in junctional regulation of the vascular system and in epithelial cells. ...
In this review we will discuss more recently revealed roles of Rap1 signaling by primarily focusing on functions of the Rap1 effectors RIAM, …
[A novel Krit-1 mutation in Han family with cerebral cavernous malformation].
Xu YL, Zhao JZ, Wu BQ, Zhong HH, Wang S, Heng WJ. Xu YL, et al. Zhonghua Bing Li Xue Za Zhi. 2003 Jun;32(3):220-5. Zhonghua Bing Li Xue Za Zhi. 2003. PMID: 12882686 Chinese.
OBJECTIVE: To detect the mutations of Krit-1 gene that cause familial cerebral cavernous malformation (CCM) in the Han ethnic origin. ...Two families (A and B) and 8 apparently sporadic individuals affected with CCM were screened for mutations of Krit-1 gene. Member …
OBJECTIVE: To detect the mutations of Krit-1 gene that cause familial cerebral cavernous malformation (CCM) in the Han ethnic origin. …
CCM1 and the second life of proteins in adhesion complexes.
van den Berg MC, Burgering BM. van den Berg MC, et al. Cell Adh Migr. 2014;8(2):146-57. doi: 10.4161/cam.28437. Cell Adh Migr. 2014. PMID: 24714220 Free PMC article. Review.
Here we discuss nuclear functions of adhesion complex proteins with a special focus on the CCM-1/KRIT-1 protein, which may turn out to be yet another adhesion complex protein with a second life....
Here we discuss nuclear functions of adhesion complex proteins with a special focus on the CCM-1/KRIT-1 protein, which may turn out t …
Cell-cell junction formation: the role of Rap1 and Rap1 guanine nucleotide exchange factors.
Pannekoek WJ, Kooistra MR, Zwartkruis FJ, Bos JL. Pannekoek WJ, et al. Biochim Biophys Acta. 2009 Apr;1788(4):790-6. doi: 10.1016/j.bbamem.2008.12.010. Epub 2008 Dec 29. Biochim Biophys Acta. 2009. PMID: 19159611 Free article. Review.
Downstream of Rap, a number of effector proteins have been implicated in junctional control, most notably the adaptor proteins AF6 and KRIT/CCM1. In this review, we will highlight the latest findings on the Rap signaling network in the control of epithelial and endothelial …
Downstream of Rap, a number of effector proteins have been implicated in junctional control, most notably the adaptor proteins AF6 and KR
Inherited cavernous malformations of the central nervous system: clinical and genetic features in 19 Swiss families.
Graeni C, Stepper F, Sturzenegger M, Merlo A, Verlaan DJ, Andermann F, Baumann CR, Bonassin F, Georgiadis D, Baumgartner RW, Rouleau GA, Siegel AM. Graeni C, et al. Neurosurg Rev. 2010 Jan;33(1):47-51. doi: 10.1007/s10143-009-0225-1. Epub 2009 Sep 17. Neurosurg Rev. 2010. PMID: 19760287
The familiar form is associated with three gene loci, namely 7q21-q22 (CCM1), 7p13-p15 (CCM2), and 3q25.2-q27 (CCM3) and is inherited as an autosomal dominant trait with incomplete penetrance. The CCM genes are identified as Krit 1 (CCM1), MGC4607 (CCM2), and PDCD10 (CCM3) …
The familiar form is associated with three gene loci, namely 7q21-q22 (CCM1), 7p13-p15 (CCM2), and 3q25.2-q27 (CCM3) and is inherited as an …
43 results
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