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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1985 2
1986 1
1989 3
1991 3
1992 3
1994 1
1995 3
1996 2
2000 1
2001 3
2003 1
2004 1
2005 3
2006 4
2007 4
2008 2
2009 3
2010 1
2012 1
2015 3
2016 5
2017 4
2018 2
2021 1
2022 2
2023 0
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55 results
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Page 1
Discovery of a Partial Glucokinase Activator Clinical Candidate: Diethyl ((3-(3-((5-(Azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)-1H-pyrazol-1-yl)methyl)phosphonate (BMS-820132).
Shi Y, Wang Y, Meng W, Brigance RP, Ryono DE, Bolton S, Zhang H, Chen S, Smirk R, Tao S, Tino JA, Williams KN, Sulsky R, Nielsen L, Ellsworth B, Wong MKY, Sun JH, Leith LW, Sun D, Wu DR, Gupta A, Rampulla R, Mathur A, Chen BC, Wang A, Fuentes-Catanio HG, Kunselman L, Cap M, Zalaznick J, Ma X, Liu H, Taylor JR, Zebo R, Jones B, Kalinowski S, Swartz J, Staal A, O'Malley K, Kopcho L, Muckelbauer JK, Krystek SR Jr, Spronk SA, Marcinkeviciene J, Everlof G, Chen XQ, Xu C, Li YX, Langish RA, Yang Y, Wang Q, Behnia K, Fura A, Janovitz EB, Pannacciulli N, Griffen S, Zinker BA, Krupinski J, Kirby M, Whaley J, Zahler R, Barrish JC, Robl JA, Cheng PTW. Shi Y, et al. Among authors: krystek sr jr. J Med Chem. 2022 Mar 10;65(5):4291-4317. doi: 10.1021/acs.jmedchem.1c02110. Epub 2022 Feb 18. J Med Chem. 2022. PMID: 35179904
Mutational analysis of the endothelin type A receptor (ETA): interactions and model of selective ETA antagonist BMS-182874 with putative ETA receptor binding cavity.
Webb ML, Patel PS, Rose PM, Liu EC, Stein PD, Barrish J, Lach DA, Stouch T, Fisher SM, Hadjilambris O, Lee H, Skwish S, Dickinson KE, Krystek SR Jr. Webb ML, et al. Among authors: krystek sr jr. Biochemistry. 1996 Feb 27;35(8):2548-56. doi: 10.1021/bi951836v. Biochemistry. 1996. PMID: 8611558
Protein secondary structure prediction.
Krystek SR Jr, Metzler WJ, Novotny J. Krystek SR Jr, et al. Curr Protoc Protein Sci. 2001 May;Chapter 2:Unit2.3. doi: 10.1002/0471140864.ps0203s00. Curr Protoc Protein Sci. 2001. PMID: 18429151
Structures of adnectin/protein complexes reveal an expanded binding footprint.
Ramamurthy V, Krystek SR Jr, Bush A, Wei A, Emanuel SL, Das Gupta R, Janjua A, Cheng L, Murdock M, Abramczyk B, Cohen D, Lin Z, Morin P, Davis JH, Dabritz M, McLaughlin DC, Russo KA, Chao G, Wright MC, Jenny VA, Engle LJ, Furfine E, Sheriff S. Ramamurthy V, et al. Among authors: krystek sr jr. Structure. 2012 Feb 8;20(2):259-69. doi: 10.1016/j.str.2011.11.016. Structure. 2012. PMID: 22325775 Free article.
Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope.
Yamniuk AP, Suri A, Krystek SR, Tamura J, Ramamurthy V, Kuhn R, Carroll K, Fleener C, Ryseck R, Cheng L, An Y, Drew P, Grant S, Suchard SJ, Nadler SG, Bryson JW, Sheriff S. Yamniuk AP, et al. Among authors: krystek sr. J Mol Biol. 2016 Jul 17;428(14):2860-79. doi: 10.1016/j.jmb.2016.05.014. Epub 2016 May 21. J Mol Biol. 2016. PMID: 27216500 Free article.
Biotechnology Based Process for Production of a Disulfide-Bridged Peptide.
Goswami A, Goldberg SL, Hanson RL, Johnston RM, Lyngberg OK, Chan Y, Lo E, Chan SH, de Mas N, Ramirez A, Doyle R, Ding W, Gao M, Krystek SR Jr, Wan C, Kim YJ, Calambur D, Witmer M, Bryson JW. Goswami A, et al. Among authors: krystek sr jr. Bioconjug Chem. 2016 May 18;27(5):1276-84. doi: 10.1021/acs.bioconjchem.6b00101. Epub 2016 May 2. Bioconjug Chem. 2016. PMID: 27098672
Discovery and Preclinical Evaluation of BMS-711939, an Oxybenzylglycine Based PPARα Selective Agonist.
Shi Y, Li J, Kennedy LJ, Tao S, Hernández AS, Lai Z, Chen S, Wong H, Zhu J, Trehan A, Lim NK, Zhang H, Chen BC, Locke KT, O'Malley KM, Zhang L, Srivastava RA, Miao B, Meyers DS, Monshizadegan H, Search D, Grimm D, Zhang R, Harrity T, Kunselman LK, Cap M, Muckelbauer J, Chang C, Krystek SR, Li YX, Hosagrahara V, Zhang L, Kadiyala P, Xu C, Blanar MA, Zahler R, Mukherjee R, Cheng PT, Tino JA. Shi Y, et al. Among authors: krystek sr. ACS Med Chem Lett. 2016 Apr 4;7(6):590-4. doi: 10.1021/acsmedchemlett.6b00033. eCollection 2016 Jun 9. ACS Med Chem Lett. 2016. PMID: 27326332 Free PMC article.
55 results