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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1943 1
1947 2
1950 1
1951 1
1953 1
1954 3
1955 1
1956 3
1957 5
1958 8
1959 8
1960 4
1961 9
1962 13
1963 14
1964 18
1965 19
1966 23
1967 19
1968 32
1969 39
1970 40
1971 50
1972 60
1973 97
1974 79
1975 112
1976 164
1977 189
1978 185
1979 236
1980 229
1981 277
1982 288
1983 352
1984 361
1985 406
1986 447
1987 504
1988 527
1989 678
1990 686
1991 910
1992 1380
1993 1607
1994 1881
1995 1991
1996 2284
1997 2548
1998 2899
1999 3491
2000 4170
2001 5195
2002 5654
2003 6299
2004 6756
2005 6860
2006 6916
2007 7708
2008 8997
2009 9504
2010 10433
2011 11440
2012 12193
2013 12138
2014 12938
2015 13763
2016 13785
2017 13944
2018 14080
2019 14337
2020 15631
2021 5670
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218,984 results
Results by year
Filters applied: . Clear all The following term was not found in PubMed: Kwan-Yuhl
Page 1
Carbohydrate intake during exercise and performance.
Jeukendrup AE. Jeukendrup AE. Nutrition. 2004 Jul-Aug;20(7-8):669-77. doi: 10.1016/j.nut.2004.04.017. Nutrition. 2004. PMID: 15212750 Review.
An analysis of all studies available shows that a single CHO ingested during exercise will be oxidized at rates up to about 1 g/min, even when large amounts of CHO are ingested. Combinations of CHO that use different intestinal transporters for absorption (e. …
An analysis of all studies available shows that a single CHO ingested during exercise will be oxidized at rates up to about 1 g/min, …
Bioprocessing of Recombinant CHO-K1, CHO-DG44, and CHO-S: CHO Expression Hosts Favor Either mAb Production or Biomass Synthesis.
Reinhart D, Damjanovic L, Kaisermayer C, Sommeregger W, Gili A, Gasselhuber B, Castan A, Mayrhofer P, Grünwald-Gruber C, Kunert R. Reinhart D, et al. Biotechnol J. 2019 Mar;14(3):e1700686. doi: 10.1002/biot.201700686. Epub 2018 Jun 11. Biotechnol J. 2019. PMID: 29701329
Chinese hamster ovary (CHO) cells comprise a variety of lineages including CHO-DXB11, CHO-K1, CHO-DG44, and CHO-S. ...However, not much literature is available about the influence of genetic differences of CHO on the performance of biopro …
Chinese hamster ovary (CHO) cells comprise a variety of lineages including CHO-DXB11, CHO-K1, CHO-DG44, and C …
The art of CHO cell engineering: A comprehensive retrospect and future perspectives.
Fischer S, Handrick R, Otte K. Fischer S, et al. Biotechnol Adv. 2015 Dec;33(8):1878-96. doi: 10.1016/j.biotechadv.2015.10.015. Epub 2015 Oct 31. Biotechnol Adv. 2015. PMID: 26523782 Review.
Chinese hamster ovary (CHO) cells represent the most frequently applied host cell system for industrial manufacturing of recombinant protein therapeutics. CHO cells are capable of producing high quality biologics exhibiting human-like post-translational modification …
Chinese hamster ovary (CHO) cells represent the most frequently applied host cell system for industrial manufacturing of recombinant …
Cell engineering and cultivation of chinese hamster ovary (CHO) cells.
Omasa T, Onitsuka M, Kim WD. Omasa T, et al. Curr Pharm Biotechnol. 2010 Apr;11(3):233-40. doi: 10.2174/138920110791111960. Curr Pharm Biotechnol. 2010. PMID: 20210750 Review.
The CHO-based cultivation process is well established and is a general platform of therapeutic antibody production. ...This review provides an overview of the industrial production of therapeutic proteins using a CHO cell expression system....
The CHO-based cultivation process is well established and is a general platform of therapeutic antibody production. ...This review pr …
CHO-Omics Review: The Impact of Current and Emerging Technologies on Chinese Hamster Ovary Based Bioproduction.
Stolfa G, Smonskey MT, Boniface R, Hachmann AB, Gulde P, Joshi AD, Pierce AP, Jacobia SJ, Campbell A. Stolfa G, et al. Biotechnol J. 2018 Mar;13(3):e1700227. doi: 10.1002/biot.201700227. Epub 2017 Nov 15. Biotechnol J. 2018. PMID: 29072373 Review.
CHO cells are the most prevalent platform for modern bio-therapeutic production. Currently, there are several CHO cell lines used in bioproduction with distinct characteristics and unique genotypes and phenotypes. ...
CHO cells are the most prevalent platform for modern bio-therapeutic production. Currently, there are several CHO cell lines u …
A high density CHO-S transient transfection system: Comparison of ExpiCHO and Expi293.
Jain NK, Barkowski-Clark S, Altman R, Johnson K, Sun F, Zmuda J, Liu CY, Kita A, Schulz R, Neill A, Ballinger R, Patel R, Liu J, Mpanda A, Huta B, Chiou H, Voegtli W, Panavas T. Jain NK, et al. Protein Expr Purif. 2017 Jun;134:38-46. doi: 10.1016/j.pep.2017.03.018. Epub 2017 Mar 23. Protein Expr Purif. 2017. PMID: 28342833
Chinese Hamster Ovary (CHO) cells are the principal mammalian host used for stable cell line generation and biotherapeutic protein production. ...Therefore, it is potentially advantageous to keep the host cell type consistent throughout drug discovery and development. To t …
Chinese Hamster Ovary (CHO) cells are the principal mammalian host used for stable cell line generation and biotherapeutic protein pr …
The fickle CHO: a review of the causes, implications, and potential alleviation of the CHO cell line instability problem.
Dahodwala H, Lee KH. Dahodwala H, et al. Curr Opin Biotechnol. 2019 Dec;60:128-137. doi: 10.1016/j.copbio.2019.01.011. Epub 2019 Feb 28. Curr Opin Biotechnol. 2019. PMID: 30826670 Review.
Chinese hamster ovary (CHO) cell-based bioproduction of recombinant proteins can now routinely achieve >5 g/L titers in fed-batches. This progress is partly due to the rapid adaptability of CHO cells to various genetic manipulations and changing process condition …
Chinese hamster ovary (CHO) cell-based bioproduction of recombinant proteins can now routinely achieve >5 g/L titers in fed-batche …
Improving the efficiency of CHO cell line generation using glutamine synthetase gene knockout cells.
Fan L, Kadura I, Krebs LE, Hatfield CC, Shaw MM, Frye CC. Fan L, et al. Biotechnol Bioeng. 2012 Apr;109(4):1007-15. doi: 10.1002/bit.24365. Epub 2011 Nov 21. Biotechnol Bioeng. 2012. PMID: 22068567
Although Chinese hamster ovary (CHO) cells, with their unique characteristics, have become a major workhorse for the manufacture of therapeutic recombinant proteins, one of the major challenges in CHO cell line generation (CLG) is how to efficiently identify those r …
Although Chinese hamster ovary (CHO) cells, with their unique characteristics, have become a major workhorse for the manufacture of t …
De novo lipogenesis in humans: metabolic and regulatory aspects.
Hellerstein MK. Hellerstein MK. Eur J Clin Nutr. 1999 Apr;53 Suppl 1:S53-65. doi: 10.1038/sj.ejcn.1600744. Eur J Clin Nutr. 1999. PMID: 10365981 Review.
The enzymatic pathway for converting dietary carbohydrate (CHO) into fat, or de novo lipogenesis (DNL), is present in humans, whereas the capacity to convert fats into CHO does not exist. ...Similarly, addition of CHO to a mixed diet does not increase hepatic …
The enzymatic pathway for converting dietary carbohydrate (CHO) into fat, or de novo lipogenesis (DNL), is present in humans, whereas …
Fat adaptation in well-trained athletes: effects on cell metabolism.
Yeo WK, Carey AL, Burke L, Spriet LL, Hawley JA. Yeo WK, et al. Appl Physiol Nutr Metab. 2011 Feb;36(1):12-22. doi: 10.1139/H10-089. Appl Physiol Nutr Metab. 2011. PMID: 21326374 Review.
One such strategy is "fat adaptation", an intervention in which well-trained endurance athletes consume a high-fat, low-CHO diet for up to 2 weeks while undertaking their normal training and then immediately follow this by CHO restoration (consuming a high-CHO …
One such strategy is "fat adaptation", an intervention in which well-trained endurance athletes consume a high-fat, low-CHO diet for …
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