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1969 1
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1993 1
1994 2
1995 1
1996 1
1999 2
2001 1
2002 4
2003 1
2004 3
2005 1
2006 2
2007 1
2008 4
2009 1
2010 2
2011 5
2012 5
2013 3
2014 4
2015 5
2016 7
2017 9
2018 7
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80 results

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Page 1
Advanced glycosidases as ingenious biosynthetic instruments.
Mészáros Z, Nekvasilová P, Bojarová P, Křen V, Slámová K. Mészáros Z, et al. Biotechnol Adv. 2021 Jul-Aug;49:107733. doi: 10.1016/j.biotechadv.2021.107733. Epub 2021 Mar 27. Biotechnol Adv. 2021. PMID: 33781890 Review.
The silymarin composition… and why does it matter???
Chambers CS, Holečková V, Petrásková L, Biedermann D, Valentová K, Buchta M, Křen V. Chambers CS, et al. Food Res Int. 2017 Oct;100(Pt 3):339-353. doi: 10.1016/j.foodres.2017.07.017. Epub 2017 Jul 12. Food Res Int. 2017. PMID: 28964357 Review.
The extract from milk thistle (Silybum marianum (L.) Gaertn. (Asteraceae)), known as silymarin, contains a variety of flavonolignans and displays antioxidant, anti-inflammatory, immunomodulatory and hepatoprotective properties. ...
The extract from milk thistle (Silybum marianum (L.) Gaertn. (Asteraceae)), known as silymarin, contains a variety of flavonolignans …
Isoquercitrin: pharmacology, toxicology, and metabolism.
Valentová K, Vrba J, Bancířová M, Ulrichová J, Křen V. Valentová K, et al. Food Chem Toxicol. 2014 Jun;68:267-82. doi: 10.1016/j.fct.2014.03.018. Epub 2014 Mar 27. Food Chem Toxicol. 2014. PMID: 24680690 Review.
Pure isoquercitrin can now be obtained on a large scale by enzymatic rutin hydrolysis with alpha-l-rhamnosidase. Isoquercitrin has higher bioavailability than quercetin and displays a number of chemoprotective effects both in vitro and in vivo, against oxidative stress, ca …
Pure isoquercitrin can now be obtained on a large scale by enzymatic rutin hydrolysis with alpha-l-rhamnosidase. Isoquercitrin has hi …
Rutinosidase and other diglycosidases: Rising stars in biotechnology.
Křen V, Bojarová P. Křen V, et al. Biotechnol Adv. 2023 Nov;68:108217. doi: 10.1016/j.biotechadv.2023.108217. Epub 2023 Jul 20. Biotechnol Adv. 2023. PMID: 37481095 Review.
The main diglycosidase representatives comprise rutinosidases that cleave rutinose (alpha-l-Rha-(1-6)-beta-d-Glc) from rutin or other rutinosides, and (iso)primeverosidases processing (iso)primeverosides (d-Xyl-(1-6)-beta-d-Glc), but other activities are known. ...
The main diglycosidase representatives comprise rutinosidases that cleave rutinose (alpha-l-Rha-(1-6)-beta-d-Glc) from rutin or other …
Crystal structure of native alpha-L-rhamnosidase from Aspergillus terreus.
Pachl P, Škerlová J, Šimčíková D, Kotik M, Křenková A, Mader P, Brynda J, Kapešová J, Křen V, Otwinowski Z, Řezáčová P. Pachl P, et al. Acta Crystallogr D Struct Biol. 2018 Nov 1;74(Pt 11):1078-1084. doi: 10.1107/S2059798318013049. Epub 2018 Oct 29. Acta Crystallogr D Struct Biol. 2018. PMID: 30387766
alpha-L-Rhamnosidases cleave terminal nonreducing alpha-L-rhamnosyl residues from many natural rhamnoglycosides. This makes them catalysts of interest for various biotechnological applications. The X-ray structure of the GH78 family alpha-L-rhamnosidase from …
alpha-L-Rhamnosidases cleave terminal nonreducing alpha-L-rhamnosyl residues from many natural rhamnoglycosides. This makes th …
[Passion Flower (Passiflora incarnata L.)--a reliable herbal sedative].
Krenn L. Krenn L. Wien Med Wochenschr. 2002;152(15-16):404-6. doi: 10.1046/j.1563-258x.2002.02062.x. Wien Med Wochenschr. 2002. PMID: 12244887 Review. German.
Extracts and fluid extracts from the aerial parts from Passiflora incarnata L. are widely used as components of herbal sedatives. Many pharmacological investigations confirm the sedative effects of Passiflorae herba. ...
Extracts and fluid extracts from the aerial parts from Passiflora incarnata L. are widely used as components of herbal sedatives. Man …
Chemoenzymatic synthesis of alpha-L-rhamnosides using recombinant alpha-L-rhamnosidase from Aspergillus terreus.
De Winter K, Šimčíková D, Schalck B, Weignerová L, Pelantova H, Soetaert W, Desmet T, Křen V. De Winter K, et al. Bioresour Technol. 2013 Nov;147:640-644. doi: 10.1016/j.biortech.2013.08.083. Epub 2013 Aug 23. Bioresour Technol. 2013. PMID: 24012095
This study describes an efficient, large scale fermentation of a recombinant alpha-L-rhamnosidase originating from Aspergillus terreus. High-cell-density Pichia pastoris fermentation resulted in yields up to 627 U/L/h. ...Careful optimization of these parameters all …
This study describes an efficient, large scale fermentation of a recombinant alpha-L-rhamnosidase originating from Aspergillus terreu …
80 results