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Unraveling the Antihyperglycemic Effects of Dipeptyl Peptidase-4 Inhibitors in Rodents: A Multi-Faceted Approach Combining Effects on Glucose Homeostasis, Molecular Docking, and ADMET Profiling.
Roriz RNS, Cardozo CJP, Freire GA, Martins CBR, Filho RRBX, Pereira LL, Rangel GFP, Sampaio TL, Ribeiro LR, Silva GS, Maia I, Wong DVT, Sousa DOB, de Oliveira AC, Reina E, Lima LM, Peláez W, da Rocha MN, Marinho MM, Santos HSD, Marinho ES, de Menezes JESA, Silva FRMB, Canuto KM, Alencar NMN, Frederico MJS. Roriz RNS, et al. Among authors: pereira ll. Pharmaceuticals (Basel). 2025 Oct 21;18(10):1589. doi: 10.3390/ph18101589. Pharmaceuticals (Basel). 2025. PMID: 41155701 Free PMC article.
LASSBio-1986 as a Multifunctional Antidiabetic Lead: SGLT1/2 Docking, Redox-Inflammatory Modulation and Metabolic Benefits in C57BL/6 Mice.
Pereira LL, Filho RRBX, Freire GA, Martins CBR, Perote MGB, Campos CLM, Monteiro MCS, Maia IFVC, Lacerda RB, Gelves LGV, Sousa DS, Souza RKB, Nunes PIG, Sampaio TL, Silva GS, Wong DVT, Lima LM, Peláez WJ, Marinho MM, Santos HSD, Menezes JESA, Marinho ES, Canuto KM, Souza PFN, Morais FS, Alencar NMN, Frederico MJS. Pereira LL, et al. Int J Mol Sci. 2026 Jan 14;27(2):829. doi: 10.3390/ijms27020829. Int J Mol Sci. 2026. PMID: 41596477 Free PMC article.