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2019 4
2020 1
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Page 1
Silibinin is a direct inhibitor of STAT3.
Verdura S, Cuyàs E, Llorach-Parés L, Pérez-Sánchez A, Micol V, Nonell-Canals A, Joven J, Valiente M, Sánchez-Martínez M, Bosch-Barrera J, Menendez JA. Verdura S, et al. Among authors: llorach pares l. Food Chem Toxicol. 2018 Jun;116(Pt B):161-172. doi: 10.1016/j.fct.2018.04.028. Epub 2018 Apr 14. Food Chem Toxicol. 2018. PMID: 29660364
Metformin directly targets the H3K27me3 demethylase KDM6A/UTX.
Cuyàs E, Verdura S, Llorach-Pares L, Fernández-Arroyo S, Luciano-Mateo F, Cabré N, Stursa J, Werner L, Martin-Castillo B, Viollet B, Neuzil J, Joven J, Nonell-Canals A, Sanchez-Martinez M, Menendez JA. Cuyàs E, et al. Among authors: llorach pares l. Aging Cell. 2018 Aug;17(4):e12772. doi: 10.1111/acel.12772. Epub 2018 May 8. Aging Cell. 2018. PMID: 29740925 Free PMC article.
Extra Virgin Olive Oil Contains a Phenolic Inhibitor of the Histone Demethylase LSD1/KDM1A.
Cuyàs E, Gumuzio J, Lozano-Sánchez J, Carreras D, Verdura S, Llorach-Parés L, Sanchez-Martinez M, Selga E, Pérez GJ, Scornik FS, Brugada R, Bosch-Barrera J, Segura-Carretero A, Martin ÁG, Encinar JA, Menendez JA. Cuyàs E, et al. Among authors: llorach pares l. Nutrients. 2019 Jul 19;11(7):1656. doi: 10.3390/nu11071656. Nutrients. 2019. PMID: 31331073 Free PMC article.
Metformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation.
Cuyàs E, Verdura S, Llorach-Parés L, Fernández-Arroyo S, Joven J, Martin-Castillo B, Bosch-Barrera J, Brunet J, Nonell-Canals A, Sanchez-Martinez M, Menendez JA. Cuyàs E, et al. Among authors: llorach pares l. Front Endocrinol (Lausanne). 2018 Nov 6;9:657. doi: 10.3389/fendo.2018.00657. eCollection 2018. Front Endocrinol (Lausanne). 2018. PMID: 30459716 Free PMC article.
Kororamides, Convolutamines, and Indole Derivatives as Possible Tau and Dual-Specificity Kinase Inhibitors for Alzheimer's Disease: A Computational Study.
Llorach-Pares L, Nonell-Canals A, Avila C, Sanchez-Martinez M. Llorach-Pares L, et al. Mar Drugs. 2018 Oct 16;16(10):386. doi: 10.3390/md16100386. Mar Drugs. 2018. PMID: 30332805 Free PMC article.
An olive oil phenolic is a new chemotype of mutant isocitrate dehydrogenase 1 (IDH1) inhibitors.
Verdura S, Cuyàs E, Lozano-Sánchez J, Bastidas-Velez C, Llorach-Parés L, Fernández-Arroyo S, Hernández-Aguilera A, Joven J, Nonell-Canals A, Bosch-Barrera J, Martin-Castillo B, Vellon L, Sanchez-Martinez M, Segura-Carretero A, Menendez JA. Verdura S, et al. Among authors: llorach pares l. Carcinogenesis. 2019 Mar 12;40(1):27-40. doi: 10.1093/carcin/bgy159. Carcinogenesis. 2019. PMID: 30428017
The extra virgin olive oil phenolic oleacein is a dual substrate-inhibitor of catechol-O-methyltransferase.
Cuyàs E, Verdura S, Lozano-Sánchez J, Viciano I, Llorach-Parés L, Nonell-Canals A, Bosch-Barrera J, Brunet J, Segura-Carretero A, Sanchez-Martinez M, Encinar JA, Menendez JA. Cuyàs E, et al. Among authors: llorach pares l. Food Chem Toxicol. 2019 Jun;128:35-45. doi: 10.1016/j.fct.2019.03.049. Epub 2019 Mar 29. Food Chem Toxicol. 2019. PMID: 30935952
Computational de-orphanization of the olive oil biophenol oleacein: Discovery of new metabolic and epigenetic targets.
Cuyàs E, Castillo D, Llorach-Parés L, Lozano-Sánchez J, Verdura S, Nonell-Canals A, Brunet J, Bosch-Barrera J, Joven J, Valdés R, Sanchez-Martinez M, Segura-Carretero A, Menendez JA. Cuyàs E, et al. Among authors: llorach pares l. Food Chem Toxicol. 2019 Sep;131:110529. doi: 10.1016/j.fct.2019.05.037. Epub 2019 May 29. Food Chem Toxicol. 2019. PMID: 31150784
Meridianins and Lignarenone B as Potential GSK3β Inhibitors and Inductors of Structural Neuronal Plasticity.
Llorach-Pares L, Rodriguez-Urgelles E, Nonell-Canals A, Alberch J, Avila C, Sanchez-Martinez M, Giralt A. Llorach-Pares L, et al. Biomolecules. 2020 Apr 21;10(4):639. doi: 10.3390/biom10040639. Biomolecules. 2020. PMID: 32326204 Free PMC article.
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