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Proteogenomic Analysis Identifies a Novel Human SHANK3 Isoform.

Benthani F, Tran PN, Currey N, Ng I, Giry-Laterriere M, Carey L, Kohonen-Corish MR, Pangon L. Benthani F, et al. Among authors: pangon l. Int J Mol Sci. 2015 May 19;16(5):11522-30. doi: 10.3390/ijms160511522. Int J Mol Sci. 2015. PMID: 25997006 Free PMC article.

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Sulindac activates NF-κB signaling in colon cancer cells.

Mladenova D, Pangon L, Currey N, Ng I, Musgrove EA, Grey ST, Kohonen-Corish MR. Mladenova D, et al. Among authors: pangon l. Cell Commun Signal. 2013 Oct 1;11:73. doi: 10.1186/1478-811X-11-73. Cell Commun Signal. 2013. PMID: 24083678 Free PMC article.

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Mutated in colorectal cancer protein modulates the NFκB pathway.

Sigglekow ND, Pangon L, Brummer T, Molloy M, Hawkins NJ, Ward RL, Musgrove EA, Kohonen-Corish MR. Sigglekow ND, et al. Among authors: pangon l. Anticancer Res. 2012 Jan;32(1):73-9. Anticancer Res. 2012. PMID: 22213290

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MCC inhibits beta-catenin transcriptional activity by sequestering DBC1 in the cytoplasm.

Pangon L, Mladenova D, Watkins L, Van Kralingen C, Currey N, Al-Sohaily S, Lecine P, Borg JP, Kohonen-Corish MR. Pangon L, et al. Int J Cancer. 2015 Jan 1;136(1):55-64. doi: 10.1002/ijc.28967. Epub 2014 May 27. Int J Cancer. 2015. PMID: 24824780 Free article.

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HIF1α deficiency reduces inflammation in a mouse model of proximal colon cancer.

Mladenova DN, Dahlstrom JE, Tran PN, Benthani F, Bean EG, Ng I, Pangon L, Currey N, Kohonen-Corish MR. Mladenova DN, et al. Among authors: pangon l. Dis Model Mech. 2015 Sep;8(9):1093-103. doi: 10.1242/dmm.019000. Epub 2015 Jul 16. Dis Model Mech. 2015. PMID: 26183215 Free PMC article.

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The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress.

Morris JR, Boutell C, Keppler M, Densham R, Weekes D, Alamshah A, Butler L, Galanty Y, Pangon L, Kiuchi T, Ng T, Solomon E. Morris JR, et al. Among authors: pangon l. Nature. 2009 Dec 17;462(7275):886-90. doi: 10.1038/nature08593. Nature. 2009. PMID: 20016594

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Neuropeptide Y1 receptor in immune cells regulates inflammation and insulin resistance associated with diet-induced obesity.

Macia L, Yulyaningsih E, Pangon L, Nguyen AD, Lin S, Shi YC, Zhang L, Bijker M, Grey S, Mackay F, Herzog H, Sainsbury A. Macia L, et al. Among authors: pangon l. Diabetes. 2012 Dec;61(12):3228-38. doi: 10.2337/db12-0156. Epub 2012 Sep 25. Diabetes. 2012. PMID: 23011592 Free PMC article.

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The PDZ-binding motif of MCC is phosphorylated at position -1 and controls lamellipodia formation in colon epithelial cells.

Pangon L, Van Kralingen C, Abas M, Daly RJ, Musgrove EA, Kohonen-Corish MR. Pangon L, et al. Biochim Biophys Acta. 2012 Jun;1823(6):1058-67. doi: 10.1016/j.bbamcr.2012.03.011. Epub 2012 Mar 28. Biochim Biophys Acta. 2012. PMID: 22480440 Free article.

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Loss of special AT-rich sequence-binding protein 1 (SATB1) predicts poor survival in patients with colorectal cancer.

Al-Sohaily S, Henderson C, Selinger C, Pangon L, Segelov E, Kohonen-Corish MR, Warusavitarne J. Al-Sohaily S, et al. Among authors: pangon l. Histopathology. 2014 Aug;65(2):155-63. doi: 10.1111/his.12295. Epub 2014 May 12. Histopathology. 2014. PMID: 24118100

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The "Mutated in Colorectal Cancer" Protein Is a Novel Target of the UV-Induced DNA Damage Checkpoint.

Pangon L, Sigglekow ND, Larance M, Al-Sohaily S, Mladenova DN, Selinger CI, Musgrove EA, Kohonen-Corish MR. Pangon L, et al. Genes Cancer. 2010 Sep;1(9):917-26. doi: 10.1177/1947601910388937. Genes Cancer. 2010. PMID: 21779472 Free PMC article.

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