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HCN Channels: New Therapeutic Targets for Pain Treatment.

Ramírez D, Zúñiga R, Concha G, Zúñiga L. Ramírez D, et al. Among authors: zuniga l. Molecules. 2018 Aug 21;23(9):2094. doi: 10.3390/molecules23092094. Molecules. 2018. PMID: 30134541 Free PMC article. Review.

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K₂p channels in plants and animals.

González W, Valdebenito B, Caballero J, Riadi G, Riedelsberger J, Martínez G, Ramírez D, Zúñiga L, Sepúlveda FV, Dreyer I, Janta M, Becker D. González W, et al. Among authors: zuniga l. Pflugers Arch. 2015 May;467(5):1091-104. doi: 10.1007/s00424-014-1638-4. Epub 2014 Nov 6. Pflugers Arch. 2015. PMID: 25369776 Review.

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Understanding the Cap Structure in K2P Channels.

Zúñiga L, Zúñiga R. Zúñiga L, et al. Front Physiol. 2016 Jun 14;7:228. doi: 10.3389/fphys.2016.00228. eCollection 2016. Front Physiol. 2016. PMID: 27378938 Free PMC article. No abstract available.

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Elucidating the Structural Basis of the Intracellular pH Sensing Mechanism of TASK-2 K₂P Channels.

Bustos D, Bedoya M, Ramírez D, Concha G, Zúñiga L, Decher N, Hernández-Rodríguez EW, Sepúlveda FV, Martínez L, González W. Bustos D, et al. Among authors: zuniga l. Int J Mol Sci. 2020 Jan 14;21(2):532. doi: 10.3390/ijms21020532. Int J Mol Sci. 2020. PMID: 31947679 Free PMC article.

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Discovery of Novel TASK-3 Channel Blockers Using a Pharmacophore-Based Virtual Screening.

Ramírez D, Concha G, Arévalo B, Prent-Peñaloza L, Zúñiga L, Kiper AK, Rinné S, Reyes-Parada M, Decher N, González W, Caballero J. Ramírez D, et al. Among authors: zuniga l. Int J Mol Sci. 2019 Aug 17;20(16):4014. doi: 10.3390/ijms20164014. Int J Mol Sci. 2019. PMID: 31426491 Free PMC article.

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Withaferin A suppresses breast cancer cell proliferation by inhibition of the two-pore domain potassium (K2P9) channel TASK-3.

Zúñiga R, Concha G, Cayo A, Cikutović-Molina R, Arevalo B, González W, Catalán MA, Zúñiga L. Zúñiga R, et al. Among authors: zuniga l. Biomed Pharmacother. 2020 Sep;129:110383. doi: 10.1016/j.biopha.2020.110383. Epub 2020 Jun 17. Biomed Pharmacother. 2020. PMID: 32563149 Free article.

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TASK-3 Downregulation Triggers Cellular Senescence and Growth Inhibition in Breast Cancer Cell Lines.

Zúñiga R, Valenzuela C, Concha G, Brown N, Zúñiga L. Zúñiga R, et al. Among authors: zuniga l. Int J Mol Sci. 2018 Mar 29;19(4):1033. doi: 10.3390/ijms19041033. Int J Mol Sci. 2018. PMID: 29596383 Free PMC article.

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The Insensitivity of TASK-3 K₂P Channels to External Tetraethylammonium (TEA) Partially Depends on the Cap Structure.

Concha G, Bustos D, Zúñiga R, Catalán MA, Zúñiga L. Concha G, et al. Among authors: zuniga l. Int J Mol Sci. 2018 Aug 18;19(8):2437. doi: 10.3390/ijms19082437. Int J Mol Sci. 2018. PMID: 30126179 Free PMC article.

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Expression and cellular localization of HCN channels in rat cerebellar granule neurons.

Zúñiga R, González D, Valenzuela C, Brown N, Zúñiga L. Zúñiga R, et al. Among authors: zuniga l. Biochem Biophys Res Commun. 2016 Sep 23;478(3):1429-35. doi: 10.1016/j.bbrc.2016.08.141. Epub 2016 Aug 25. Biochem Biophys Res Commun. 2016. PMID: 27569278

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Cardiovascular Action of Insulin in Health and Disease: Endothelial L-Arginine Transport and Cardiac Voltage-Dependent Potassium Channels.

Dubó S, Gallegos D, Cabrera L, Sobrevia L, Zúñiga L, González M. Dubó S, et al. Among authors: zuniga l. Front Physiol. 2016 Mar 15;7:74. doi: 10.3389/fphys.2016.00074. eCollection 2016. Front Physiol. 2016. PMID: 27014078 Free PMC article. Review.

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