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2020 1
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Page 1
Integrated evolutionary analysis reveals antimicrobial peptides with limited resistance.
Spohn R, Daruka L, Lázár V, Martins A, Vidovics F, Grézal G, Méhi O, Kintses B, Számel M, Jangir PK, Csörgő B, Györkei Á, Bódi Z, Faragó A, Bodai L, Földesi I, Kata D, Maróti G, Pap B, Wirth R, Papp B, Pál C. Spohn R, et al. Among authors: daruka l. Nat Commun. 2019 Oct 4;10(1):4538. doi: 10.1038/s41467-019-12364-6. Nat Commun. 2019. PMID: 31586049 Free PMC article.
Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides.
Lázár V, Martins A, Spohn R, Daruka L, Grézal G, Fekete G, Számel M, Jangir PK, Kintses B, Csörgő B, Nyerges Á, Györkei Á, Kincses A, Dér A, Walter FR, Deli MA, Urbán E, Hegedűs Z, Olajos G, Méhi O, Bálint B, Nagy I, Martinek TA, Papp B, Pál C. Lázár V, et al. Among authors: daruka l. Nat Microbiol. 2018 Jun;3(6):718-731. doi: 10.1038/s41564-018-0164-0. Epub 2018 May 24. Nat Microbiol. 2018. PMID: 29795541 Free PMC article.
Cotranslational protein assembly imposes evolutionary constraints on homomeric proteins.
Natan E, Endoh T, Haim-Vilmovsky L, Flock T, Chalancon G, Hopper JTS, Kintses B, Horvath P, Daruka L, Fekete G, Pál C, Papp B, Oszi E, Magyar Z, Marsh JA, Elcock AH, Babu MM, Robinson CV, Sugimoto N, Teichmann SA. Natan E, et al. Among authors: daruka l. Nat Struct Mol Biol. 2018 Mar;25(3):279-288. doi: 10.1038/s41594-018-0029-5. Epub 2018 Feb 12. Nat Struct Mol Biol. 2018. PMID: 29434345 Free PMC article.
New Metabolic Influencer on Oxytocin Release: The Ghrelin.
Szabó R, Ménesi R, H Molnár A, Szalai Z, Daruka L, Tóth G, Gardi J, Gálfi M, Börzsei D, Kupai K, Juhász A, Radács M, László FA, Varga C, Pósa A. Szabó R, et al. Among authors: daruka l. Molecules. 2019 Feb 18;24(4):735. doi: 10.3390/molecules24040735. Molecules. 2019. PMID: 30781678 Free PMC article.
Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action.
Kintses B, Jangir PK, Fekete G, Számel M, Méhi O, Spohn R, Daruka L, Martins A, Hosseinnia A, Gagarinova A, Kim S, Phanse S, Csörgő B, Györkei Á, Ari E, Lázár V, Nagy I, Babu M, Pál C, Papp B. Kintses B, et al. Among authors: daruka l. Nat Commun. 2019 Dec 16;10(1):5731. doi: 10.1038/s41467-019-13618-z. Nat Commun. 2019. PMID: 31844052 Free PMC article.
Rapid Evolution of Reduced Susceptibility against a Balanced Dual-Targeting Antibiotic through Stepping-Stone Mutations.
Szili P, Draskovits G, Révész T, Bogár F, Balogh D, Martinek T, Daruka L, Spohn R, Vásárhelyi BM, Czikkely M, Kintses B, Grézal G, Ferenc G, Pál C, Nyerges Á. Szili P, et al. Among authors: daruka l. Antimicrob Agents Chemother. 2019 Aug 23;63(9):e00207-19. doi: 10.1128/AAC.00207-19. Print 2019 Sep. Antimicrob Agents Chemother. 2019. PMID: 31235632 Free PMC article.
Dual Action of the PN159/KLAL/MAP Peptide: Increase of Drug Penetration across Caco-2 Intestinal Barrier Model by Modulation of Tight Junctions and Plasma Membrane Permeability.
Bocsik A, Gróf I, Kiss L, Ötvös F, Zsíros O, Daruka L, Fülöp L, Vastag M, Kittel Á, Imre N, Martinek TA, Pál C, Szabó-Révész P, Deli MA. Bocsik A, et al. Among authors: daruka l. Pharmaceutics. 2019 Feb 10;11(2):73. doi: 10.3390/pharmaceutics11020073. Pharmaceutics. 2019. PMID: 30744154 Free PMC article.
Exercise training and calorie restriction influence the metabolic parameters in ovariectomized female rats.
Pósa A, Szabó R, Kupai K, Csonka A, Szalai Z, Veszelka M, Török S, Daruka L, Varga C. Pósa A, et al. Among authors: daruka l. Oxid Med Cell Longev. 2015;2015:787063. doi: 10.1155/2015/787063. Epub 2015 Mar 19. Oxid Med Cell Longev. 2015. PMID: 25874022 Free PMC article.
Rational design of balanced dual-targeting antibiotics with limited resistance.
Nyerges A, Tomašič T, Durcik M, Revesz T, Szili P, Draskovits G, Bogar F, Skok Ž, Zidar N, Ilaš J, Zega A, Kikelj D, Daruka L, Kintses B, Vasarhelyi B, Foldesi I, Kata D, Welin M, Kimbung R, Focht D, Mašič LP, Pal C. Nyerges A, et al. Among authors: daruka l. PLoS Biol. 2020 Oct 5;18(10):e3000819. doi: 10.1371/journal.pbio.3000819. eCollection 2020 Oct. PLoS Biol. 2020. PMID: 33017402 Free article.
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