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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1965 1
1969 1
1976 1
1980 1
1981 1
1985 1
1986 2
1992 1
1993 1
1996 2
1997 3
1998 1
1999 2
2000 5
2001 5
2002 7
2003 6
2004 7
2005 7
2006 9
2007 7
2008 7
2009 9
2010 3
2011 7
2012 8
2013 9
2014 1
2015 5
2016 6
2017 7
2018 11
2019 9
2020 5
2021 6
2022 6
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157 results
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Page 1
Adenovirus vectors in hematopoietic stem cell genome editing.
Li C, Lieber A. Li C, et al. Among authors: lieber a. FEBS Lett. 2019 Dec;593(24):3623-3648. doi: 10.1002/1873-3468.13668. Epub 2019 Nov 20. FEBS Lett. 2019. PMID: 31705806 Free article. Review.
Genome editing of hematopoietic stem cells (HSCs) represents a therapeutic option for a number of hematological genetic diseases, as HSCs have the potential for self-renewal and differentiation into all blood cell lineages. ...We discuss HSC genome engineering for s …
Genome editing of hematopoietic stem cells (HSCs) represents a therapeutic option for a number of hematological genetic diseas …
Enhanced HbF reactivation by multiplex mutagenesis of thalassemic CD34+ cells in vitro and in vivo.
Psatha N, Georgakopoulou A, Li C, Nandakumar V, Georgolopoulos G, Acosta R, Paschoudi K, Nelson J, Chee D, Athanasiadou A, Kouvatsi A, Funnell APW, Lieber A, Yannaki E, Papayannopoulou T. Psatha N, et al. Among authors: lieber a. Blood. 2021 Oct 28;138(17):1540-1553. doi: 10.1182/blood.2020010020. Blood. 2021. PMID: 34086867
To broaden the therapeutic window beyond a single-editing approach, we have explored combinations of cis- and trans-editing targets to enhance HbF reactivation. Multiplex mutagenesis in adult CD34+ cells was well tolerated and did not lead to any detectable defect in the …
To broaden the therapeutic window beyond a single-editing approach, we have explored combinations of cis- and trans-editing targets to enhan …
Desmoglein-2 as a prognostic and biomarker in ovarian cancer.
Kim J, Beidler P, Wang H, Li C, Quassab A, Coles C, Drescher C, Carter D, Lieber A. Kim J, et al. Among authors: lieber a. Cancer Biol Ther. 2020 Dec 1;21(12):1154-1162. doi: 10.1080/15384047.2020.1843323. Epub 2020 Nov 20. Cancer Biol Ther. 2020. PMID: 33218274 Free PMC article.
Greater than 80% of all cancer cases are carcinomas, formed by the malignant transformation of epithelial cells. ...Primary ovarian cancer cells were used to study DSG2 levels as they changed in response to cisplatin treatment. ...
Greater than 80% of all cancer cases are carcinomas, formed by the malignant transformation of epithelial cells. ...Primary ov …
[Anthracycline-induced cardiomyopathy].
Roul G, Cohen C, Lieber A. Roul G, et al. Among authors: lieber a. Presse Med. 2009 Jun;38(6):987-94. doi: 10.1016/j.lpm.2009.02.017. Epub 2009 May 7. Presse Med. 2009. PMID: 19423276 Review. French.
Anthracycline-based antineoplastic therapy is the standard of care for various cancers today and represents a breakthrough in this area. The cardiac toxicity of anthracyclines is well established. ...
Anthracycline-based antineoplastic therapy is the standard of care for various cancers today and represents a breakthrough in this ar …
Safe and Effective In Vivo Targeting and Gene Editing in Hematopoietic Stem Cells: Strategies for Accelerating Development.
Cannon P, Asokan A, Czechowicz A, Hammond P, Kohn DB, Lieber A, Malik P, Marks P, Porteus M, Verhoeyen E, Weissman D, Weissman I, Kiem HP. Cannon P, et al. Among authors: lieber a. Hum Gene Ther. 2021 Jan;32(1-2):31-42. doi: 10.1089/hum.2020.263. Hum Gene Ther. 2021. PMID: 33427035 Free PMC article.
On May 11, 2020, the National Institutes of Health (NIH) and the Bill & Melinda Gates Foundation (Gates Foundation) held an exploratory expert scientific roundtable to inform an NIH-Gates Foundation collaboration on the development of scalable, sustainable, and accessible HIV …
On May 11, 2020, the National Institutes of Health (NIH) and the Bill & Melinda Gates Foundation (Gates Foundation) held an exploratory …
Regulation of stem cell plasticity: mechanisms and relevance to tissue biology and cancer.
Strauss R, Hamerlik P, Lieber A, Bartek J. Strauss R, et al. Among authors: lieber a. Mol Ther. 2012 May;20(5):887-97. doi: 10.1038/mt.2012.2. Epub 2012 Feb 7. Mol Ther. 2012. PMID: 22314288 Free PMC article. Review.
Embryonic stem cells (ESCs) are associated with a high degree of plasticity, which allows them to self-renew and differentiate into every somatic cell. ...Transitions between these cell stages have lately been linked to the reacquisition of stem cell features …
Embryonic stem cells (ESCs) are associated with a high degree of plasticity, which allows them to self-renew and differentiate …
In Vivo Hematopoietic Stem Cell Transduction.
Richter M, Stone D, Miao C, Humbert O, Kiem HP, Papayannopoulou T, Lieber A. Richter M, et al. Among authors: lieber a. Hematol Oncol Clin North Am. 2017 Oct;31(5):771-785. doi: 10.1016/j.hoc.2017.06.001. Hematol Oncol Clin North Am. 2017. PMID: 28895846 Free PMC article. Review.
Current protocols for hematopoietic stem cell (HSC) gene therapy, involving the transplantation of ex vivo lentivirus vector-transduced HSCs into myeloablated recipients, are complex and not without risk for the patient. ...
Current protocols for hematopoietic stem cell (HSC) gene therapy, involving the transplantation of ex vivo lentivirus vector-transduc …
Disassembling a cancer puzzle: Cell junctions and plasma membrane as targets for anticancer therapy.
Shilova ON, Shilov ES, Lieber A, Deyev SM. Shilova ON, et al. Among authors: lieber a. J Control Release. 2018 Sep 28;286:125-136. doi: 10.1016/j.jconrel.2018.07.030. Epub 2018 Jul 17. J Control Release. 2018. PMID: 30030181 Review.
We also observe the application of pore forming proteins and peptides of different origin for cytoplasmic delivery of anti-cancer agents and consider the main obstacles of their use in vivo....
We also observe the application of pore forming proteins and peptides of different origin for cytoplasmic delivery of anti-cancer age …
Protein engineering to target complement evasion in cancer.
Carter D, Lieber A. Carter D, et al. Among authors: lieber a. FEBS Lett. 2014 Jan 21;588(2):334-40. doi: 10.1016/j.febslet.2013.11.007. Epub 2013 Nov 14. FEBS Lett. 2014. PMID: 24239543 Free PMC article. Review.
The complement system is composed of soluble factors in plasma that enhance or "complement" immune-mediated killing through innate and adaptive mechanisms. Activation of complement causes recruitment of immune cells; opsonization of coated cells; and direct killing …
The complement system is composed of soluble factors in plasma that enhance or "complement" immune-mediated killing through innate and adapt …
The Long Road to Farewell: The Needs of Families With Dying Children.
Cacciatore J, Thieleman K, Lieber AS, Blood C, Goldman R. Cacciatore J, et al. Among authors: lieber as. Omega (Westport). 2019 Mar;78(4):404-420. doi: 10.1177/0030222817697418. Epub 2017 Mar 8. Omega (Westport). 2019. PMID: 29284313
Families of dying children are profoundly impacted by numerous interactions with health-care providers before, during, and after their child's death. However, there is a dearth of research on these families' direct, qualitative experiences with health-care providers. This …
Families of dying children are profoundly impacted by numerous interactions with health-care providers before, during, and after their child …
157 results