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Systemic administration of an antagomir designed to inhibit miR-92, a regulator of angiogenesis, failed to modulate skeletal anabolic response to mechanical loading.
Sengul A, Santisuk R, Xing W, Kesavan C. Sengul A, et al. Physiol Res. 2013;62(2):221-6. doi: 10.33549/physiolres.932410. Epub 2012 Dec 13. Physiol Res. 2013. PMID: 23234410 Free article.
Administration of miR-92 antagomir was effective in reducing levels of mir-92 in heart, liver and skeletal muscle and in contrast, expression levels of two other microRNA's miR-93 and miR-20a remain constant, thus suggesting specificity of the antagomir used. ...
Administration of miR-92 antagomir was effective in reducing levels of mir-92 in heart, liver and skeletal muscle and in contrast, expressio …
Polymorphism in oestrogen response element associated with variation in plasma angiotensinogen concentrations in healthy pregnant women.
Morgan L, Crawshaw S, Baker PN, Broughton Pipkin F, Kalsheker N. Morgan L, et al. J Hypertens. 2000 May;18(5):553-7. doi: 10.1097/00004872-200018050-00007. J Hypertens. 2000. PMID: 10826557
RESULTS: Women homozygous for the -20C allele had the lowest mean plasma angiotensinogen concentration of 1.7 +/- 0.3micromol/l. Women homozygous for -20A had significantly higher plasma angiotensinogen concentrations (2.6 +/- 0.1 micromol/l), and intermediate levels (2.0 …
RESULTS: Women homozygous for the -20C allele had the lowest mean plasma angiotensinogen concentration of 1.7 +/- 0.3micromol/l. Women homoz …