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1991 1
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31 results

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Page 1
Lipo-Dipeptide as an Emulsifier: Performance and Possible Mechanism.
Lv W, Hu T, Taha A, Wang Z, Xu X, Pan S, Hu H. Lv W, et al. J Agric Food Chem. 2019 Jun 5;67(22):6377-6386. doi: 10.1021/acs.jafc.9b01721. Epub 2019 May 28. J Agric Food Chem. 2019. PMID: 31117499
A lipo-dipeptide (C(13)-lysine-arginine, C(13)-KR) was designed as a potential emulsifier with good emulsifying properties under acidic condition. ...The interfacial tension of C(13)-KR emulsifier was only 3.6 mN/m (0.5% w/v). In conclusion, the lipo-dipeptide C(13) …
A lipo-dipeptide (C(13)-lysine-arginine, C(13)-KR) was designed as a potential emulsifier with good emulsifying properties under acid …
Ginsenoside Rh2-Based Multifunctional Liposomes for Advanced Breast Cancer Therapy.
Hong C, Wang A, Xia J, Liang J, Zhu Y, Wang D, Zhan H, Feng C, Jiang X, Pan J, Wang J. Hong C, et al. Int J Nanomedicine. 2024 Mar 20;19:2879-2888. doi: 10.2147/IJN.S437733. eCollection 2024. Int J Nanomedicine. 2024. PMID: 38525007 Free PMC article.
In the present studies, we established a more realistic large tumor model to test the antitumor activity of a multifunctional ginsenoside Rh2-based liposome system (Rh2-lipo) on advanced breast cancer. METHODS: Both cholesterol and PEG were substituted by Rh2 to prepare th …
In the present studies, we established a more realistic large tumor model to test the antitumor activity of a multifunctional ginsenoside Rh …
Boarding Oncolytic Viruses onto Tumor-Homing Bacterium-Vessels for Augmented Cancer Immunotherapy.
Sun M, Yang S, Huang H, Gao P, Pan S, Cheng Z, He Z, Wang Z, Sun J, Liu F. Sun M, et al. Nano Lett. 2022 Jun 22;22(12):5055-5064. doi: 10.1021/acs.nanolett.2c00699. Epub 2022 May 18. Nano Lett. 2022. PMID: 35583490
Herein, we proposed the concept of bacteria-assisted targeting of OVs to tumors, with liposome-cloaked oncolytic adenoviruses (OAs) conjugated onto tumor-homing Escherichia coli BL21 (designated as E. coli-lipo-OAs) for enhanced cancer immunotherapy. Notably, the enrichmen …
Herein, we proposed the concept of bacteria-assisted targeting of OVs to tumors, with liposome-cloaked oncolytic adenoviruses (OAs) conjugat …
Nitric Oxide-Loaded Bioinspired Lipoprotein Normalizes Tumor Vessels To Improve Intratumor Delivery and Chemotherapy of Albumin-Bound Paclitaxel Nanoparticles.
Wu Y, Xie H, Li Y, Bao X, Lu GL, Wen J, Gao Y, Li Y, Zhang Z. Wu Y, et al. Nano Lett. 2023 Feb 8;23(3):939-947. doi: 10.1021/acs.nanolett.2c04312. Epub 2023 Jan 26. Nano Lett. 2023. PMID: 36701555
Herein, we rationally designed a glutathione (GSH)-activated nitric oxide (NO) donor loaded bioinspired lipoprotein system (NO-BLP) to normalize tumor vessels and then promote the delivery efficiency of sequential albumin-bound paclitaxel nanoparticles (PAN) in tumors. NO- …
Herein, we rationally designed a glutathione (GSH)-activated nitric oxide (NO) donor loaded bioinspired lipoprotein system (NO-BLP) to norma …
Liposomal Dendritic Cell Vaccine in Breast Cancer Immunotherapy.
Pan H, Shi H, Fu P, Shi P, Yang J. Pan H, et al. ACS Omega. 2021 Jan 25;6(5):3991-3998. doi: 10.1021/acsomega.0c05924. eCollection 2021 Feb 9. ACS Omega. 2021. PMID: 33585776 Free PMC article.
Herein, a folic acid (FA)-modified liposome was constructed and loaded with chlorin e6 (Ce6) as a DC vaccine (FA-Lipo-Ce6). It was suggested that the loaded Ce6 within FA-Lipo-Ce6 can be activated under laser irradiation. ...Most importantly, the employment of DC ca …
Herein, a folic acid (FA)-modified liposome was constructed and loaded with chlorin e6 (Ce6) as a DC vaccine (FA-Lipo-Ce6). It was su …
EGFR-Targeted Liposomes Combined with Ginsenoside Rh2 Inhibit Triple-Negative Breast Cancer Growth and Metastasis.
Gu H, Shi R, Xu C, Lv W, Hu X, Xu C, Pan Y, He X, Wu A, Li J. Gu H, et al. Bioconjug Chem. 2023 Jun 21;34(6):1157-1165. doi: 10.1021/acs.bioconjchem.3c00207. Epub 2023 May 26. Bioconjug Chem. 2023. PMID: 37235785
In comparison to non-targeted liposomes (Rh2@Lipo and LTL@Rh2@Lipo), the nanoliposomes LTL@Rh2@Lipo-GE11 demonstrated a high specificity to MDA-MB-231 cells that expressed a high level of EGFR both in vitro and in vivo, contributing to the strong inhibitory e …
In comparison to non-targeted liposomes (Rh2@Lipo and LTL@Rh2@Lipo), the nanoliposomes LTL@Rh2@Lipo-GE11 demonstrated a …
Enhanced antitumor and anti-metastasis by VEGFR2-targeted doxorubicin immunoliposome synergy with NK cell activation.
Pan M, Liu Y, Sang T, Xie J, Lin H, Wei J, Shao S, Zheng Y, Zhang J. Pan M, et al. Invest New Drugs. 2023 Oct;41(5):664-676. doi: 10.1007/s10637-023-01372-5. Epub 2023 Aug 5. Invest New Drugs. 2023. PMID: 37542666
To enhance antitumor efficacy of PEGylated liposomal doxorubicin, we constructed a VEGFR2-targeted and doxorubicin-loaded immunoliposome (Lipo-DOX-C00) by conjugating a VEGFR2-specific, single chain antibody fragment to DSPE-PEG2000-MAL, and then we inserted the antibody-c …
To enhance antitumor efficacy of PEGylated liposomal doxorubicin, we constructed a VEGFR2-targeted and doxorubicin-loaded immunoliposome ( …
Macrophage contribution to the survival of transferred expanded skin flap through angiogenesis.
Huang Z, Ding J, Song Y, Liu W, Dong C, Zhang Y, Wang T, Du J, Xiong S, He Q, Yu Z, Ma X. Huang Z, et al. Ann Transl Med. 2023 Mar 31;11(6):248. doi: 10.21037/atm-22-1558. Epub 2023 Jan 30. Ann Transl Med. 2023. PMID: 37082668 Free PMC article.
RESULTS: The number of pan-macrophages significantly increased in the expanded scalp on days 14 and 21 after expander placement. The depletion rate after treatment with Clo-lipo was 29.06%, and the number of macrophages was significantly reduced in the group that un …
RESULTS: The number of pan-macrophages significantly increased in the expanded scalp on days 14 and 21 after expander placement. The …
An effective dual-factor modified 3D-printed PCL scaffold for bone defect repair.
Li Y, Li Q, Li H, Xu X, Fu X, Pan J, Wang H, Fuh JYH, Bai Y, Wei S. Li Y, et al. J Biomed Mater Res B Appl Biomater. 2020 Jul;108(5):2167-2179. doi: 10.1002/jbm.b.34555. Epub 2020 Jan 6. J Biomed Mater Res B Appl Biomater. 2020. PMID: 31904173
We consider that appropriate, simultaneous application of two types of bioactive molecules would accelerate the regeneration of tissues and organs. Therefore, we combined aspirin-loaded liposomes (Asp@Lipo) and bone forming peptide-1 (BFP-1) on three dimensional-printed po …
We consider that appropriate, simultaneous application of two types of bioactive molecules would accelerate the regeneration of tissues and …
An ATF24 peptide-functionalized β-elemene-nanostructured lipid carrier combined with cisplatin for bladder cancer treatment.
Zhai B, Chen P, Wang W, Liu S, Feng J, Duan T, Xiang Y, Zhang R, Zhang M, Han X, Chen X, Li Q, Li G, Liu Y, Huang X, Zhang W, Pan T, Yan L, Jin T, Xie T, Sui X. Zhai B, et al. Cancer Biol Med. 2020 Aug 15;17(3):676-692. doi: 10.20892/j.issn.2095-3941.2020.0454. Cancer Biol Med. 2020. PMID: 32944399 Free PMC article.
ATF(24)-PEG-Lipo-beta-E had better targeting efficiency and higher cytotoxicity than polyethylene glycol (PEG)ylated beta-elemene liposomes (PEG-Lipo-beta-E). DDP, combined with ATF(24)-PEG-Lipo-beta-E, exerted a synergistic effect on cellular apoptosis and c …
ATF(24)-PEG-Lipo-beta-E had better targeting efficiency and higher cytotoxicity than polyethylene glycol (PEG)ylated beta-elemene lip …
31 results