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Year Number of Results
2002 1
2003 2
2004 1
2005 1
2006 2
2007 1
2010 1
2011 2
2012 2
2013 1
2015 1
2018 1
2019 1
2021 1
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Page 1
Coupled Enzyme Activity and Thermal Shift Screening of the Maybridge Rule of 3 Fragment Library Against Trypanosoma brucei Choline Kinase; A Genetically Validated Drug Target.
Major LL, Denton H, Smith TK. Major LL, et al. In: El-Shemy HA, editor. Drug Discovery [Internet]. Rijeka (HR): InTech; 2013 Jan 23. Chapter 14. In: El-Shemy HA, editor. Drug Discovery [Internet]. Rijeka (HR): InTech; 2013 Jan 23. Chapter 14. PMID: 28045479 Free Books & Documents. Review.
Inhibitors of Trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease.
Gaspar L, Coron RP, KongThoo Lin P, Costa DM, Perez-Cabezas B, Tavares J, Roura-Ferrer M, Ramos I, Ronin C, Major LL, Ciesielski F, Pemberton IK, MacDougall J, Ciapetti P, Smith TK, Cordeiro-da-Silva A. Gaspar L, et al. Among authors: major ll. PLoS Negl Trop Dis. 2018 Jan 22;12(1):e0006180. doi: 10.1371/journal.pntd.0006180. eCollection 2018 Jan. PLoS Negl Trop Dis. 2018. PMID: 29357372 Free PMC article.
Tandem termination signals: myth or reality?
Major LL, Edgar TD, Yee Yip P, Isaksson LA, Tate WP. Major LL, et al. FEBS Lett. 2002 Mar 6;514(1):84-9. doi: 10.1016/s0014-5793(02)02301-3. FEBS Lett. 2002. PMID: 11904187 Free article.
Toward Chemical Validation of Leishmania infantum Ribose 5-Phosphate Isomerase as a Drug Target.
Dickie EA, Ronin C, Sá M, Ciesielski F, Trouche N, Tavares J, Santarem N, Major LL, Pemberton IK, MacDougall J, Smith TK, Cordeiro-da-Silva A, Ciapetti P. Dickie EA, et al. Among authors: major ll. Antimicrob Agents Chemother. 2021 Jun 17;65(7):e0189220. doi: 10.1128/AAC.01892-20. Epub 2021 Jun 17. Antimicrob Agents Chemother. 2021. PMID: 33875438
Synthesis and biological evaluation of CTP synthetase inhibitors as potential agents for the treatment of African trypanosomiasis.
Tamborini L, Pinto A, Smith TK, Major LL, Iannuzzi MC, Cosconati S, Marinelli L, Novellino E, Lo Presti L, Wong PE, Barrett MP, De Micheli C, Conti P. Tamborini L, et al. Among authors: major ll. ChemMedChem. 2012 Sep;7(9):1623-34. doi: 10.1002/cmdc.201200304. Epub 2012 Aug 2. ChemMedChem. 2012. PMID: 22865834 Free PMC article.
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