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Neutrophils promote clearance of nuclear debris following acid-induced lung injury.

Oved JH, Paris AJ, Gollomp K, Dai N, Rubey K, Wang P, Spruce LA, Seeholzer SH, Poncz M, Worthen GS. Oved JH, et al. Among authors: spruce la. Blood. 2021 Jan 21;137(3):392-397. doi: 10.1182/blood.2020005505. Blood. 2021. PMID: 32959045 Free PMC article.

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Improved surfaceome coverage with a label-free nonaffinity-purified workflow.

Glisovic-Aplenc T, Gill S, Spruce LA, Smith IR, Fazelinia H, Shestova O, Ding H, Tasian SK, Aplenc R, Seeholzer SH. Glisovic-Aplenc T, et al. Among authors: spruce la. Proteomics. 2017 Apr;17(7):10.1002/pmic.201600344. doi: 10.1002/pmic.201600344. Epub 2017 Mar 6. Proteomics. 2017. PMID: 28116781 Free PMC article.

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Stability and bioactivity of pepCD47 attachment on stainless steel surfaces.

Inamdar VV, Fitzpatrick E, Alferiev I, Nagaswami C, Spruce LA, Fazelinia H, Bratinov G, Seeholzer SH, Levy RJ, Fishbein I, Stachelek SJ. Inamdar VV, et al. Among authors: spruce la. Acta Biomater. 2020 Mar 1;104:231-240. doi: 10.1016/j.actbio.2019.12.039. Epub 2020 Jan 11. Acta Biomater. 2020. PMID: 31935523 Free PMC article.

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Plasma Nucleosomes Are Associated With Mortality in Pediatric Acute Respiratory Distress Syndrome.

Yehya N, Fazelinia H, Lawrence GG, Spruce LA, Mai MV, Worthen GS, Christie JD. Yehya N, et al. Among authors: spruce la. Crit Care Med. 2021 Jul 1;49(7):1149-1158. doi: 10.1097/CCM.0000000000004923. Crit Care Med. 2021. PMID: 33729723

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Mitochondrial morphology, bioenergetics and proteomic responses in fatty acid oxidation disorders.

Raimo S, Zura-Miller G, Fezelinia H, Spruce LA, Zakopoulos I, Mohsen AW, Vockley J, Ischiropoulos H. Raimo S, et al. Among authors: spruce la. Redox Biol. 2021 May;41:101923. doi: 10.1016/j.redox.2021.101923. Epub 2021 Mar 2. Redox Biol. 2021. PMID: 33725513 Free PMC article.

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Regulation of Janus Kinase 2 by an Inflammatory Bowel Disease Causal Non-coding Single Nucleotide Polymorphism.

Cardinale CJ, March ME, Lin X, Liu Y, Spruce LA, Bradfield JP, Wei Z, Seeholzer SH, Grant SFA, Hakonarson H. Cardinale CJ, et al. Among authors: spruce la. J Crohns Colitis. 2020 Jun 19;14(5):646-653. doi: 10.1093/ecco-jcc/jjz213. J Crohns Colitis. 2020. PMID: 32271392

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The E3 ubiquitin ligase Itch restricts antigen-driven B cell responses.

Moser EK, Roof J, Dybas JM, Spruce LA, Seeholzer SH, Cancro MP, Oliver PM. Moser EK, et al. Among authors: spruce la. J Exp Med. 2019 Sep 2;216(9):2170-2183. doi: 10.1084/jem.20181953. Epub 2019 Jul 16. J Exp Med. 2019. PMID: 31311822 Free PMC article.

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ER-luminal [Ca²⁺] regulation of InsP₃ receptor gating mediated by an ER-luminal peripheral Ca²⁺-binding protein.

Vais H, Wang M, Mallilankaraman K, Payne R, McKennan C, Lock JT, Spruce LA, Fiest C, Chan MY, Parker I, Seeholzer SH, Foskett JK, Mak DD. Vais H, et al. Among authors: spruce la. Elife. 2020 May 18;9:e53531. doi: 10.7554/eLife.53531. Elife. 2020. PMID: 32420875 Free PMC article.

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The E3 ubiquitin ligase Cul4b promotes CD4+ T cell expansion by aiding the repair of damaged DNA.

Dar AA, Sawada K, Dybas JM, Moser EK, Lewis EL, Park E, Fazelinia H, Spruce LA, Ding H, Seeholzer SH, Oliver PM. Dar AA, et al. Among authors: spruce la. PLoS Biol. 2021 Feb 1;19(2):e3001041. doi: 10.1371/journal.pbio.3001041. eCollection 2021 Feb. PLoS Biol. 2021. PMID: 33524014 Free PMC article.

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The Neuroprotective Marine Compound Psammaplysene A Binds the RNA-Binding Protein HNRNPK.

Boccitto M, Lee N, Sakamoto S, Spruce LA, Handa H, Clardy J, Seeholzer SH, Kalb RG. Boccitto M, et al. Among authors: spruce la. Mar Drugs. 2017 Aug 7;15(8):246. doi: 10.3390/md15080246. Mar Drugs. 2017. PMID: 28783126 Free PMC article.

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