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Page 1
Dynamic IgG antibody response to immunodominant antigens of M. tuberculosis for active TB diagnosis in high endemic settings.
Pathakumari B, Prabhavathi M, Anbarasu D, Paramanandhan P, Raja A. Pathakumari B, et al. Clin Chim Acta. 2016 Oct 1;461:25-33. doi: 10.1016/j.cca.2016.06.033. Epub 2016 Jun 28. Clin Chim Acta. 2016. PMID: 27370403
Hence, one of the possibilities is identification of Mycobacterium tuberculosis specific antibodies in infected serum by using specific antigens. METHODS: We tested 10 recombinant M. tuberculosis antigens to evaluate IgG levels among Healthy control subjects (HCS), Healthy …
Hence, one of the possibilities is identification of Mycobacterium tuberculosis specific antibodies in infected serum by using specific anti …
Crystal structure of 2-amino-5-nitro-pyridinium sulfamate.
Rajkumar MA, NizamMohideen M, Xavier SS, Anbarasu S, Devarajan DP. Rajkumar MA, et al. Acta Crystallogr E Crystallogr Commun. 2015 Jan 31;71(Pt 2):231-3. doi: 10.1107/S2056989015000365. eCollection 2015 Feb 1. Acta Crystallogr E Crystallogr Commun. 2015. PMID: 25878827 Free PMC article.
As expected, this protonation leads to the widening of the C-N-C angle of the pyridine ring, to 122.9 (3), with the pyridinium ring being essentially planar (r.m.s. deviation = 0.025 A). In the crystal, the ion pairs are joined by three N-HO and one N-HN hydrogen bonds in …
As expected, this protonation leads to the widening of the C-N-C angle of the pyridine ring, to 122.9 (3), with the pyridinium ring being es …
Designing multi-epitope vaccine against human cytomegalovirus integrating pan-genome and reverse vaccinology pipelines.
Biswas R, Swetha RG, Basu S, Roy A, Ramaiah S, Anbarasu A. Biswas R, et al. Biologicals. 2024 Aug;87:101782. doi: 10.1016/j.biologicals.2024.101782. Epub 2024 Jul 13. Biologicals. 2024. PMID: 39003966
In this study, we employed a pan-genome and reverse vaccinology approach to screen the target for efficient vaccine candidates. Four proteins, envelope glycoprotein M, UL41A, US23, and US28, were shortlisted based on cellular localization, high solubility, antigenicity, an …
In this study, we employed a pan-genome and reverse vaccinology approach to screen the target for efficient vaccine candidates. Four protein …
Essentiality Assessment of Cysteinyl and Lysyl-tRNA Synthetases of Mycobacterium smegmatis.
Ravishankar S, Ambady A, Swetha RG, Anbarasu A, Ramaiah S, Sambandamurthy VK. Ravishankar S, et al. PLoS One. 2016 Jan 21;11(1):e0147188. doi: 10.1371/journal.pone.0147188. eCollection 2016. PLoS One. 2016. PMID: 26794499 Free PMC article.
Herein, we describe sequence and structural analysis of the additional aminoacyl-tRNA synthetase genes found in M. smegmatis. Characterization of conditional expression strains of Cysteinyl and Lysyl-tRNA synthetases generated in M. smegmatis revealed that the canon …
Herein, we describe sequence and structural analysis of the additional aminoacyl-tRNA synthetase genes found in M. smegmatis. Charact …
Transcriptional expression of secondary resistance genes ccdB and repA2 is enhanced in presence of cephalosporin and carbapenem in Escherichia coli.
Baishya S, Deshamukhya C, Wangkheimayum J, Das BJ, Anbarasu A, Talukdar AD, Bhattacharjee A, Choudhury MD. Baishya S, et al. BMC Microbiol. 2021 Mar 9;21(1):79. doi: 10.1186/s12866-021-02136-y. BMC Microbiol. 2021. PMID: 33750290 Free PMC article.
In this context influential genes belonging to secondary resistome that act as helper to the primary resistance genes like bla(NDM) and bla(CTX-M) in aggravating beta-lactam resistance were selected from an earlier reported in silico study. ...CONCLUSION: SRGs repA2 and cc …
In this context influential genes belonging to secondary resistome that act as helper to the primary resistance genes like bla(NDM) and bla( …
Genome sequencing and molecular characterisation of XDR Acinetobacter baumannii reveal complexities in resistance: Novel combination of sulbactam-durlobactam holds promise for therapeutic intervention.
Naha A, Vijayakumar S, Lal B, Shankar BA, Chandran S, Ramaiah S, Veeraraghavan B, Anbarasu A. Naha A, et al. J Cell Biochem. 2021 Dec;122(12):1946-1957. doi: 10.1002/jcb.30156. Epub 2021 Oct 1. J Cell Biochem. 2021. PMID: 34597421
Furthermore, higher binding affinities and low inhibition constants were noted in OXA23-DUR (-7.36 kcal/mol; 4.01 M), OXA58-DUR (-6.44 kcal/mol; 19.07 M), and NDM-DUR (-6.82 kcal/mol; 10.01 M) complexes when compared with the conventional drugs avibactam and …
Furthermore, higher binding affinities and low inhibition constants were noted in OXA23-DUR (-7.36 kcal/mol; 4.01 M), OXA58-DUR (-6.4 …
Isolation of Potential Compound from the Leaves of Elytraria acaulis and Evaluating Its Therapeutic Properties Using In Vitro Studies Against Ovarian Cancer.
Priya P, Anbarasu M, Christina VS, Majeed SA, Sivamurugan V, Sundaram RL. Priya P, et al. Appl Biochem Biotechnol. 2022 Dec;194(12):5607-5626. doi: 10.1007/s12010-022-04048-7. Epub 2022 Jul 7. Appl Biochem Biotechnol. 2022. PMID: 35796948
In the cell cycle analysis, the isolated compound induced a significant increase in the percentage of cells in G0/G1 phase and a decrease in the percentage of cells in the S phase and G2-M phase of the PA 1 cell lines. The cell cycle arrest induced by the isolated compound …
In the cell cycle analysis, the isolated compound induced a significant increase in the percentage of cells in G0/G1 phase and a decrease in …
23 results