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Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.
Marso SP, Bain SC, Consoli A, Eliaschewitz FG, Jódar E, Leiter LA, Lingvay I, Rosenstock J, Seufert J, Warren ML, Woo V, Hansen O, Holst AG, Pettersson J, Vilsbøll T; SUSTAIN-6 Investigators. Marso SP, et al. N Engl J Med. 2016 Nov 10;375(19):1834-1844. doi: 10.1056/NEJMoa1607141. Epub 2016 Sep 15. N Engl J Med. 2016. PMID: 27633186 Free article. Clinical Trial.
Global injury morbidity and mortality from 1990 to 2017: results from the Global Burden of Disease Study 2017.
James SL, Castle CD, Dingels ZV, Fox JT, Hamilton EB, Liu Z, S Roberts NL, Sylte DO, Henry NJ, LeGrand KE, Abdelalim A, Abdoli A, Abdollahpour I, Abdulkader RS, Abedi A, Abosetugn AE, Abushouk AI, Adebayo OM, Agudelo-Botero M, Ahmad T, Ahmed R, Ahmed MB, Eddine Aichour MT, Alahdab F, Alamene GM, Alanezi FM, Alebel A, Alema NM, Alghnam SA, Al-Hajj S, Ali BA, Ali S, Alikhani M, Alinia C, Alipour V, Aljunid SM, Almasi-Hashiani A, Almasri NA, Altirkawi K, Abdeldayem Amer YS, Amini S, Loreche Amit AM, Andrei CL, Ansari-Moghaddam A, T Antonio CA, Yaw Appiah SC, Arabloo J, Arab-Zozani M, Arefi Z, Aremu O, Ariani F, Arora A, Asaad M, Asghari B, Awoke N, Ayala Quintanilla BP, Ayano G, Ayanore MA, Azari S, Azarian G, Badawi A, Badiye AD, Bagli E, Baig AA, Bairwa M, Bakhtiari A, Balachandran A, Banach M, Banerjee SK, Banik PC, Banstola A, Barker-Collo SL, Bärnighausen TW, Barrero LH, Barzegar A, Bayati M, Baye BA, Bedi N, Behzadifar M, Bekuma TT, Belete H, Benjet C, Bennett DA, Bensenor IM, Berhe 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Zodpey S, Dandona L, Dandona R, Degenhardt L, Dharmaratne SD, Hay SI, Mokdad AH, Reiner RC Jr, Sartorius B, Vos T. James SL, et al. Inj Prev. 2020 Oct;26(Supp 1):i96-i114. doi: 10.1136/injuryprev-2019-043494. Epub 2020 Apr 24. Inj Prev. 2020. PMID: 32332142 Free PMC article.
Association of Multiple Plasma Biomarker Concentrations with Progression of Prevalent Diabetic Kidney Disease: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study.
Schrauben SJ, Shou H, Zhang X, Anderson AH, Bonventre JV, Chen J, Coca S, Furth SL, Greenberg JH, Gutierrez OM, Ix JH, Lash JP, Parikh CR, Rebholz CM, Sabbisetti V, Sarnak MJ, Shlipak MG, Waikar SS, Kimmel PL, Vasan RS, Feldman HI, Schelling JR; CKD Biomarkers Consortium and the Chronic Renal Insufficiency Cohort (CRIC) Study Investigators. Schrauben SJ, et al. J Am Soc Nephrol. 2021 Jan;32(1):115-126. doi: 10.1681/ASN.2020040487. Epub 2020 Oct 29. J Am Soc Nephrol. 2021. PMID: 33122288
METHODS: In our case-cohort study of 894 Chronic Renal Insufficiency Cohort Study participants with diabetes and an eGFR of <60 ml/min per 1.73 m(2) at baseline, participants were randomly selected for the subcohort; cases were those patients who developed progressive d …
METHODS: In our case-cohort study of 894 Chronic Renal Insufficiency Cohort Study participants with diabetes and an eGFR of <60 ml/min pe …
M/g-C(3)N(4) (M=Ag, Au, and Pd) composite: synthesis via sunlight photodeposition and application towards the degradation of bisphenol A.
Hak CH, Sim LC, Leong KH, Lim PF, Chin YH, Saravanan P. Hak CH, et al. Environ Sci Pollut Res Int. 2018 Sep;25(25):25401-25412. doi: 10.1007/s11356-018-2632-8. Epub 2018 Jun 27. Environ Sci Pollut Res Int. 2018. PMID: 29951757
The improved degradation lies crucially on the particle size and Schottky barrier formation at the interface of M/g-C(3)N(4) (M=Au, Ag, and Pd) but not the visible light harvesting properties. ...
The improved degradation lies crucially on the particle size and Schottky barrier formation at the interface of M/g-C(3)N(4) (M
Development and validation of a new UPLC-MS/MS method for quantification of ganoderic acid-A loaded nanolipidic carrier in rat plasma and application to pharmacokinetic studies.
Rahman M, Almalki WH, Kazmi I, Afzal O, Katouah HA, Alrobaian M, Altamimi ASA, Al-Abbasi FA, Alshammari MS, Rub RA, Beg S, Kumar V. Rahman M, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Jan 15;1163:122501. doi: 10.1016/j.jchromb.2020.122501. Epub 2020 Dec 18. J Chromatogr B Analyt Technol Biomed Life Sci. 2021. PMID: 33388522
Separation of the analyte was achieved using ACQUITY UPLC BEH C(18) column (1.7 m) and mobile phase as water containing 0.1% Acetonitrile (40: 60% v/v) at a flow rate of 0.4 mLmin(-1). The analyte was detected using MRM mode to track precursor-to-product ion transitions of …
Separation of the analyte was achieved using ACQUITY UPLC BEH C(18) column (1.7 m) and mobile phase as water containing 0.1% Acetonit …
Induction of selective cytotoxicity and apoptosis in human T4-lymphoblastoid cell line (CEMss) by boesenbergin a isolated from boesenbergia rotunda rhizomes involves mitochondrial pathway, activation of caspase 3 and G2/M phase cell cycle arrest.
Ng KB, Bustamam A, Sukari MA, Abdelwahab SI, Mohan S, Buckle MJ, Kamalidehghan B, Nadzri NM, Anasamy T, A Hadi AH, Rahman HS. Ng KB, et al. BMC Complement Altern Med. 2013 Feb 22;13:41. doi: 10.1186/1472-6882-13-41. BMC Complement Altern Med. 2013. PMID: 23432947 Free PMC article.
The cell cycle analysis indicated that boesenbergin A was able to induce G2/M phase arrest in CEMss cells. The activity of caspases -3/7, -8 and -9 was increased after treatment which indicates both intrinsic and extrinsic pathways are induced during apoptosis. ...CONCLUSI …
The cell cycle analysis indicated that boesenbergin A was able to induce G2/M phase arrest in CEMss cells. The activity of caspases - …
Design and synthesis of 1,2,4-triazolo[1,5-a]pyrimidine derivatives as PDE 4B inhibitors endowed with bronchodilator activity.
Abd El-Aleam RH, George RF, Lee KJ, Keeton AB, Piazza GA, Kamel AA, El-Daly ME, Hassan GS, Abdel-Rahman HM. Abd El-Aleam RH, et al. Arch Pharm (Weinheim). 2019 Aug;352(8):e1900002. doi: 10.1002/ardp.201900002. Epub 2019 Jul 29. Arch Pharm (Weinheim). 2019. PMID: 31353608
A series of 1,2,4-triazolo[1,5-a]pyrimidine derivatives was designed, synthesized, and screened for their phosphodiesterase (PDE 4B) inhibitory activity and bronchodilation ability. Compound 7e showed 41.80% PDE 4B inhibition at 10 M. Eight compounds were screened for thei …
A series of 1,2,4-triazolo[1,5-a]pyrimidine derivatives was designed, synthesized, and screened for their phosphodiesterase (PDE 4B) inhibit …
Structural studies of Chikungunya virus maturation.
Yap ML, Klose T, Urakami A, Hasan SS, Akahata W, Rossmann MG. Yap ML, et al. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13703-13707. doi: 10.1073/pnas.1713166114. Epub 2017 Dec 4. Proc Natl Acad Sci U S A. 2017. PMID: 29203665 Free PMC article.
Plasma Immunoglobulin A Responses Against 2 Salmonella Typhi Antigens Identify Patients With Typhoid Fever.
Andrews JR, Khanam F, Rahman N, Hossain M, Bogoch II, Vaidya K, Kelly M, Calderwood SB, Bhuiyan TR, Ryan ET, Qadri F, Charles RC. Andrews JR, et al. Clin Infect Dis. 2019 Mar 5;68(6):949-955. doi: 10.1093/cid/ciy578. Clin Infect Dis. 2019. PMID: 30020426 Free PMC article.
METHODS: We assessed plasma antibody responses (immunoglobulin [Ig] M, IgA, and IgG) to these antigens by means of enzyme-linked immunosorbent assay in patients with suspected enteric fever, controls with other febrile illnesses, and healthy controls in Dhaka, Bangladesh a …
METHODS: We assessed plasma antibody responses (immunoglobulin [Ig] M, IgA, and IgG) to these antigens by means of enzyme-linked immu …
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