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Lixisenatide in Patients with Type 2 Diabetes and Acute Coronary Syndrome.
Pfeffer MA, Claggett B, Diaz R, Dickstein K, Gerstein HC, Køber LV, Lawson FC, Ping L, Wei X, Lewis EF, Maggioni AP, McMurray JJ, Probstfield JL, Riddle MC, Solomon SD, Tardif JC; ELIXA Investigators. Pfeffer MA, et al. N Engl J Med. 2015 Dec 3;373(23):2247-57. doi: 10.1056/NEJMoa1509225. N Engl J Med. 2015. PMID: 26630143 Free article. Clinical Trial.
Structure and functional properties of Capto™ Core 700 core-shell particles.
Sánchez-Trasviña C, Fuks P, Mushagasha C, Kimerer L, Mayolo-Deloisa K, Rito-Palomares M, Carta G. Sánchez-Trasviña C, et al. J Chromatogr A. 2020 Jun 21;1621:461079. doi: 10.1016/j.chroma.2020.461079. Epub 2020 Apr 15. J Chromatogr A. 2020. PMID: 32360061
The resin average bead size is 90.7 mum with a range of 50-130 mum, the shell thickness is 4.18 m with a range of 3-6 m and a standard deviation of 0.55 m, and the pore radius, obtained by inverse size exclusion chromatography, is 50.4 1.3 nm. ...
The resin average bead size is 90.7 mum with a range of 50-130 mum, the shell thickness is 4.18 m with a range of 3-6 m and a …
Nitrergic relaxation of the horse corpus cavernosum. Role of cGMP.
Recio P, López PG, Hernández M, Prieto D, Contreras J, García-Sacristán A. Recio P, et al. Eur J Pharmacol. 1998 Jun 12;351(1):85-94. doi: 10.1016/s0014-2999(98)00282-9. Eur J Pharmacol. 1998. PMID: 9698209
Relaxations in response to electrical field stimulation were tetrodotoxin (10(-6) M)-sensitive, indicating their neurogenic origin. The NO synthase inhibitor, L-NO-arginine (L-NO-Arg, 3 x 10(-5) M), abolished the electrically induced relaxations, which were signific …
Relaxations in response to electrical field stimulation were tetrodotoxin (10(-6) M)-sensitive, indicating their neurogenic origin. T …
Endothelin A (ET(A)) receptors are involved in augmented adrenergic vasoconstriction and blunted nitric oxide-mediated relaxation of penile arteries from insulin-resistant obese zucker rats.
Sánchez A, Contreras C, Martínez P, Muñoz M, Martínez AC, García-Sacristán A, Hernández M, Prieto D. Sánchez A, et al. J Sex Med. 2014 Jun;11(6):1463-74. doi: 10.1111/jsm.12526. Epub 2014 Apr 4. J Sex Med. 2014. PMID: 24697908
MAIN OUTCOME MEASURES: Changes in neural nitrergic relaxation and adrenergic vasoconstriction and the expression of ET receptors in perivascular nerves were assessed. RESULTS: ET-1 (10(-10) M) enhanced EFS-induced vasoconstriction, and treatment with the adrenergic neuroto …
MAIN OUTCOME MEASURES: Changes in neural nitrergic relaxation and adrenergic vasoconstriction and the expression of ET receptors in perivasc …
Phase I studies of imatinib mesylate combined with cisplatin and irinotecan in patients with small cell lung carcinoma.
Johnson FM, Krug LM, Tran HT, Shoaf S, Prieto VG, Tamboli P, Peeples B, Patel J, Glisson BS. Johnson FM, et al. Cancer. 2006 Jan 15;106(2):366-74. doi: 10.1002/cncr.21640. Cancer. 2006. PMID: 16342249 Free article. Clinical Trial.
CONCLUSIONS: The maximum tolerated dose for this combination with granulocyte-colony-stimulating factor support was identified as imatinib at a dose of 300 mg/day with irinotecan (at a dose of 65 mg/m(2)) and cisplatin (at a dose of 30 mg/m(2)) given on Days 1 and 8 …
CONCLUSIONS: The maximum tolerated dose for this combination with granulocyte-colony-stimulating factor support was identified as imatinib a …
Growth hormone-releasing hormone (GHRH) promotes metastatic phenotypes through EGFR/HER2 transactivation in prostate cancer cells.
Muñoz-Moreno L, Bajo AM, Prieto JC, Carmena MJ. Muñoz-Moreno L, et al. Mol Cell Endocrinol. 2017 May 5;446:59-69. doi: 10.1016/j.mce.2017.02.011. Epub 2017 Feb 11. Mol Cell Endocrinol. 2017. PMID: 28193499
In addition, we assessed cell cycle, cell migration and VEGF secretion in PC3 cells. GHRH augmented the number of cells in G2/M-phase but diminished that corresponding to G1-phase. Cell-cycle specific markers were evaluated since GHRH effects may be related to their differ …
In addition, we assessed cell cycle, cell migration and VEGF secretion in PC3 cells. GHRH augmented the number of cells in G2/M-phase …
Cytotactin expression in somites after dorsal neural tube and neural crest ablation in chicken embryos.
Tan SS, Prieto AL, Newgreen DF, Crossin KL, Edelman GM. Tan SS, et al. Proc Natl Acad Sci U S A. 1991 Aug 1;88(15):6398-402. doi: 10.1073/pnas.88.15.6398. Proc Natl Acad Sci U S A. 1991. PMID: 1713677 Free PMC article.
We conclude that, contrary to the suggestion of Stern et al. [Stern, C. D., Norris, W. E., Bronner-Fraser, M., Carlson, G. J., Faissner, A., Keynes, R. J. & Schachner, M. (1989) Development 107, 309-319], there is no causal link between the presence of NC cells …
We conclude that, contrary to the suggestion of Stern et al. [Stern, C. D., Norris, W. E., Bronner-Fraser, M., Carlson, G. J., Faissn …
Intramolecular DNA coiling mediated by metallo-supramolecular cylinders: differential binding of P and M helical enantiomers.
Meistermann I, Moreno V, Prieto MJ, Moldrheim E, Sletten E, Khalid S, Rodger PM, Peberdy JC, Isaac CJ, Rodger A, Hannon MJ. Meistermann I, et al. Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5069-74. doi: 10.1073/pnas.062634499. Proc Natl Acad Sci U S A. 2002. PMID: 11959957 Free PMC article.
We have designed a synthetic tetracationic metallo-supramolecular cylinder that targets the major groove of DNA with a binding constant in excess of 10(7) M(-1) and induces DNA bending and intramolecular coiling. The two enantiomers of the helical molecule bind differently …
We have designed a synthetic tetracationic metallo-supramolecular cylinder that targets the major groove of DNA with a binding constant in e …
13 results