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1977 1
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1999 3
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2003 1
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2005 2
2009 1
2010 2
2012 3
2013 4
2014 3
2015 1
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84 results

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Page 1
Tofacitinib in juvenile idiopathic arthritis: a double-blind, placebo-controlled, withdrawal phase 3 randomised trial.
Ruperto N, Brunner HI, Synoverska O, Ting TV, Mendoza CA, Spindler A, Vyzhga Y, Marzan K, Grebenkina L, Tirosh I, Imundo L, Jerath R, Kingsbury DJ, Sozeri B, Vora SS, Prahalad S, Zholobova E, Butbul Aviel Y, Chasnyk V, Lerman M, Nanda K, Schmeling H, Tory H, Uziel Y, Viola DO, Posner HB, Kanik KS, Wouters A, Chang C, Zhang R, Lazariciu I, Hsu MA, Suehiro RM, Martini A, Lovell DJ; Paediatric Rheumatology International Trials Organisation (PRINTO) and Pediatric Rheumatology Collaborative Study Group (PRCSG). Ruperto N, et al. Lancet. 2021 Nov 27;398(10315):1984-1996. doi: 10.1016/S0140-6736(21)01255-1. Epub 2021 Nov 9. Lancet. 2021. PMID: 34767764 Free article. Clinical Trial.
Cyclic nucleotide phosphodiesterases as drug targets.
Kelly MP, Nikolaev VO, Gobejishvili L, Lugnier C, Hesslinger C, Nickolaus P, Kass DA, Pereira de Vasconcelos W, Fischmeister R, Brocke S, Epstein PM, Piazza GA, Keeton AB, Zhou G, Abdel-Halim M, Abadi AH, Baillie GS, Giembycz MA, Bolger G, Snyder G, Tasken K, Saidu NEB, Schmidt M, Zaccolo M, Schermuly RT, Ke H, Cote RH, Mohammadi Jouabadi S, Roks AJM. Kelly MP, et al. Pharmacol Rev. 2025 May;77(3):100042. doi: 10.1016/j.pharmr.2025.100042. Epub 2025 Jan 22. Pharmacol Rev. 2025. PMID: 40081105 Free article. Review.
Odronextamab monotherapy in R/R DLBCL after progression with CAR T-cell therapy: primary analysis of the ELM-1 study.
Topp MS, Matasar M, Allan JN, Ansell SM, Barnes JA, Arnason JE, Michot JM, Goldschmidt N, O'Brien SM, Abadi U, Avivi I, Cheng Y, Flink DM, Zhu M, Brouwer-Visser J, Chaudhry A, Mohamed H, Ambati S, Crombie JL. Topp MS, et al. Blood. 2025 Apr 3;145(14):1498-1509. doi: 10.1182/blood.2024027044. Blood. 2025. PMID: 39786390 Free PMC article. Clinical Trial.
Carnitine palmitoyltransferase deficiencies.
Bonnefont JP, Demaugre F, Prip-Buus C, Saudubray JM, Brivet M, Abadi N, Thuillier L. Bonnefont JP, et al. Mol Genet Metab. 1999 Dec;68(4):424-40. doi: 10.1006/mgme.1999.2938. Mol Genet Metab. 1999. PMID: 10607472 Review.
While CPT2 is a ubiquitous protein, two tissue-specific CPT1 isoforms-the so-called "liver" (L) and "muscle" (M) CPT1s-have been shown to exist. Amino acid and cDNA nucleotide sequences have been identified for all of these proteins. ...Two L-CPT1 mutations have been repor …
While CPT2 is a ubiquitous protein, two tissue-specific CPT1 isoforms-the so-called "liver" (L) and "muscle" (M) CPT1s-have been show …
Synovial tissue atlas in juvenile idiopathic arthritis reveals pathogenic niches associated with disease severity.
Bolton C, Mahony CB, Clay E, Nisa PR, Lomholt S, Hackland A, Chin PS, Smith CG, Alexiou V, Nguyen HD, Thyagarajan M, Sheikh Z, Davis P, Chippington S, Compeyrot-Lacassagne S, Davda S, Foley C, Turtsevich I, Ingledow B, Kupiec K, Kelly J, Hanlon MM, DiCarlo E, Jones LJ, Smith SL, Eyre S, Neag G, Kemble S, Madhu R, Palshikar MG, Korsunsky I, Gao C, Tran M, Dendrou C, Buckley CD, Coles MC, Raza K; MAPJAG Study Group; Gravallese E, Filer A, Wei K, Al-Abadi E, Rosser EC, Wedderburn LR, Croft AP; Multiomic Analysis of Paediatric Joint and Gut inflammation (MAPJAG) study group. Bolton C, et al. Sci Transl Med. 2025 Jul 2;17(805):eadt6050. doi: 10.1126/scitranslmed.adt6050. Epub 2025 Jul 2. Sci Transl Med. 2025. PMID: 40601776 Free PMC article.
The OHI index predicts early mortality from organ dysfunction and survival benefit from etoposide in patients with lymphoma.
Zoref-Lorenz A, Murakami J, Gurion R, Iyer SP, Abadi U, Cohen I, Goyal G, Mohamed S, Nikiforow S, Natour AEH, Weinstein S, Yacobovich J, Cho HL, Raanani P, Nagler A, Berliner N, Daver N, Itchaki G, Izraeli S, Ellis M, Jordan MB. Zoref-Lorenz A, et al. Blood Adv. 2025 Sep 9;9(17):4515-4525. doi: 10.1182/bloodadvances.2024014005. Blood Adv. 2025. PMID: 40249910 Free PMC article.
Design, synthesis, and metabolite identification of Tamoxifen esterase-activatable prodrugs.
Elbagoury RM, Shenouda MA, Elnakib HE, Wober J, Abadi AH, Ahmed NS. Elbagoury RM, et al. Bioorg Chem. 2023 Feb;131:106303. doi: 10.1016/j.bioorg.2022.106303. Epub 2022 Nov 28. Bioorg Chem. 2023. PMID: 36455483
Compound 3d [E/Z Benzyl-carbamic acid4-{2-benzyl-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-but-1-enyl}-phenyl ester] showed GI(50) = 0.09 M on MCF-7 and GI(50) = 1.84 M on MDA-MB231 cell lines. To further validate our hypothesis, metabolites of selected novel analogue …
Compound 3d [E/Z Benzyl-carbamic acid4-{2-benzyl-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-but-1-enyl}-phenyl ester] showed GI(50) = 0.09 M …
Long-term noise interferometry analysis in the northeast Pacific Ocean.
Ragland J, Abadi S, Sabra K. Ragland J, et al. J Acoust Soc Am. 2022 Jan;151(1):194. doi: 10.1121/10.0009232. J Acoust Soc Am. 2022. PMID: 35105001
The two hydrophones are separated by 3.2 km and are bottom-mounted at 1500 m. We demonstrate the ability of ambient noise interferometry to reliably detect multi-path arrivals in the deep ocean from bottom-mounted hydrophones. ...
The two hydrophones are separated by 3.2 km and are bottom-mounted at 1500 m. We demonstrate the ability of ambient noise interferome …
84 results