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Coupling of physical extraction and mathematical filtration in spectrophotometric analysis of natural therapy essential for prophylaxis and treatment of COVID-19 infection - Comparative study along with greenness evaluation.
Morgan EM, Boltia SA, Fayez YM, Abdelkawy M, Lotfy HM. Morgan EM, et al. Heliyon. 2023 Jun;9(6):e16284. doi: 10.1016/j.heliyon.2023.e16284. Epub 2023 May 18. Heliyon. 2023. PMID: 37235204 Free PMC article.
Vitamin C was resolved through physical extraction using de-ionized water while DIO and HSP were extracted via spectrophotometric methods using two different solvents [0.1 M NaOH or solvent blend consisting of DMSO and methanol (1:1)]. ...C was successfully analyzed in de- …
Vitamin C was resolved through physical extraction using de-ionized water while DIO and HSP were extracted via spectrophotometric methods us …
The metabolomic analysis of five Mentha species: cytotoxicity, anti-Helicobacter assessment, and the development of polymeric micelles for enhancing the anti-Helicobacter activity.
Bakr RO, Tawfike A, El-Gizawy HA, Tawfik N, Abdelmohsen UR, Abdelwahab MF, Alshareef WA, Fayez SM, El-Mancy SMS, El-Fishawy AM, Abdelkawy MA, Fayed MAA. Bakr RO, et al. RSC Adv. 2021 Feb 12;11(13):7318-7330. doi: 10.1039/d0ra09334c. eCollection 2021 Feb 10. RSC Adv. 2021. PMID: 35423273 Free PMC article.
This study used the metabolomics examination of five Mentha species (M. suaveolens, M. sylvestris, M. piperita, M. longifolia, and M. viridis) to justify their cytotoxicity and their anti-Helicobacter effects. ...OPLS-DA and dereplication studie …
This study used the metabolomics examination of five Mentha species (M. suaveolens, M. sylvestris, M. piperita, M
One-step sonochemical fabrication of biomass-derived porous hard carbons; towards tuned-surface anodes of sodium-ion batteries.
Ghani U, Iqbal N, Aboalhassan AA, Liu B, Aftab T, Zada I, Ullah F, Gu J, Li Y, Zhu S, Liu Q. Ghani U, et al. J Colloid Interface Sci. 2022 Apr;611:578-587. doi: 10.1016/j.jcis.2021.12.104. Epub 2021 Dec 21. J Colloid Interface Sci. 2022. PMID: 34971968
In contrast, conventional activation lacks these features under the same carbonization/activation parameters. The high porosity (1599 m(2)/g), rich functional groups (O = 8.10%, N = 0.95%), and well-connected nanoporous network resulting from sonochemical activation, remar …
In contrast, conventional activation lacks these features under the same carbonization/activation parameters. The high porosity (1599 m
Potential Anticancer Activity of the Furanocoumarin Derivative Xanthotoxin Isolated from Ammi majus L. Fruits: In Vitro and In Silico Studies.
Issa MY, Elshal MF, Fathallah N, Abdelkawy MA, Bishr M, Salama O, Abulfadl YS. Issa MY, et al. Molecules. 2022 Jan 29;27(3):943. doi: 10.3390/molecules27030943. Molecules. 2022. PMID: 35164207 Free PMC article.
Treating HepG2 cells with 6.9 g/mL of xanthotoxin induced significant changes in the DNA-cell cycle (increases in apoptotic pre-G1 and G2/M phases and a decrease in the S-phase). Xanthotoxin induced significant increase in Annexin-V-positive HepG2 cells both at the early a …
Treating HepG2 cells with 6.9 g/mL of xanthotoxin induced significant changes in the DNA-cell cycle (increases in apoptotic pre-G1 and G2/ …
Validated UPLC and TLC-Densitometry Stability Indicating Methods for the Determination of Rafoxanide in the Presence of Its Degradation Products.
Saad AS, Hamdy AM, Salama FM, Abdelkawy M. Saad AS, et al. J Chromatogr Sci. 2016 Oct 17;54(9):1661-1669. doi: 10.1093/chromsci/bmw112. J Chromatogr Sci. 2016. PMID: 27368343
The first is ultra-performance liquid chromatography method where separation was performed using acetonitrile:0.005 M potassium dihydrogen orthophosphate (pH 3.5) in a ratio of 80:20 by volume as a mobile phase using a Hypersil GOLD C8 column 1.9 mm (50 2.1 mm), UV detecti …
The first is ultra-performance liquid chromatography method where separation was performed using acetonitrile:0.005 M potassium dihyd …
Exquisite integration of quality-by-design and green analytical approaches for simultaneous determination of xylometazoline and antazoline in eye drops and rabbit aqueous humor, application to stability study.
Hussein OG, Ahmed DA, Rezk MR, Abdelkawy M, Rostom Y. Hussein OG, et al. J Pharm Biomed Anal. 2023 Oct 25;235:115598. doi: 10.1016/j.jpba.2023.115598. Epub 2023 Jul 23. J Pharm Biomed Anal. 2023. PMID: 37516064
Optimal chromatographic separation was attained by means of an XBridge C18 (4.6 250 mm, 5 m) column through isocratic elution using a mobile phase consists of phosphate buffer (pH 3.0): ethanol (60:40, by volume) at a 1.6 mL/min flow rate and 230.0 nm UV detection. ...
Optimal chromatographic separation was attained by means of an XBridge C18 (4.6 250 mm, 5 m) column through isocratic elution using a …
Effects of pharmacogenetics on pharmacokinetics and toxicity of doxorubicin in Egyptian breast cancer patients.
Ebaid NF, Abdelkawy KS, Shehata MA, Salem HF, Magdy G, Hussein RRS, Elbarbry F. Ebaid NF, et al. Xenobiotica. 2024 Mar;54(3):160-170. doi: 10.1080/00498254.2024.2330493. Epub 2024 Apr 2. Xenobiotica. 2024. PMID: 38491961
This study investigates the impact of single nucleotide polymorphisms in genes (SLC22A16 and CBR1) involved in the pharmacokinetics and toxicity of doxorubicin (DOX) in Egyptian female patients with breast cancer.Patients administered DOX (60 mg/m(2)) for 4 cycles every 3 …
This study investigates the impact of single nucleotide polymorphisms in genes (SLC22A16 and CBR1) involved in the pharmacokinetics and toxi …
Light curve analysis and evolutionary status of four newly identified short-period eclipsing binaries.
Darwish MS, Abdelkawy AGA, Hamed GM. Darwish MS, et al. Sci Rep. 2024 Feb 18;14(1):3998. doi: 10.1038/s41598-024-54289-1. Sci Rep. 2024. PMID: 38369534 Free PMC article.
The obtained parameters in addition to a list of previously published data are then utilized to derive an updated Mass-Luminosity relation (M-L) for both A and W-type eclipsing W UMa systems. A comparison with previously published relations reveals that the majority of the …
The obtained parameters in addition to a list of previously published data are then utilized to derive an updated Mass-Luminosity relation ( …
Kidney dimensions at sonography are correlated with glomerular filtration rate in renal transplant recipients and in kidney donors.
Paleologo G, Abdelkawy H, Barsotti M, Basha A, Bernabini G, Bianchi A, Caprio F, Emad A, Grassi G, Nerucci B, Tregnaghi C, Rizzo G, Donadio C. Paleologo G, et al. Transplant Proc. 2007 Jul-Aug;39(6):1779-81. doi: 10.1016/j.transproceed.2007.05.003. Transplant Proc. 2007. PMID: 17692610
GFR (urinary clearance of (99m)Tc-DTPA), S Cr, and S Cys were measured in 33 donors (28 females [F], 5 males [M]; SCr, 0.81-1.90 mg/dL) and 30 recipients (8 F, 22 M; SCr, 0.96-2.42 mg/dL). ...
GFR (urinary clearance of (99m)Tc-DTPA), S Cr, and S Cys were measured in 33 donors (28 females [F], 5 males [M]; SCr, 0.81-1.90 mg/d …
Validated chromatographic methods for simultaneous determination of tolfenamic acid and its major impurities.
Abdelwahab NS, Ali NW, Zaki MM, Abdelkawy M. Abdelwahab NS, et al. J Chromatogr Sci. 2015 Apr;53(4):484-91. doi: 10.1093/chromsci/bmu071. Epub 2014 Jul 12. J Chromatogr Sci. 2015. PMID: 25016532
The developed RP-HPLC depended on chromatographic separation of the studied drugs on a C18 column using 0.05 M KH2PO4 buffer (pH 3):acetonitrile (45:55, v/v) as a mobile phase delivered at constant flow rate of 1 mL min(-1) with UV detection at 230 nm. ...
The developed RP-HPLC depended on chromatographic separation of the studied drugs on a C18 column using 0.05 M KH2PO4 buffer (pH 3):a …
11 results