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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 2
2001 1
2009 1
2011 1
2013 2
2014 3
2015 4
2016 2
2017 5
2018 7
2019 6
2020 3
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34 results
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Page 1
Phase II trial of AKT inhibitor MK-2206 in patients with advanced breast cancer who have tumors with PIK3CA or AKT mutations, and/or PTEN loss/PTEN mutation.
Xing Y, Lin NU, Maurer MA, Chen H, Mahvash A, Sahin A, Akcakanat A, Li Y, Abramson V, Litton J, Chavez-MacGregor M, Valero V, Piha-Paul SA, Hong D, Do KA, Tarco E, Riall D, Eterovic AK, Wulf GM, Cantley LC, Mills GB, Doyle LA, Winer E, Hortobagyi GN, Gonzalez-Angulo AM, Meric-Bernstam F. Xing Y, et al. Breast Cancer Res. 2019 Jul 5;21(1):78. doi: 10.1186/s13058-019-1154-8. Breast Cancer Res. 2019. PMID: 31277699 Free PMC article. Clinical Trial.
Secondary endpoints were 6-month progression-free survival (6 m PFS), predictive and pharmacodynamic markers, safety, and tolerability. ...ORR was 0% and 6 m PFS was 11% (1/9), observed in a patient with triple-negative breast cancer and PTEN loss. The study was sto …
Secondary endpoints were 6-month progression-free survival (6 m PFS), predictive and pharmacodynamic markers, safety, and tolerabilit …
TAK228 enhances antitumor activity of eribulin in triple negative breast cancer.
Owusu-Brackett N, Evans KW, Akcakanat A, Yuca E, Tapia C, Rizvi YQ, Dumbrava EI, Janku F, Meric-Bernstam F. Owusu-Brackett N, et al. Oncotarget. 2019 Aug 20;10(49):5011-5019. doi: 10.18632/oncotarget.27082. eCollection 2019 Aug 20. Oncotarget. 2019. PMID: 31489111 Free PMC article.
The combination of TAK228 and eribulin did not enhance apoptosis but increased G2/M growth arrest. In vivo, TAK228 led to modest growth inhibition in TNBC patient-derived xenografts (PDXs) with no tumor regression observed. ...
The combination of TAK228 and eribulin did not enhance apoptosis but increased G2/M growth arrest. In vivo, TAK228 led to modest grow …
Neuroimaging Findings of Organic Acidemias and Aminoacidopathies.
Reddy N, Calloni SF, Vernon HJ, Boltshauser E, Huisman TAGM, Soares BP. Reddy N, et al. Radiographics. 2018 May-Jun;38(3):912-931. doi: 10.1148/rg.2018170042. Radiographics. 2018. PMID: 29757724 Review.
MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance.
Farrell AS, Joly MM, Allen-Petersen BL, Worth PJ, Lanciault C, Sauer D, Link J, Pelz C, Heiser LM, Morton JP, Muthalagu N, Hoffman MT, Manning SL, Pratt ED, Kendsersky ND, Egbukichi N, Amery TS, Thoma MC, Jenny ZP, Rhim AD, Murphy DJ, Sansom OJ, Crawford HC, Sheppard BC, Sears RC. Farrell AS, et al. Nat Commun. 2017 Nov 23;8(1):1728. doi: 10.1038/s41467-017-01967-6. Nat Commun. 2017. PMID: 29170413 Free PMC article.
Pressure-Controlled Ventilation with Volume Guarantee Compared to Volume-Controlled Ventilation with Equal Ratio in Obese Patients Undergoing Laparoscopic Hysterectomy.
Gad M, Gaballa K, Abdallah A, Abdelkhalek M, Zayed A, Nabil H. Gad M, et al. Anesth Essays Res. 2019 Apr-Jun;13(2):347-353. doi: 10.4103/aer.AER_82_19. Anesth Essays Res. 2019. PMID: 31198258 Free PMC article.
The present study aimed to compare the impact of pressure-controlled ventilation with volume-guaranteed (PCV-VG) and volume-controlled ventilation (VCV) with equal ratio ventilation (ERV), i.e., I: E ratio of 1:1 on hemodynamics, respiratory mechanics, and oxygenati …
The present study aimed to compare the impact of pressure-controlled ventilation with volume-guaranteed (PCV-VG) and volume-controlled venti …
Antiarrhythmic Drugs or Catheter Ablation in the Management of Ventricular Tachyarrhythmias in Patients With Implantable Cardioverter-Defibrillators: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Kheiri B, Barbarawi M, Zayed Y, Hicks M, Osman M, Rashdan L, Kyi HH, Bachuwa G, Hassan M, Stecker EC, Nazer B, Bhatt DL. Kheiri B, et al. Circ Arrhythm Electrophysiol. 2019 Nov;12(11):e007600. doi: 10.1161/CIRCEP.119.007600. Epub 2019 Nov 8. Circ Arrhythm Electrophysiol. 2019. PMID: 31698933
Halogenated flame retardants and organophosphate esters in the air of electronic waste recycling facilities: Evidence of high concentrations and multiple exposures.
Gravel S, Lavoué J, Bakhiyi B, Diamond ML, Jantunen LM, Lavoie J, Roberge B, Verner MA, Zayed J, Labrèche F. Gravel S, et al. Environ Int. 2019 Jul;128:244-253. doi: 10.1016/j.envint.2019.04.027. Epub 2019 May 3. Environ Int. 2019. PMID: 31059919 Free article.
BACKGROUND: In response to a worldwide increase in production of electronic waste, the e-recycling industry is rapidly rowing. ...The most detected chemical group of FRs in e-recycling was PBDEs with geometric mean sums of all congeners ranging from 120 to 5100 ng/ …
BACKGROUND: In response to a worldwide increase in production of electronic waste, the e-recycling industry is rapidly rowing. ...The …
Congenital abnormalities of the posterior fossa.
Bosemani T, Orman G, Boltshauser E, Tekes A, Huisman TA, Poretti A. Bosemani T, et al. Radiographics. 2015 Jan-Feb;35(1):200-20. doi: 10.1148/rg.351140038. Radiographics. 2015. PMID: 25590398 Free article. Review.
Quinazolinone-Amino Acid Hybrids as Dual Inhibitors of EGFR Kinase and Tubulin Polymerization.
Zayed MF, Rateb HS, Ahmed S, Khaled OA, Ibrahim SRM. Zayed MF, et al. Molecules. 2018 Jul 12;23(7):1699. doi: 10.3390/molecules23071699. Molecules. 2018. PMID: 30002297 Free PMC article.
New derivative E (IC(50) = 0.43 ± 0.02 µM) showed higher activity than the reference drug erlotinib (IC(50) = 2.55 ± 0.19 µM) against MDA-MBA-231. ...
New derivative E (IC(50) = 0.43 ± 0.02 µM) showed higher activity than the reference drug erlotinib (IC(50) = 2.55 ± 0.19 µM) against …
Insects with similar social complexity show convergent patterns of adaptive molecular evolution.
Dogantzis KA, Harpur BA, Rodrigues A, Beani L, Toth AL, Zayed A. Dogantzis KA, et al. Sci Rep. 2018 Jul 10;8(1):10388. doi: 10.1038/s41598-018-28489-5. Sci Rep. 2018. PMID: 29991733 Free PMC article.
This species triad allowed us to study molecular evolution across a gradient of social complexity (Polistes < Bombus < Apis) and compare species pairs that have similar (i.e. Polistes and Bombus) or different (i.e. Polistes and Apis) life histories, while cont …
This species triad allowed us to study molecular evolution across a gradient of social complexity (Polistes < Bombus < Apis) and compa …
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