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Page 1
A comprehensive library of human transcription factors for cell fate engineering.
Ng AHM, Khoshakhlagh P, Rojo Arias JE, Pasquini G, Wang K, Swiersy A, Shipman SL, Appleton E, Kiaee K, Kohman RE, Vernet A, Dysart M, Leeper K, Saylor W, Huang JY, Graveline A, Taipale J, Hill DE, Vidal M, Melero-Martin JM, Busskamp V, Church GM. Ng AHM, et al. Nat Biotechnol. 2021 Apr;39(4):510-519. doi: 10.1038/s41587-020-0742-6. Epub 2020 Nov 30. Nat Biotechnol. 2021. PMID: 33257861 Free PMC article.
Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses.
Chan YK, Wang SK, Chu CJ, Copland DA, Letizia AJ, Costa Verdera H, Chiang JJ, Sethi M, Wang MK, Neidermyer WJ Jr, Chan Y, Lim ET, Graveline AR, Sanchez M, Boyd RF, Vihtelic TS, Inciong RGCO, Slain JM, Alphonse PJ, Xue Y, Robinson-McCarthy LR, Tam JM, Jabbar MH, Sahu B, Adeniran JF, Muhuri M, Tai PWL, Xie J, Krause TB, Vernet A, Pezone M, Xiao R, Liu T, Wang W, Kaplan HJ, Gao G, Dick AD, Mingozzi F, McCall MA, Cepko CL, Church GM. Chan YK, et al. Sci Transl Med. 2021 Feb 10;13(580):eabd3438. doi: 10.1126/scitranslmed.abd3438. Sci Transl Med. 2021. PMID: 33568518 Free PMC article.
A backpack-based myeloid cell therapy for multiple sclerosis.
Kapate N, Dunne M, Kumbhojkar N, Prakash S, Wang LL, Graveline A, Park KS, Chandran Suja V, Goyal J, Clegg JR, Mitragotri S. Kapate N, et al. Proc Natl Acad Sci U S A. 2023 Apr 25;120(17):e2221535120. doi: 10.1073/pnas.2221535120. Epub 2023 Apr 19. Proc Natl Acad Sci U S A. 2023. PMID: 37075071 Free PMC article.
A Modular Biomaterial Scaffold-Based Vaccine Elicits Durable Adaptive Immunity to Subunit SARS-CoV-2 Antigens.
Langellotto F, Dellacherie MO, Yeager C, Ijaz H, Yu J, Cheng CA, Dimitrakakis N, Seiler BT, Gebre MS, Gilboa T, Johnson R, Storm N, Bardales S, Graveline A, White D, Tringides CM, Cartwright MJ, Doherty EJ, Honko A, Griffiths A, Barouch DH, Walt DR, Mooney DJ. Langellotto F, et al. Adv Healthc Mater. 2021 Nov;10(22):e2101370. doi: 10.1002/adhm.202101370. Epub 2021 Oct 4. Adv Healthc Mater. 2021. PMID: 34605223 Free PMC article.
A single combination gene therapy treats multiple age-related diseases.
Davidsohn N, Pezone M, Vernet A, Graveline A, Oliver D, Slomovic S, Punthambaker S, Sun X, Liao R, Bonventre JV, Church GM. Davidsohn N, et al. Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23505-23511. doi: 10.1073/pnas.1910073116. Epub 2019 Nov 4. Proc Natl Acad Sci U S A. 2019. PMID: 31685628 Free PMC article.
Which outcomes should always be measured in intervention studies for improving work participation for people with a health problem? An international multistakeholder Delphi study to develop a core outcome set for Work participation (COS for Work).
Ravinskaya M, Verbeek JH, Langendam M, Madan I, Verstappen SMM, Kunz R, Hulshof CTJ, Hoving JL; Delphi participants. Ravinskaya M, et al. BMJ Open. 2023 Feb 15;13(2):e069174. doi: 10.1136/bmjopen-2022-069174. BMJ Open. 2023. PMID: 36792339 Free PMC article.
An Environmental Scan and Appraisal of Patient Online Resources for Managing Rheumatoid Arthritis Flares.
Subdar S, Hoens AM, White K, Hartfeld NMS, Dhiman K, Duffey K, Heath CE, Lamoureux G, Graveline C, Davidson E, Hazlewood G, Lacaille D, Lopatina E, Barber MRW, Then KL, Crump T, Zafar S, Manske SL, Charlton A, Osinski K, Fifi-Mah A, Mosher D, Barber CEH. Subdar S, et al. J Rheumatol. 2024 Jun 1;51(6):577-586. doi: 10.3899/jrheum.2023-1025. J Rheumatol. 2024. PMID: 38490667
Evidence for covalent attachment of phospholipid to the capsular polysaccharide of Haemophilus influenzae type b.
Kuo JS, Doelling VW, Graveline JF, McCoy DW. Kuo JS, et al. J Bacteriol. 1985 Aug;163(2):769-73. doi: 10.1128/jb.163.2.769-773.1985. J Bacteriol. 1985. PMID: 3926752 Free PMC article.
The radioactivity of this preparation could not be dissociated from PRP by treatment with chloroform-methanol, 6 M urea, sodium dodecyl sulfate, or Zwittergent. Only after acid, alkaline, or phospholipase A2 treatment of PRP labeled with [3H]palmitate or [3H]palmitate and …
The radioactivity of this preparation could not be dissociated from PRP by treatment with chloroform-methanol, 6 M urea, sodium dodec …
Inhibition of human pancreatic elastase II activity on human aortic elastin by human alpha 2-macroglobulin.
Graveline J, Garret M, Zourgui L, Lambin P, Lefebvre F, Rabaud M. Graveline J, et al. Experientia. 1986 Jul 15;42(7):830-3. doi: 10.1007/BF01941542. Experientia. 1986. PMID: 2426137
We demonstrated that two moles of alpha 2-M are required to inhibit one mole of HPEII when the enzyme is added to a mixture of elastin and alpha 2-M. In addition, when the elastase-alpha 2-M complex is prepared under some circumstances, it exhibits an elastin …
We demonstrated that two moles of alpha 2-M are required to inhibit one mole of HPEII when the enzyme is added to a mixture of elasti …