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Year Number of Results
1978 1
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1984 1
1985 1
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1989 2
1990 1
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1992 10
1993 5
1994 11
1995 11
1996 22
1997 8
1998 11
1999 13
2000 13
2001 18
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2003 35
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2005 71
2006 56
2007 68
2008 73
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2025 1

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3,841 results

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Page 1
Induction of immortal-like and functional CAR T cells by defined factors.
Wang L, Jin G, Zhou Q, Liu Y, Zhao X, Li Z, Yin N, Peng M. Wang L, et al. J Exp Med. 2024 May 6;221(5):e20232368. doi: 10.1084/jem.20232368. Epub 2024 Mar 26. J Exp Med. 2024. PMID: 38530240 Free PMC article.
Long-term antitumor efficacy of chimeric antigen receptor (CAR) T cells depends on their functional persistence in vivo. T cells with stem-like properties show better persistence, but factors conferring bona fide stemness to T cells remain to be determined. . …
Long-term antitumor efficacy of chimeric antigen receptor (CAR) T cells depends on their functional persistence in vivo. T cel …
METTL3-m(6)A-Rubicon axis inhibits autophagy in nonalcoholic fatty liver disease.
Peng Z, Gong Y, Wang X, He W, Wu L, Zhang L, Xiong L, Huang Y, Su L, Shi P, Cao X, Liu R, Li Y, Xiao H. Peng Z, et al. Mol Ther. 2022 Feb 2;30(2):932-946. doi: 10.1016/j.ymthe.2021.09.016. Epub 2021 Sep 20. Mol Ther. 2022. PMID: 34547464 Free PMC article.
However, the role of m(6)A modification in autophagy in nonalcoholic fatty liver disease (NAFLD) remains largely unknown. ...Mechanistically, METTL3 directly bound to Rubicon mRNA and mediated the m(6)A modification, while YTH N6-methyladenosine RNA binding protein …
However, the role of m(6)A modification in autophagy in nonalcoholic fatty liver disease (NAFLD) remains largely unknown. ...Mechanis …
N(6)-methyladenosine (m(6)A) in 18S rRNA promotes fatty acid metabolism and oncogenic transformation.
Peng H, Chen B, Wei W, Guo S, Han H, Yang C, Ma J, Wang L, Peng S, Kuang M, Lin S. Peng H, et al. Nat Metab. 2022 Aug;4(8):1041-1054. doi: 10.1038/s42255-022-00622-9. Epub 2022 Aug 23. Nat Metab. 2022. PMID: 35999469
Here, we show that the 18S rRNA N(6)-methyladenosine (m(6)A) methyltransferase complex METTL5-TRMT112 is upregulated in various cancer types and correlated with poor prognosis. ...Mechanistically, depletion of METTL5-mediated 18S rRNA m(6)A modification results in i …
Here, we show that the 18S rRNA N(6)-methyladenosine (m(6)A) methyltransferase complex METTL5-TRMT112 is upregulated in various cance …
Polystyrene microplastics induce size-dependent multi-organ damage in mice: Insights into gut microbiota and fecal metabolites.
Zhang Z, Chen W, Chan H, Peng J, Zhu P, Li J, Jiang X, Zhang Z, Wang Y, Tan Z, Peng Y, Zhang S, Lin K, Yung KK. Zhang Z, et al. J Hazard Mater. 2024 Jan 5;461:132503. doi: 10.1016/j.jhazmat.2023.132503. Epub 2023 Sep 6. J Hazard Mater. 2024. PMID: 37717443
In this study, we attempted to examine the systemic toxicity of polystyrene MPs of different sizes (0.5 m MP1 and 5 m MP2) in C57BL/6 J mice. After the mice were given oral gavage of MPs for 8 consecutive weeks, histopathology and molecular biology assays, 16 S rRNA …
In this study, we attempted to examine the systemic toxicity of polystyrene MPs of different sizes (0.5 m MP1 and 5 m MP2) in …
T Cells in Pathogenic Infections.
Peng HY, Song J. Peng HY, et al. Pathogens. 2023 Apr 10;12(4):578. doi: 10.3390/pathogens12040578. Pathogens. 2023. PMID: 37111464 Free PMC article.
T cells are essential to cell-mediated immunity during bacterial, viral, and fungal infections, and immune-related diseases [...]....
T cells are essential to cell-mediated immunity during bacterial, viral, and fungal infections, and immune-related diseases [...]....
N6-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis.
Chen B, Huang Y, He S, Yu P, Wu L, Peng H. Chen B, et al. Cell Chem Biol. 2023 Feb 16;30(2):144-158.e10. doi: 10.1016/j.chembiol.2023.01.006. Cell Chem Biol. 2023. PMID: 36800991 Free article.
Aberrant N(6)-methyladenosine (m(6)A) modification on mRNA is correlated with cancer progression. However, the role of m(6)A on ribosomal RNA (rRNA) in cancer remains poorly understood. Our current study reveals that METTL5/TRMT112 and their mediated m(6)A mo …
Aberrant N(6)-methyladenosine (m(6)A) modification on mRNA is correlated with cancer progression. However, the role of m(6)A o …
Endothelial Response to Pathophysiological Stress.
Peng Z, Shu B, Zhang Y, Wang M. Peng Z, et al. Arterioscler Thromb Vasc Biol. 2019 Nov;39(11):e233-e243. doi: 10.1161/ATVBAHA.119.312580. Epub 2019 Oct 23. Arterioscler Thromb Vasc Biol. 2019. PMID: 31644356 Review.
Metabolic Reprogramming and Reactive Oxygen Species in T Cell Immunity.
Peng HY, Lucavs J, Ballard D, Das JK, Kumar A, Wang L, Ren Y, Xiong X, Song J. Peng HY, et al. Front Immunol. 2021 Mar 31;12:652687. doi: 10.3389/fimmu.2021.652687. eCollection 2021. Front Immunol. 2021. PMID: 33868291 Free PMC article. Review.
The imbalance between ROS generation and scavenging could result in severe damage to the cells and potential cell death, ultimately leading to T cell-related diseases. Interestingly, ROS play an essential role in T cell immunity. Here, we introduce the important con …
The imbalance between ROS generation and scavenging could result in severe damage to the cells and potential cell death, ultimately leading …
Meet the extended Segatella copri complex.
Peng Y, Tun HM. Peng Y, et al. Cell Host Microbe. 2023 Nov 8;31(11):1766-1769. doi: 10.1016/j.chom.2023.10.009. Cell Host Microbe. 2023. PMID: 37944487 Free article.
Mycoplasma genitalium Protein of Adhesion Suppresses T Cell Activation via CypA-CaN-NFAT Pathway.
Luo D, Luo H, Yan X, Lei A, He J, Liao Y, Peng K, Li X, Ye Y, Chen L, Zeng Z, Xiao H, Zeng Y. Luo D, et al. Microbiol Spectr. 2023 Jun 15;11(3):e0450322. doi: 10.1128/spectrum.04503-22. Epub 2023 Apr 19. Microbiol Spectr. 2023. PMID: 37074201 Free PMC article.
Moreover, rMgPa inhibited the expressions of IFN-gamma, IL-2, CD25, and CD69 in primary mouse T cells. Likewise, the expressions of these T cells activation-related molecules in CypA-siRNA-transfected cells and CypA(-/-) mouse primary T cell was strengthened …
Moreover, rMgPa inhibited the expressions of IFN-gamma, IL-2, CD25, and CD69 in primary mouse T cells. Likewise, the expressions of t …
3,841 results