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Showing results for M. sadeghizadeh
Your search for M. sadeghizade retrieved no results
Mitochondria-Targeted Polyamidoamine Dendrimer-Curcumin Construct for Hepatocellular Cancer Treatment.
Kianamiri S, Dinari A, Sadeghizadeh M, Rezaei M, Daraei B, Bahsoun NE, Nomani A. Kianamiri S, et al. Mol Pharm. 2020 Dec 7;17(12):4483-4498. doi: 10.1021/acs.molpharmaceut.0c00566. Epub 2020 Nov 18. Mol Pharm. 2020. PMID: 33205974
Our findings showed that the targeted-dendrimeric curcumin (TDC) could successfully deliver and colocalize the drug to the mitochondria of the cancer cells, and selectively induce a potent apoptosis and cell cycle arrest at G2/M. Moreover, at a low curcumin dose of less th …
Our findings showed that the targeted-dendrimeric curcumin (TDC) could successfully deliver and colocalize the drug to the mitochondria of t …
Radiosensitizing effect of dendrosomal nanoformulation of curcumin on cancer cells.
Varnamkhasti TJ, Jafarzadeh M, Sadeghizadeh M, Aghili M. Varnamkhasti TJ, et al. Pharmacol Rep. 2022 Aug;74(4):718-735. doi: 10.1007/s43440-022-00383-y. Epub 2022 Jul 10. Pharmacol Rep. 2022. PMID: 35819593
Further experiments then indicated that DNC could effectively induce G2/M phase cell cycle arrest and apoptosis following irradiation. Conformably, there was a decrement of CCND1 and CCNB1 expression, and an increment of P53, P21 expression. ...
Further experiments then indicated that DNC could effectively induce G2/M phase cell cycle arrest and apoptosis following irradiation …
Inhibition of HIV-1 infection with curcumin conjugated PEG-citrate dendrimer; a new nano formulation.
Ebrahimi S, Sadeghizadeh M, Aghasadeghi MR, Ardestani MS, Amini SA, Vahabpour R. Ebrahimi S, et al. BMC Complement Med Ther. 2024 Oct 2;24(1):350. doi: 10.1186/s12906-024-04634-8. BMC Complement Med Ther. 2024. PMID: 39358802 Free PMC article.
Inhibition of HIV-1 at concentrations much lower than CC50 (300 M) indicates a high potential of curcumin-dendrimer conjugate against this virus. CONCLUSION: Thereby, curcumin-dendrimer conjugate proves to be a promising tool to use in HIV-1 therapy....
Inhibition of HIV-1 at concentrations much lower than CC50 (300 M) indicates a high potential of curcumin-dendrimer conjugate against …
Remarkable improvements of a neutral protease activity and stability share the same structural origins.
Asghari SM, Pazhang M, Ehtesham S, Karbalaei-Heidari HR, Taghdir M, Sadeghizadeh M, Naderi-Manesh H, Khajeh K. Asghari SM, et al. Protein Eng Des Sel. 2010 Aug;23(8):599-606. doi: 10.1093/protein/gzq031. Epub 2010 May 31. Protein Eng Des Sel. 2010. PMID: 20513706
Four out of seven point mutations are able to promote both activity and thermostability individually and combinedly. The catalytic efficiency (k(cat)/K(m)) of four-amino acid substituted variant (quadruple mutant) at 60 degrees C is 18-fold higher than wild type, whereas a …
Four out of seven point mutations are able to promote both activity and thermostability individually and combinedly. The catalytic efficienc …
Up-regulation of miR-21 decreases chemotherapeutic effect of dendrosomal curcumin in breast cancer cells.
Esmatabadi MJD, Farhangi B, Montazeri M, Monfared H, Sistani RN, Sadeghizadeh M. Esmatabadi MJD, et al. Iran J Basic Med Sci. 2017 Apr;20(4):350-359. doi: 10.22038/IJBMS.2017.8574. Iran J Basic Med Sci. 2017. PMID: 28804605 Free PMC article.
Furthermore, DNC induced a marked increase in the number of cells in sub G1/G1 phase and a decrease in G2/M phase of the cell cycle in both; but, we observed reverse results compared it, after transfection with miR-21 vector. ...
Furthermore, DNC induced a marked increase in the number of cells in sub G1/G1 phase and a decrease in G2/M phase of the cell cycle i …
20 results