The antisecretory effects of zaltidine, a novel long-acting H2-receptor antagonist, in healthy volunteers and in subjects with a past history of duodenal ulcer.
Laferla G, Buchanan N, Hearns J, Crean GP, McColl KE, Clucas AT.
Laferla G, et al.
Br J Clin Pharmacol. 1986 Oct;22(4):395-9. doi: 10.1111/j.1365-2125.1986.tb02908.x.
Br J Clin Pharmacol. 1986.
PMID: 2876724
Free PMC article.
Clinical Trial.
In eight healthy male volunteers single oral doses of 5 mg, 25 mg and 100 mg produced dose-related inhibition of basal and pentagastrin-stimulated acid output (M.A.O.) with an estimated ID50 of 40 mg for the latter. In eight subjects with duodenal ulceration single …
In eight healthy male volunteers single oral doses of 5 mg, 25 mg and 100 mg produced dose-related inhibition of basal and pentagastrin-stim …