Nelfinavir: An Old Ally in the COVID-19 Fight?
Gidari A, Sabbatini S, Pallotto C, Bastianelli S, Pierucci S, Busti C, Schiaroli E, Francisci D.
Gidari A, et al.
Microorganisms. 2022 Dec 14;10(12):2471. doi: 10.3390/microorganisms10122471.
Microorganisms. 2022.
PMID: 36557724
Free PMC article.
In this study, we used a Vero-E6-cell-based infection assay to investigate the in vitro activity of nelfinavir, molnupiravir, and remdesivir. Four strains of SARS-CoV-2 were tested: 20A.EU1, B.1.1.7, P.1, and B.1.617.2. All compounds reached micromolar/submicromolar EC50, …
In this study, we used a Vero-E6-cell-based infection assay to investigate the in vitro activity of nelfinavir, molnupiravir, and remdesivir …