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Page 1
Nelfinavir: An Old Ally in the COVID-19 Fight?
Gidari A, Sabbatini S, Pallotto C, Bastianelli S, Pierucci S, Busti C, Schiaroli E, Francisci D. Gidari A, et al. Microorganisms. 2022 Dec 14;10(12):2471. doi: 10.3390/microorganisms10122471. Microorganisms. 2022. PMID: 36557724 Free PMC article.
In this study, we used a Vero-E6-cell-based infection assay to investigate the in vitro activity of nelfinavir, molnupiravir, and remdesivir. Four strains of SARS-CoV-2 were tested: 20A.EU1, B.1.1.7, P.1, and B.1.617.2. All compounds reached micromolar/submicromolar EC50, …
In this study, we used a Vero-E6-cell-based infection assay to investigate the in vitro activity of nelfinavir, molnupiravir, and remdesivir …
Synergistic Activity of Remdesivir-Nirmatrelvir Combination on a SARS-CoV-2 In Vitro Model and a Case Report.
Gidari A, Sabbatini S, Schiaroli E, Bastianelli S, Pierucci S, Busti C, Saraca LM, Capogrossi L, Pasticci MB, Francisci D. Gidari A, et al. Viruses. 2023 Jul 19;15(7):1577. doi: 10.3390/v15071577. Viruses. 2023. PMID: 37515263 Free PMC article.
METHODS: A Vero E6 cell-based infection assay was used to investigate the in vitro activity of the remdesivir-nirmatrelvir combination. The SARS-CoV-2 strains tested were 20A.EU1, BA.1 and BA.5. After incubation, a viability assay was performed. ...
METHODS: A Vero E6 cell-based infection assay was used to investigate the in vitro activity of the remdesivir-nirmatrelvir combination. The …
Rarity of monodominance in hyperdiverse Amazonian forests.
Ter Steege H, Henkel TW, Helal N, Marimon BS, Marimon-Junior BH, Huth A, Groeneveld J, Sabatier D, Coelho LS, Filho DAL, Salomão RP, Amaral IL, Matos FDA, Castilho CV, Phillips OL, Guevara JE, Carim MJV, Cárdenas López D, Magnusson WE, Wittmann F, Irume MV, Martins MP, Guimarães JRDS, Molino JF, Bánki OS, Piedade MTF, Pitman NCA, Mendoza AM, Ramos JF, Luize BG, Moraes de Leão Novo EM, Núñez Vargas P, Silva TSF, Venticinque EM, Manzatto AG, Reis NFC, Terborgh J, Casula KR, Honorio Coronado EN, Montero JC, Feldpausch TR, Duque A, Costa FRC, Arboleda NC, Schöngart J, Killeen TJ, Vasquez R, Mostacedo B, Demarchi LO, Assis RL, Baraloto C, Engel J, Petronelli P, Castellanos H, de Medeiros MB, Quaresma A, Simon MF, Andrade A, Camargo JL, Laurance SGW, Laurance WF, Rincón LM, Schietti J, Sousa TR, de Sousa Farias E, Lopes MA, Magalhães JLL, Mendonça Nascimento HE, Lima de Queiroz H, Aymard C GA, Brienen R, Revilla JDC, Vieira ICG, Cintra BBL, Stevenson PR, Feitosa YO, Duivenvoorden JF, Mogollón HF, Araujo-Murakami A, Ferreira LV, Lozada JR, Comiskey JA, de Toledo JJ, Damasco G, Dávila N, Draper F, García-Villacorta R, Lopes A, Vicentini A, Alonso A, Dallmeier F, Gomes VHF, Lloyd J, Neill … See abstract for full author list ➔ Ter Steege H, et al. Sci Rep. 2019 Sep 25;9(1):13822. doi: 10.1038/s41598-019-50323-9. Sci Rep. 2019. PMID: 31554920 Free PMC article.
Hemoglobin Variant Profiles among Brazilian Quilombola Communities.
Santiago RP, Oliveira RM, Soares LF, Figueiredo CVB, Silva DO, Hurtado-Guerrero AF, Fiuza LM, Guarda CC, Adorno EV, Barbosa CG, Gonçalves MS. Santiago RP, et al. Hemoglobin. 2017 Mar;41(2):83-88. doi: 10.1080/03630269.2017.1321014. Epub 2017 Jun 7. Hemoglobin. 2017. PMID: 28589738 Clinical Trial.
All the participants had their Hb profiles evaluated. The Hb S (HBB: c.20A>T) variant was described in all the studied localities. However, the individuals in Bahia State had the highest frequency of the Hb C (HBB: c.19G>A) variant; individuals from Piaui State had a …
All the participants had their Hb profiles evaluated. The Hb S (HBB: c.20A>T) variant was described in all the studied localities. …
Tixagevimab/Cilgavimab: Still a Valid Prophylaxis against COVID-19 New Variants?
Gidari A, Sabbatini S, Bastianelli S, Pierucci S, Busti C, Svizzeretto E, Tommasi A, Pallotto C, Schiaroli E, Francisci D. Gidari A, et al. Viruses. 2024 Feb 25;16(3):354. doi: 10.3390/v16030354. Viruses. 2024. PMID: 38543720
It evaluates serum neutralization activity against different SARS-CoV-2 strains (20A.EU1, BA.5, BQ.1, XBB.1.5, XBB.1.16, and EG.5) before (T0), after 14 (T1), and after 30 (T2) days from the tixagevimab/cilgavimab injection. ...
It evaluates serum neutralization activity against different SARS-CoV-2 strains (20A.EU1, BA.5, BQ.1, XBB.1.5, XBB.1.16, and EG.5) be …
Cross-neutralization of SARS-CoV-2 B.1.1.7 and P.1 variants in vaccinated, convalescent and P.1 infected.
Gidari A, Sabbatini S, Bastianelli S, Pierucci S, Busti C, Monari C, Luciani Pasqua B, Dragoni F, Schiaroli E, Zazzi M, Francisci D. Gidari A, et al. J Infect. 2021 Oct;83(4):467-472. doi: 10.1016/j.jinf.2021.07.019. Epub 2021 Jul 25. J Infect. 2021. PMID: 34320390 Free PMC article.
METHODS: BNT162b2-elicited serum (N = 103), candidates as hyper-immune plasma donors (N = 90) and patients infected with the SARS-CoV-2 P1 variant (N = 22) were enrolled. Three strains of SARS-CoV-2 have been tested: 20A.EU1, B.1.1.7 (alpha) and P.1 (gamma). Neutralizing a …
METHODS: BNT162b2-elicited serum (N = 103), candidates as hyper-immune plasma donors (N = 90) and patients infected with the SARS-CoV-2 P1 v …
37 results