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Year Number of Results
2013 2
2014 3
2015 4
2016 9
2017 5
2018 5
2019 10
2020 9
2021 1
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46 results
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Page 1
Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation.
Cosin-Roger J, Simmen S, Melhem H, Atrott K, Frey-Wagner I, Hausmann M, de Vallière C, Spalinger MR, Spielmann P, Wenger RH, Zeitz J, Vavricka SR, Rogler G, Ruiz PA. Cosin-Roger J, et al. Among authors: spalinger mr. Nat Commun. 2017 Jul 24;8(1):98. doi: 10.1038/s41467-017-00213-3. Nat Commun. 2017. PMID: 28740109 Free PMC article.
PTPN2 Regulates Inflammasome Activation and Controls Onset of Intestinal Inflammation and Colon Cancer.
Spalinger MR, Manzini R, Hering L, Riggs JB, Gottier C, Lang S, Atrott K, Fettelschoss A, Olomski F, Kündig TM, Fried M, McCole DF, Rogler G, Scharl M. Spalinger MR, et al. Cell Rep. 2018 Feb 13;22(7):1835-1848. doi: 10.1016/j.celrep.2018.01.052. Cell Rep. 2018. PMID: 29444435 Free PMC article.
PTPN2 Regulates Interactions Between Macrophages and Intestinal Epithelial Cells to Promote Intestinal Barrier Function.
Spalinger MR, Sayoc-Becerra A, Santos AN, Shawki A, Canale V, Krishnan M, Niechcial A, Obialo N, Scharl M, Li J, Nair MG, McCole DF. Spalinger MR, et al. Gastroenterology. 2020 Nov;159(5):1763-1777.e14. doi: 10.1053/j.gastro.2020.07.004. Epub 2020 Jul 9. Gastroenterology. 2020. PMID: 32652144
Titanium dioxide nanoparticles exacerbate DSS-induced colitis: role of the NLRP3 inflammasome.
Ruiz PA, Morón B, Becker HM, Lang S, Atrott K, Spalinger MR, Scharl M, Wojtal KA, Fischbeck-Terhalle A, Frey-Wagner I, Hausmann M, Kraemer T, Rogler G. Ruiz PA, et al. Among authors: spalinger mr. Gut. 2017 Jul;66(7):1216-1224. doi: 10.1136/gutjnl-2015-310297. Epub 2016 Feb 4. Gut. 2017. PMID: 26848183 Free PMC article.
The JAK inhibitor tofacitinib rescues intestinal barrier defects caused by disrupted epithelial-macrophage interactions.
Spalinger MR, Sayoc-Becerra A, Ordookhanian C, Canale V, Santos AN, King SJ, Krishnan M, Nair MG, Scharl M, McCole DF. Spalinger MR, et al. J Crohns Colitis. 2020 Sep 10:jjaa182. doi: 10.1093/ecco-jcc/jjaa182. Online ahead of print. J Crohns Colitis. 2020. PMID: 32909045
The Role of Protein Tyrosine Phosphatases in Inflammasome Activation.
Spalinger MR, Schwarzfischer M, Scharl M. Spalinger MR, et al. Int J Mol Sci. 2020 Jul 31;21(15):5481. doi: 10.3390/ijms21155481. Int J Mol Sci. 2020. PMID: 32751912 Free PMC article. Review.
Elevated oxysterol levels in human and mouse livers reflect nonalcoholic steatohepatitis.
Raselli T, Hearn T, Wyss A, Atrott K, Peter A, Frey-Wagner I, Spalinger MR, Maggio EM, Sailer AW, Schmitt J, Schreiner P, Moncsek A, Mertens J, Scharl M, Griffiths WJ, Bueter M, Geier A, Rogler G, Wang Y, Misselwitz B. Raselli T, et al. Among authors: spalinger mr. J Lipid Res. 2019 Jul;60(7):1270-1283. doi: 10.1194/jlr.M093229. Epub 2019 May 21. J Lipid Res. 2019. PMID: 31113816 Free PMC article.
The EBI2-oxysterol axis promotes the development of intestinal lymphoid structures and colitis.
Wyss A, Raselli T, Perkins N, Ruiz F, Schmelczer G, Klinke G, Moncsek A, Roth R, Spalinger MR, Hering L, Atrott K, Lang S, Frey-Wagner I, Mertens JC, Scharl M, Sailer AW, Pabst O, Hersberger M, Pot C, Rogler G, Misselwitz B. Wyss A, et al. Among authors: spalinger mr. Mucosal Immunol. 2019 May;12(3):733-745. doi: 10.1038/s41385-019-0140-x. Epub 2019 Feb 11. Mucosal Immunol. 2019. PMID: 30742043 Free article.
Presence of PTPN2 SNP rs1893217 Enhances the Anti-inflammatory Effect of Spermidine.
Niechcial A, Butter M, Manz S, Obialo N, Bäbler K, van der Lely L, Lang S, Gottier C, McCole DF, Scharl M, Spalinger MR. Niechcial A, et al. Among authors: spalinger mr. Inflamm Bowel Dis. 2020 Jun 18;26(7):1038-1049. doi: 10.1093/ibd/izaa013. Inflamm Bowel Dis. 2020. PMID: 32031616
Protein tyrosine phosphatase non-receptor type 22 modulates colitis in a microbiota-dependent manner.
Spalinger MR, Schmidt TS, Schwarzfischer M, Hering L, Atrott K, Lang S, Gottier C, Geirnaert A, Lacroix C, Dai X, Rawlings DJ, Chan AC, von Mering C, Rogler G, Scharl M. Spalinger MR, et al. J Clin Invest. 2019 May 20;129(6):2527-2541. doi: 10.1172/JCI123263. eCollection 2019 May 20. J Clin Invest. 2019. PMID: 31107248 Free PMC article.
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