L-kynurenine/aryl hydrocarbon receptor pathway mediates brain damage after experimental stroke.
Cuartero MI, Ballesteros I, de la Parra J, Harkin AL, Abautret-Daly A, Sherwin E, Fernández-Salguero P, Corbí AL, Lizasoain I, Moro MA.
Cuartero MI, et al.
Circulation. 2014 Dec 2;130(23):2040-51. doi: 10.1161/CIRCULATIONAHA.114.011394. Epub 2014 Oct 30.
Circulation. 2014.
PMID: 25359166
Inhibition of cAMP response element-binding protein-dependent signaling may participate in the deleterious actions of AhR. Finally, we have also found that L-kynurenine, a tryptophan metabolite with AhR agonistic properties, is an endogenous ligand that mediates AhR activa …
Inhibition of cAMP response element-binding protein-dependent signaling may participate in the deleterious actions of AhR. Finally, we have …