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Page 1
Swarms of chemically modified antiviral siRNA targeting herpes simplex virus infection in human corneal epithelial cells.
PLoS Pathog. 2022 Jul 6;18(7):e1010688. doi: 10.1371/journal.ppat.1010688. eCollection 2022 Jul.
PLoS Pathog. 2022.
PMID: 35793357
Free PMC article.
Single therapeutic dose of an antiviral UL29 siRNA swarm diminishes symptoms and viral load of mice infected intranasally with HSV-1.
Lasanen T, Frejborg F, Lund LM, Nyman MC, Orpana J, Habib H, Alaollitervo S, Levanova AA, Poranen MM, Hukkanen V, Kalke K.
Lasanen T, et al. Among authors: nyman mc.
Smart Med. 2023 May 10;2(2):e20230009. doi: 10.1002/SMMD.20230009. eCollection 2023 May.
Smart Med. 2023.
PMID: 39188276
Free PMC article.
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Decorin Expression in Human Vulva Carcinoma: Oncosuppressive Effect of Decorin cDNA Transduction on Carcinoma Cells.
Nyman MC, Jokilammi AB, Boström PC, Kurki SH, Sainio AO, Grenman SE, Orte KJ, Hietanen SH, Elenius K, Järveläinen HT.
Nyman MC, et al.
J Histochem Cytochem. 2019 Jul;67(7):511-522. doi: 10.1369/0022155419845373. Epub 2019 Apr 22.
J Histochem Cytochem. 2019.
PMID: 31009269
Free PMC article.
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Herpes Simplex Virus Type 1 Clinical Isolates Respond to UL29-Targeted siRNA Swarm Treatment Independent of Their Acyclovir Sensitivity.
Kalke K, Lehtinen J, Gnjatovic J, Lund LM, Nyman MC, Paavilainen H, Orpana J, Lasanen T, Frejborg F, Levanova AA, Vuorinen T, Poranen MM, Hukkanen V.
Kalke K, et al. Among authors: nyman mc.
Viruses. 2020 Dec 13;12(12):1434. doi: 10.3390/v12121434.
Viruses. 2020.
PMID: 33322225
Free PMC article.
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Enzymatically synthesized 2'-fluoro-modified Dicer-substrate siRNA swarms against herpes simplex virus demonstrate enhanced antiviral efficacy and low cytotoxicity.
Levanova AA, Kalke KM, Lund LM, Sipari N, Sadeghi M, Nyman MC, Paavilainen H, Hukkanen V, Poranen MM.
Levanova AA, et al. Among authors: nyman mc.
Antiviral Res. 2020 Oct;182:104916. doi: 10.1016/j.antiviral.2020.104916. Epub 2020 Aug 13.
Antiviral Res. 2020.
PMID: 32798603
Free PMC article.
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Decorin in Human Colon Cancer: Localization In Vivo and Effect on Cancer Cell Behavior In Vitro.
Nyman MC, Sainio AO, Pennanen MM, Lund RJ, Vuorikoski S, Sundström JT, Järveläinen HT.
Nyman MC, et al.
J Histochem Cytochem. 2015 Sep;63(9):710-20. doi: 10.1369/0022155415590830. Epub 2015 May 22.
J Histochem Cytochem. 2015.
PMID: 26001829
Free PMC article.
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