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Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
Baden LR, El Sahly HM, Essink B, Kotloff K, Frey S, Novak R, Diemert D, Spector SA, Rouphael N, Creech CB, McGettigan J, Khetan S, Segall N, Solis J, Brosz A, Fierro C, Schwartz H, Neuzil K, Corey L, Gilbert P, Janes H, Follmann D, Marovich M, Mascola J, Polakowski L, Ledgerwood J, Graham BS, Bennett H, Pajon R, Knightly C, Leav B, Deng W, Zhou H, Han S, Ivarsson M, Miller J, Zaks T; COVE Study Group. Baden LR, et al. N Engl J Med. 2021 Feb 4;384(5):403-416. doi: 10.1056/NEJMoa2035389. Epub 2020 Dec 30. N Engl J Med. 2021. PMID: 33378609 Free PMC article. Clinical Trial.
Tumor monocyte content predicts immunochemotherapy outcomes in esophageal adenocarcinoma.
Carroll TM, Chadwick JA, Owen RP, White MJ, Kaplinsky J, Peneva I, Frangou A, Xie PF, Chang J, Roth A, Amess B, James SA, Rei M, Fuchs HS, McCann KJ, Omiyale AO, Jacobs BA, Lord SR, Norris-Bulpitt S, Dobbie ST, Griffiths L, Ramirez KA, Ricciardi T, Macri MJ, Ryan A, Venhaus RR, Van den Eynde BJ, Karydis I, Schuster-Böckler B, Middleton MR, Lu X; LUD2015-005 Project Team. Carroll TM, et al. Cancer Cell. 2023 Jul 10;41(7):1222-1241.e7. doi: 10.1016/j.ccell.2023.06.006. Cancer Cell. 2023. PMID: 37433281 Free PMC article.
De novo variants in the RNU4-2 snRNA cause a frequent neurodevelopmental syndrome.
Chen Y, Dawes R, Kim HC, Ljungdahl A, Stenton SL, Walker S, Lord J, Lemire G, Martin-Geary AC, Ganesh VS, Ma J, Ellingford JM, Delage E, D'Souza EN, Dong S, Adams DR, Allan K, Bakshi M, Baldwin EE, Berger SI, Bernstein JA, Bhatnagar I, Blair E, Brown NJ, Burrage LC, Chapman K, Coman DJ, Compton AG, Cunningham CA, D'Souza P, Danecek P, Délot EC, Dias KR, Elias ER, Elmslie F, Evans CA, Ewans L, Ezell K, Fraser JL, Gallacher L, Genetti CA, Goriely A, Grant CL, Haack T, Higgs JE, Hinch AG, Hurles ME, Kuechler A, Lachlan KL, Lalani SR, Lecoquierre F, Leitão E, Fevre AL, Leventer RJ, Liebelt JE, Lindsay S, Lockhart PJ, Ma AS, Macnamara EF, Mansour S, Maurer TM, Mendez HR, Metcalfe K, Montgomery SB, Moosajee M, Nassogne MC, Neumann S, O'Donoghue M, O'Leary M, Palmer EE, Pattani N, Phillips J, Pitsava G, Pysar R, Rehm HL, Reuter CM, Revencu N, Riess A, Rius R, Rodan L, Roscioli T, Rosenfeld JA, Sachdev R, Shaw-Smith CJ, Simons C, Sisodiya SM, Snell P, St Clair L, Stark Z, Stewart HS, Tan TY, Tan NB, Temple SEL, Thorburn DR, Tifft CJ, Uebergang E, VanNoy GE, Vasudevan P, Vilain E, Viskochil DH, Wedd L, Wheeler MT, White SM, Wojcik M, Wolfe LA, Wolfenson Z, Wright CF, Xiao C, Zocche D, Rube… See abstract for full author list ➔ Chen Y, et al. Nature. 2024 Aug;632(8026):832-840. doi: 10.1038/s41586-024-07773-7. Epub 2024 Jul 11. Nature. 2024. PMID: 38991538 Free PMC article.
Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of Blinded Phase.
El Sahly HM, Baden LR, Essink B, Doblecki-Lewis S, Martin JM, Anderson EJ, Campbell TB, Clark J, Jackson LA, Fichtenbaum CJ, Zervos M, Rankin B, Eder F, Feldman G, Kennelly C, Han-Conrad L, Levin M, Neuzil KM, Corey L, Gilbert P, Janes H, Follmann D, Marovich M, Polakowski L, Mascola JR, Ledgerwood JE, Graham BS, August A, Clouting H, Deng W, Han S, Leav B, Manzo D, Pajon R, Schödel F, Tomassini JE, Zhou H, Miller J; COVE Study Group. El Sahly HM, et al. N Engl J Med. 2021 Nov 4;385(19):1774-1785. doi: 10.1056/NEJMoa2113017. Epub 2021 Sep 22. N Engl J Med. 2021. PMID: 34551225 Free PMC article. Clinical Trial.
Static and Dynamic Lung Volumes in Swimmers and Their Ventilatory Response to Maximal Exercise.
Rosser-Stanford B, Backx K, Lord R, Williams EM. Rosser-Stanford B, et al. Lung. 2019 Feb;197(1):15-19. doi: 10.1007/s00408-018-0175-x. Epub 2018 Nov 2. Lung. 2019. PMID: 30390109
RESULTS: Swimmers had significantly larger FVC (6.2 0.6 l, 109 9% pred) than the other groups (5.6 0.5 l, 106 13% pred, 5.5 0.8, 99% pred, the sportsmen and recreational groups, respectively). ...While at peak exercise, all groups reached their ventilatory reserve ( …
RESULTS: Swimmers had significantly larger FVC (6.2 0.6 l, 109 9% pred) than the other groups (5.6 0.5 l, 106 13% pred, 5.5 0. …
The interplay between endothelial glycocalyx maturity and both the toxicity and intracellular uptake of charged nanoparticles.
Bridges CA, Fu L, Yeow J, Huang X, Jackson M, Kuchel RP, Sterling JD, Baker SM, Lord MS. Bridges CA, et al. Acta Biomater. 2025 Apr;196:293-306. doi: 10.1016/j.actbio.2025.03.012. Epub 2025 Mar 7. Acta Biomater. 2025. PMID: 40058617 Free article.
These nanoparticles are subsequently internalized. Similar results were seen with poly(L-arginine). A mature glycocalyx protects cells by reducing the toxicity of these cationic nanoparticles. In contrast, lipoic acid-functionalized gold nanoparticles are internalized by c …
These nanoparticles are subsequently internalized. Similar results were seen with poly(L-arginine). A mature glycocalyx protects cell …
C5 Palsy After Cervical Spine Surgery: A Multicenter Retrospective Review of 59 Cases.
Thompson SE, Smith ZA, Hsu WK, Nassr A, Mroz TE, Fish DE, Wang JC, Fehlings MG, Tannoury CA, Tannoury T, Tortolani PJ, Traynelis VC, Gokaslan Z, Hilibrand AS, Isaacs RE, Mummaneni PV, Chou D, Qureshi SA, Cho SK, Baird EO, Sasso RC, Arnold PM, Buser Z, Bydon M, Clarke MJ, De Giacomo AF, Derakhshan A, Jobse B, Lord EL, Lubelski D, Massicotte EM, Steinmetz MP, Smith GA, Pace J, Corriveau M, Lee S, Cha PI, Chatterjee D, Gee EL, Mayer EN, McBride OJ, Roe AK, Yanez MY, Stroh DA, Than KD, Riew KD. Thompson SE, et al. Global Spine J. 2017 Apr;7(1 Suppl):64S-70S. doi: 10.1177/2192568216688189. Epub 2017 Apr 1. Global Spine J. 2017. PMID: 28451494 Free PMC article.
Epidemiology and Outcomes of Vertebral Artery Injury in 16 582 Cervical Spine Surgery Patients: An AOSpine North America Multicenter Study.
Hsu WK, Kannan A, Mai HT, Fehlings MG, Smith ZA, Traynelis VC, Gokaslan ZL, Hilibrand AS, Nassr A, Arnold PM, Mroz TE, Bydon M, Massicotte EM, Ray WZ, Steinmetz MP, Smith GA, Pace J, Corriveau M, Lee S, Isaacs RE, Wang JC, Lord EL, Buser Z, Riew KD. Hsu WK, et al. Global Spine J. 2017 Apr;7(1 Suppl):21S-27S. doi: 10.1177/2192568216686753. Epub 2017 Apr 1. Global Spine J. 2017. PMID: 28451487 Free PMC article.
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