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Page 1
Gastrointestinal involvement in very early and established systemic sclerosis: insights from the SPRING-SIR national Italian registry.
Bonomi F, Bruni C, Peretti S, De Angelis R, Bajocchi G, Giuggioli D, Orlandi M, Zanframundo G, Foti R, Cuomo G, Ariani A, Rosato E, Lepri G, Girelli F, Riccieri V, Zanatta E, Bosello SL, Cavazzana I, Ingegnoli F, De Santis M, Cacciapaglia F, Murdaca G, Abignano G, Giorgio P, Della Rossa A, Caminiti M, Iuliano AM, Ciano G, Beretta L, Bagnato G, Lubrano E, De Andres I, Idolazzi L, Saracco M, Agnes C, Campochiaro C, Cipolletta E, Fornaro M, Lumetti F, Spinella A, Magnani L, De Luca G, Codullo V, Visalli E, Iandoli C, Gigante A, Pellegrino G, Pigatto E, Lazzaroni MG, De Lorenzis E, Mennillo G, Di Battista M, Pagano-Mariano G, Furini F, Vultaggio L, Parisi S, Peroni CL, Bianchi G, Fusaro E, Sebastiani GD, Govoni M, D'Angelo S, Cozzi F, Franceschini F, Guiducci S, Dagna L, Doria A, Salvarani C, D'Agostino MA, Iannone F, Ferri C, Matucci-Cerinic M, Bellando Randone S; SPRING-SIR (Systemic Sclerosis PRogression INvestiGation group of the Italian Society for Rheumatology). Bonomi F, et al. Among authors: saracco m. Rheumatology (Oxford). 2026 Jan 8;65(1):keaf457. doi: 10.1093/rheumatology/keaf457. Rheumatology (Oxford). 2026. PMID: 40911437 Free PMC article.
Elderly-onset systemic sclerosis defines a distinct clinical subset: analysis from the SPRING registry of the Italian Society for Rheumatology.
Tonutti A, Motta F, Bajocchi G, Bellando-Randone S, Bruni C, Orlandi M, Zanframundo G, Foti R, Cuomo G, Ariani A, Rosato E, Lepri G, Girelli F, Zanatta E, Bosello SL, Cavazzana I, Ingegnoli F, Cacciapaglia F, Murdaca G, Abignano G, Pettiti G, Della Rossa A, Caminiti M, Iuliano A, Ciano G, Beretta L, Bagnato G, Lubrano E, De Andres I, Idolazzi L, Saracco M, Agnes C, Campochiaro C, Nivuori M, Cipolletta E, Lumetti F, Spinella A, Cocchiara E, De Luca G, Codullo V, Visalli E, Iandoli C, Gigante A, Pellegrino G, Pigatto E, Lazzaroni MG, De Lorenzis E, Mennillo G, Di Battista M, Pagano-Mariano G, Furini F, Vultaggio L, Parisi S, Ditto MC, Bianchi G, Fusaro E, Sebastiani GD, Govoni M, D'Angelo S, Cozzi F, Franceschini F, Guiducci S, Dagna L, Doria A, Giuggioli D, Riccieri V, Salvarani C, Iannone F, Ferri C, Matucci-Cerinic M, De Santis M, De Angelis R. Tonutti A, et al. Among authors: saracco m. J Autoimmun. 2025 Dec;157:103501. doi: 10.1016/j.jaut.2025.103501. Epub 2025 Nov 14. J Autoimmun. 2025. PMID: 41240880 Free article.
Prevalence, distribution and associations of the scleroderma capillaroscopic patterns: new insights from the Italian SPRING-SIR registry.
De Angelis R, Ferri C, Cipolletta E, Riccieri V, Di Battista M, Bajocchi G, Bellando-Randone S, Bruni C, Orlandi M, Zanframundo G, Foti R, Cuomo G, Ariani A, Rosato E, Lepri G, Girelli F, Zanatta E, Bosello SL, Cavazzana I, Ingegnoli F, De Santis M, Cacciapaglia F, Murdaca G, Abignano G, Pettiti G, Della Rossa A, Caminiti M, Iuliano AM, Ciano G, Beretta L, Bagnato G, Lubrano E, De Andres I, Idolazzi L, Saracco M, Agnes C, Campochiaro C, Fornaro M, Lumetti F, Spinella A, Cocchiara E, De Luca G, Codullo V, Visalli E, Iandoli C, Gigante A, Pellegrino G, Pigatto E, Lazzaroni MG, De Lorenzis E, Motta F, Tonutti A, Mennillo G, Pagano-Mariano G, Furini F, Vultaggio L, Parisi S, Peroni CL, Bianchi G, Fusaro E, Sebastiani GD, Govoni M, D'Angelo S, Cozzi F, Franceschini F, Guiducci S, Giuggioli D, Dagna L, Doria A, Salvarani C, Iannone F, Matucci-Cerinic M; SPRING-SIR (Systemic Sclerosis Progression Investigation group of the Italian Society for Rheumatology). De Angelis R, et al. Among authors: saracco m. Rheumatology (Oxford). 2026 Jan 8;65(1):keaf672. doi: 10.1093/rheumatology/keaf672. Rheumatology (Oxford). 2026. PMID: 41392303
Mycophenolate Mofetil Treatment Reduces the Risk of Treatment Escalation Due to Vascular Complications in Limited Cutaneous Systemic Sclerosis: Emulation of a Target Trial From the Italian Rheumatology Society SPRING Registry.
De Lorenzis E, Natalello G, De Angelis R, Verardi L, Giuggioli D, Bajocchi G, Dagna L, Bellando-Randone S, Zanframundo G, Foti R, Cacciapaglia F, Cuomo G, Ariani A, Rosato E, Lepri G, Girelli F, Riccieri V, Zanatta E, Cavazzana I, Ingegnoli F, De Santis M, Murdaca G, Abignano G, Pettiti G, Rossa AD, Caminiti M, Iuliano A, Ciano G, Beretta L, Bagnato G, Lubrano E, De Andres MI, Giollo A, Bruni C, Orlandi M, Fornaro M, Saracco M, Agnes C, Cerasuolo PG, Alonzi G, Cipolletta E, Lumetti F, Spinella A, Magnani L, Campochiaro C, De Luca G, Codullo V, Visalli E, Iandoli C, Gigante A, Pellegrino G, Pigatto E, Lazzaroni MG, Franceschini F, Generali E, Mennillo G, Barsotti S, Mariano GP, Furini F, Vultaggio L, Parisi S, Peroni CL, Bianchi G, Fusaro E, Sebastiani GD, Govoni M, D'Angelo S, Cozzi F, Conti F, Guiducci S, Doria A, Salvarani C, Iannone F, D'Agostino MA, Ferri C, Matucci Cerinic M, Bosello SL; SPRING Italian Registry Collaborators. De Lorenzis E, et al. Among authors: saracco m. Arthritis Care Res (Hoboken). 2026 Sep;78(9):1130-1139. doi: 10.1002/acr.70039. Epub 2026 Apr 17. Arthritis Care Res (Hoboken). 2026. PMID: 41466450 Free PMC article.
The clinical profile of systemic sclerosis without a 'scleroderma pattern' at nailfold capillaroscopy: results from the multicenter SPRING registry of the Italian Society of Rheumatology.
Tonutti A, De Santis M, Motta F, Bajocchi G, Giuggioli D, Bellando-Randone S, Bruni C, Zanframundo G, Foti R, Cuomo G, Ariani A, Rosato E, Lepri G, Girelli F, Zanatta E, Bosello SL, Cavazzana I, Ingegnoli F, Cacciapaglia F, Murdaca G, Abignano G, Pettiti G, Della Rossa A, Caminiti M, Iuliano AM, Ciano G, Beretta L, Bagnato G, Lubrano E, De Andres I, Idolazzi L, Saracco M, Agnes C, Campochiaro C, De Luca G, Orlandi M, Di Battista M, Nivuori M, Milazzo L, Cipolletta E, Lumetti F, Spinella A, Cocchiara E, Codullo V, Moccaldi B, Visalli E, Iandoli C, Gigante A, Pellegrino G, Pigatto E, Lazzaroni MG, De Lorenzis E, Mennillo G, Pagano-Mariano G, Furini F, Vultaggio L, Parisi S, Peroni CL, Fusaro E, Bianchi G, Sebastiani GD, Govoni M, D'Angelo S, Cozzi F, Franceschini F, Guiducci S, Riccieri V, Dagna L, Salvarani C, Iannone F, Matucci-Cerinic M, Ferri C, De Angelis R. Tonutti A, et al. Among authors: saracco m. J Transl Autoimmun. 2026 Jun 13;13:100381. doi: 10.1016/j.jtauto.2026.100381. eCollection 2026 Dec. J Transl Autoimmun. 2026. PMID: 42367240 Free PMC article.
Tocilizumab for patients with COVID-19 pneumonia. The single-arm TOCIVID-19 prospective trial.
Perrone F, Piccirillo MC, Ascierto PA, Salvarani C, Parrella R, Marata AM, Popoli P, Ferraris L, Marrocco-Trischitta MM, Ripamonti D, Binda F, Bonfanti P, Squillace N, Castelli F, Muiesan ML, Lichtner M, Calzetti C, Salerno ND, Atripaldi L, Cascella M, Costantini M, Dolci G, Facciolongo NC, Fraganza F, Massari M, Montesarchio V, Mussini C, Negri EA, Botti G, Cardone C, Gargiulo P, Gravina A, Schettino C, Arenare L, Chiodini P, Gallo C; TOCIVID-19 investigators, Italy. Perrone F, et al. J Transl Med. 2020 Oct 21;18(1):405. doi: 10.1186/s12967-020-02573-9. J Transl Med. 2020. PMID: 33087150 Free PMC article. Clinical Trial.
Correction to: Tocilizumab for patients with COVID-19 pneumonia. The single-arm TOCIVID-19 prospective trial.
Perrone F, Piccirillo MC, Ascierto PA, Salvarani C, Parrella R, Marata AM, Popoli P, Ferraris L, Marrocco-Trischitta MM, Ripamonti D, Binda F, Bonfanti P, Squillace N, Castelli F, Muiesan ML, Lichtner M, Calzetti C, Salerno ND, Atripaldi L, Cascella M, Costantini M, Dolci G, Facciolongo NC, Fraganza F, Massari M, Montesarchio V, Mussini C, Negri EA, Botti G, Cardone C, Gargiulo P, Gravina A, Schettino C, Arenare L, Chiodini P, Gallo C; TOCIVID-19 investigators, Italy. Perrone F, et al. J Transl Med. 2021 Oct 21;19(1):442. doi: 10.1186/s12967-021-03094-9. J Transl Med. 2021. PMID: 34674735 Free PMC article. No abstract available.
Clinical and serological features of triple autoantibody-negative patients with systemic sclerosis: insights from the multicentric SPRING registry of the Italian Society for Rheumatology.
Batani V, Cavazzana I, Orlandi M, De Angelis R, Campochiaro C, De Lorenzis E, Natalello G, Verardi L, Bajocchi G, Bellando-Randone S, Zanframundo G, Foti R, Cacciapaglia F, Cuomo G, Ariani A, Rosato E, Lepri G, Girelli F, Riccieri V, Zanatta E, Ingegnoli F, De Santis M, Murdaca G, Abignano G, Giorgio P, Della Rossa A, Caminiti M, Iuliano AM, Beretta L, Bagnato G, Lubrano E, De Andres I, Idolazzi L, Bruni C, Fornaro M, Saracco M, Agnes C, Cipolletta E, Lumetti F, Spinella A, De Pinto M, Magnani L, Codullo V, Visalli E, Iandoli C, Gigante A, Pellegrino G, Pigatto E, Lazzaroni MG, Franceschini F, Motta F, Tonutti A, Mennillo G, Di Battista M, Mariano GP, Furini F, Vultaggio L, Parisi S, Peroni CL, Bianchi G, Fusaro E, Sebastiani GD, Govoni M, D'Angelo S, Cozzi F, Guiducci S, Doria A, Salvarani C, Iannone F, D'Agostino MA, Bosello SL, Dagna L, Giuggioli D, Ferri C, Matucci Cerinic M, De Luca G; On the behalf of SPRING collaborators. Batani V, et al. Among authors: saracco m. RMD Open. 2026 May 13;12(2):e006495. doi: 10.1136/rmdopen-2025-006495. RMD Open. 2026. PMID: 42128529 Free PMC article.
Pulmonary Arterial Hypertension Incidence in Patients With Systemic Sclerosis Treated With Bosentan for Digital Ulcers: Evidence From the SPRING-SIR Registry.
Cacciapaglia F, De Angelis R, Ferri C, Bajocchi G, Bellando-Randone S, Bruni C, Orlandi M, Fornaro M, Cipolletta E, Zanframundo G, Foti R, Cuomo G, Ariani A, Rosato E, Lepri G, Girelli F, Zanatta E, Bosello SL, Cavazzana I, Ingegnoli F, De Santis M, Murdaca G, Abignano G, Giorgio P, Della Rossa A, Caminiti M, Iuliano A, Ciano G, Beretta L, Bagnato G, Lubrano E, De Andres I, Giollo A, Saracco M, Agnes C, Campochiaro C, Lumetti F, Spinella A, Magnani L, De Luca G, Codullo V, Visalli E, Iandoli C, Gigante A, Pellegrino G, Cozzi F, Lazzaroni MG, Generali E, Mennillo G, Barsotti S, Pagano-Mariano G, Furini F, Vultaggio L, Parisi S, Peroni CL, Bianchi G, Fusaro E, Sebastiani GD, Govoni M, D'Angelo S, Pigatto E, Franceschini F, Guiducci S, Dagna L, Doria A, Giuggioli D, Riccieri V, Salvarani C, Matucci-Cerinic M, Iannone F; Systemic Sclerosis Progression Investigation Group of the Italian Society for Rheumatology (SPRING-SIR). Cacciapaglia F, et al. Among authors: saracco m. J Rheumatol. 2025 Apr 1;52(4):375-382. doi: 10.3899/jrheum.2024-0750. J Rheumatol. 2025. PMID: 39814435
Age and onset timing of Raynaud's phenomenon and first non-Raynaud symptom as prognostic factors in systemic sclerosis: a retrospective analysis from the Italian national multicenter Systemic Sclerosis Progression INvestiGation registry of the Italian Society for Rheumatology (SPRING-SIR).
Peretti S, Bruni C, Bonomi F, De Angelis R, Bajocchi G, Giuggioli D, Orlandi M, Zanframundo G, Foti R, Visalli E, Cuomo G, Ariani A, Rosato E, Lepri G, Girelli F, Riccieri V, Zanatta E, Bosello SL, Cavazzana I, Ingegnoli F, De Santis M, Cacciapaglia F, Murdaca G, Abignano G, Pettiti G, Della Rossa A, Caminiti M, Iuliano A, Ciano G, Beretta L, Bagnato G, Lubrano E, De Andres I, Idolazzi L, Saracco M, Agnes C, Campochiaro C, De Luca G, Cipolletta E, Fornaro M, Lumetti F, Spinella A, Magnani L, Codullo V, Iandoli C, Gigante A, Pellegrino G, Pigatto E, Lazzaroni MG, De Lorenzis E, Mennillo GA, Battista MD, Pagano Mariano G, Furini F, Vultaggio L, Parisi S, Peroni CL, Bianchi G, Fusaro E, Sebastiani GD, Govoni M, D'Angelo S, Cozzi F, Franceschini F, Guiducci S, Dagna L, Doria A, Salvarani C, D'Agostino MA, Iannone F, Matucci-Cerinic M, Ferri C, Randone SB. Peretti S, et al. Among authors: saracco m. Ther Adv Musculoskelet Dis. 2026 Feb 5;18:1759720X251410243. doi: 10.1177/1759720X251410243. eCollection 2026. Ther Adv Musculoskelet Dis. 2026. PMID: 41658246 Free PMC article.
35 results