Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2009 1
2013 1
2014 6
2015 3
2016 2
2017 3
2018 1
2019 2
2020 1
2021 2
2023 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

17 results

Results by year

Filters applied: . Clear all
Page 1
[No title available]
[No authors listed] [No authors listed] PMID: 28959952 Free article.
More than a decade after a Nobel Prize was awarded for the discovery of the ubiquitin-proteasome system and clinical approval of proteasome and ubiquitin E3 ligase inhibitors, first-generation deubiquitylating enzyme (DUB) inhibitors are now approaching clinical trials. Ho …
More than a decade after a Nobel Prize was awarded for the discovery of the ubiquitin-proteasome system and clinical approval of proteasome …
[No title available]
[No authors listed] [No authors listed] PMID: 26208471
Using whole-exome sequencing, recurrent mutations have been reported in the gene coding for the ubiquitin-specific protease 8 (USP8), a protein with deubiquitinase (DUB) activity that modulates the lysosomal turnover of the EGF receptor (EGFR) and other membrane proteins. …
Using whole-exome sequencing, recurrent mutations have been reported in the gene coding for the ubiquitin-specific protease 8 (USP8), a prot …
[No title available]
[No authors listed] [No authors listed] PMID: 34604098 Free article.
[No title available]
[No authors listed] [No authors listed] PMID: 24512893 Free article.
Extension of these studies to other coronaviruses and arteriviruses led to the realization that viral protease/DUB activity is conserved in many family members. Overexpression studies revealed that viral protease/DUB activity can modulate or block activation of the …
Extension of these studies to other coronaviruses and arteriviruses led to the realization that viral protease/DUB activity is conser …
[No title available]
[No authors listed] [No authors listed] PMID: 36350544
Rpn11 is an essential metalloprotease responsible for the en bloc removal of ubiquitin chains from protein substrates that are targeted for degradation by the 26S proteasome. A unique feature of Rpn11 is that its deubiquitinase (DUB) activity is greatly stimulated by the m …
Rpn11 is an essential metalloprotease responsible for the en bloc removal of ubiquitin chains from protein substrates that are targeted for …
[No title available]
[No authors listed] [No authors listed] PMID: 19839275
We consider the current debate between bioconservatives and their chief opponents--whom we dub bioliberals--about the moral acceptability of human enhancement and the policy implications of moral debates about enhancement. ...
We consider the current debate between bioconservatives and their chief opponents--whom we dub bioliberals--about the moral acceptabi …
[No title available]
[No authors listed] [No authors listed] PMID: 33482070
The inherent demands of computational modeling guide us toward better science by forcing us to conceptually analyze, specify, and formalize intuitions that otherwise remain unexamined-what we dub open theory. Constraining our inference process through modeling enables us t …
The inherent demands of computational modeling guide us toward better science by forcing us to conceptually analyze, specify, and formalize …
[No title available]
[No authors listed] [No authors listed] PMID: 31576005 Free article.
BRCA1/BRCA2-containing complex 3 (BRCC3) is a Lysine 63-specific deubiquitinating enzyme (DUB) involved in inflammasome activity, interferon signaling, and DNA damage repair. ...
BRCA1/BRCA2-containing complex 3 (BRCC3) is a Lysine 63-specific deubiquitinating enzyme (DUB) involved in inflammasome activity, int …
[No title available]
[No authors listed] [No authors listed] PMID: 30862047 Free article.
WP1130, a partially selective deubiquitinases (DUB) inhibitor, inhibits the deubiquitinating activities of USP5, USP9X, USP14, USP37, and UCHL1. ...
WP1130, a partially selective deubiquitinases (DUB) inhibitor, inhibits the deubiquitinating activities of USP5, USP9X, USP14, USP37, …
[No title available]
[No authors listed] [No authors listed] PMID: 28029679 Free article.
Deubiquitinating enzymes (DUBs) are a large group of proteases that regulate protein degradation. The ubiquitin-specific protease 14 (USP14) is a DUB that is associated with the proteasome and negatively regulates proteasome activity. ...These data not only highlight the s …
Deubiquitinating enzymes (DUBs) are a large group of proteases that regulate protein degradation. The ubiquitin-specific protease 14 (USP14) …
17 results