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Year Number of Results
2004 1
2005 1
2006 1
2016 1
2017 3
2018 2
2019 2
2020 3
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3-Hydroxypyrimidine-2,4-dione-5-N-benzylcarboxamides Potently Inhibit HIV-1 Integrase and RNase H.
Wu B, Tang J, Wilson DJ, Huber AD, Casey MC, Ji J, Kankanala J, Xie J, Sarafianos SG, Wang Z. Wu B, et al. Among authors: Casey MC. J Med Chem. 2016 Jul 14;59(13):6136-48. doi: 10.1021/acs.jmedchem.6b00040. Epub 2016 Jun 17. J Med Chem. 2016. PMID: 27283261 Free PMC article.
6-Biphenylmethyl-3-hydroxypyrimidine-2,4-diones potently and selectively inhibited HIV reverse transcriptase-associated RNase H.
Wang L, Tang J, Huber AD, Casey MC, Kirby KA, Wilson DJ, Kankanala J, Parniak MA, Sarafianos SG, Wang Z. Wang L, et al. Among authors: Casey MC. Eur J Med Chem. 2018 Aug 5;156:680-691. doi: 10.1016/j.ejmech.2018.07.035. Epub 2018 Jul 17. Eur J Med Chem. 2018. PMID: 30031978 Free PMC article.
Double-Winged 3-Hydroxypyrimidine-2,4-diones: Potent and Selective Inhibition against HIV-1 RNase H with Significant Antiviral Activity.
Vernekar SKV, Tang J, Wu B, Huber AD, Casey MC, Myshakina N, Wilson DJ, Kankanala J, Kirby KA, Parniak MA, Sarafianos SG, Wang Z. Vernekar SKV, et al. Among authors: Casey MC. J Med Chem. 2017 Jun 22;60(12):5045-5056. doi: 10.1021/acs.jmedchem.7b00440. Epub 2017 May 31. J Med Chem. 2017. PMID: 28525279 Free PMC article.
6-Arylthio-3-hydroxypyrimidine-2,4-diones potently inhibited HIV reverse transcriptase-associated RNase H with antiviral activity.
Wang L, Tang J, Huber AD, Casey MC, Kirby KA, Wilson DJ, Kankanala J, Xie J, Parniak MA, Sarafianos SG, Wang Z. Wang L, et al. Among authors: Casey MC. Eur J Med Chem. 2018 Aug 5;156:652-665. doi: 10.1016/j.ejmech.2018.07.039. Epub 2018 Jul 17. Eur J Med Chem. 2018. PMID: 30031976 Free PMC article.
6-Cyclohexylmethyl-3-hydroxypyrimidine-2,4-dione as an inhibitor scaffold of HIV reverase transcriptase: Impacts of the 3-OH on inhibiting RNase H and polymerase.
Tang J, Kirby KA, Huber AD, Casey MC, Ji J, Wilson DJ, Sarafianos SG, Wang Z. Tang J, et al. Among authors: Casey MC. Eur J Med Chem. 2017 Mar 10;128:168-179. doi: 10.1016/j.ejmech.2017.01.041. Epub 2017 Jan 30. Eur J Med Chem. 2017. PMID: 28182989 Free PMC article.
Pharmacophore-based design of novel 3-hydroxypyrimidine-2,4-dione subtypes as inhibitors of HIV reverse transcriptase-associated RNase H: Tolerance of a nonflexible linker.
Tang J, Do HT, Huber AD, Casey MC, Kirby KA, Wilson DJ, Kankanala J, Parniak MA, Sarafianos SG, Wang Z. Tang J, et al. Among authors: Casey MC. Eur J Med Chem. 2019 Mar 15;166:390-399. doi: 10.1016/j.ejmech.2019.01.081. Epub 2019 Feb 2. Eur J Med Chem. 2019. PMID: 30739822 Free PMC article.
Effects of Moloney Leukemia Virus 10 Protein on Hepatitis B Virus Infection and Viral Replication.
Puray-Chavez MN, Farghali MH, Yapo V, Huber AD, Liu D, Ndongwe TP, Casey MC, Laughlin TG, Hannink M, Tedbury PR, Sarafianos SG. Puray-Chavez MN, et al. Among authors: Casey MC. Viruses. 2019 Jul 17;11(7):651. doi: 10.3390/v11070651. Viruses. 2019. PMID: 31319455 Free PMC article.
Design, synthesis and biological evaluations of N-Hydroxy thienopyrimidine-2,4-diones as inhibitors of HIV reverse transcriptase-associated RNase H.
Kankanala J, Kirby KA, Huber AD, Casey MC, Wilson DJ, Sarafianos SG, Wang Z. Kankanala J, et al. Among authors: Casey MC. Eur J Med Chem. 2017 Dec 1;141:149-161. doi: 10.1016/j.ejmech.2017.09.054. Epub 2017 Sep 28. Eur J Med Chem. 2017. PMID: 29031062 Free PMC article.
Chemical profiling of HIV-1 capsid-targeting antiviral PF74.
Wang L, Casey MC, Vernekar SKV, Do HT, Sahani RL, Kirby KA, Du H, Hachiya A, Zhang H, Tedbury PR, Xie J, Sarafianos SG, Wang Z. Wang L, et al. Among authors: Casey MC. Eur J Med Chem. 2020 Aug 15;200:112427. doi: 10.1016/j.ejmech.2020.112427. Epub 2020 May 12. Eur J Med Chem. 2020. PMID: 32438252
Toward Structurally Novel and Metabolically Stable HIV-1 Capsid-Targeting Small Molecules.
Vernekar SKV, Sahani RL, Casey MC, Kankanala J, Wang L, Kirby KA, Du H, Zhang H, Tedbury PR, Xie J, Sarafianos SG, Wang Z. Vernekar SKV, et al. Among authors: Casey MC. Viruses. 2020 Apr 16;12(4):452. doi: 10.3390/v12040452. Viruses. 2020. PMID: 32316297 Free PMC article.
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