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2013 1
2014 1
2016 1
2017 2
2020 0
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Page 1
Proteolysis of mature HIV-1 p6 Gag protein by the insulin-degrading enzyme (IDE) regulates virus replication in an Env-dependent manner.
Hahn F, Schmalen A, Setz C, Friedrich M, Schlößer S, Kölle J, Spranger R, Rauch P, Fraedrich K, Reif T, Karius-Fischer J, Balasubramanyam A, Henklein P, Fossen T, Schubert U. Hahn F, et al. Among authors: friedrich m. PLoS One. 2017 Apr 7;12(4):e0174254. doi: 10.1371/journal.pone.0174254. eCollection 2017. PLoS One. 2017. PMID: 28388673 Free PMC article. Clinical Trial.
Inhibitors of Deubiquitinating Enzymes Block HIV-1 Replication and Augment the Presentation of Gag-Derived MHC-I Epitopes.
Setz C, Friedrich M, Rauch P, Fraedrich K, Matthaei A, Traxdorf M, Schubert U. Setz C, et al. Among authors: friedrich m. Viruses. 2017 Aug 12;9(8):222. doi: 10.3390/v9080222. Viruses. 2017. PMID: 28805676 Free PMC article.
Glutamic Acid Residues in HIV-1 p6 Regulate Virus Budding and Membrane Association of Gag.
Friedrich M, Setz C, Hahn F, Matthaei A, Fraedrich K, Rauch P, Henklein P, Traxdorf M, Fossen T, Schubert U. Friedrich M, et al. Viruses. 2016 Apr 25;8(4):117. doi: 10.3390/v8040117. Viruses. 2016. PMID: 27120610 Free PMC article.
Just one position-independent lysine residue can direct MelanA into proteasomal degradation following N-terminal fusion of ubiquitin.
Setz C, Friedrich M, Hahn S, Dörrie J, Schaft N, Schuler G, Schubert U. Setz C, et al. Among authors: friedrich m. PLoS One. 2013;8(2):e55567. doi: 10.1371/journal.pone.0055567. Epub 2013 Feb 5. PLoS One. 2013. PMID: 23393593 Free PMC article.
Mutation of the highly conserved Ser-40 of the HIV-1 p6 gag protein to Phe causes the formation of a hydrophobic patch, enhances membrane association, and polyubiquitination of Gag.
Hahn F, Setz C, Friedrich M, Rauch P, Solbak SM, Frøystein NA, Henklein P, Votteler J, Fossen T, Schubert U. Hahn F, et al. Among authors: friedrich m. Viruses. 2014 Oct 2;6(10):3738-65. doi: 10.3390/v6103738. Viruses. 2014. PMID: 25279819 Free PMC article.