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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1929 1
1947 1
1948 2
1951 2
1952 4
1953 2
1956 1
1957 3
1958 2
1959 1
1961 2
1963 3
1964 5
1965 3
1966 4
1967 6
1968 1
1969 2
1970 5
1971 4
1972 4
1973 2
1974 1
1975 8
1976 8
1977 9
1978 8
1979 3
1980 6
1981 10
1982 9
1983 5
1984 13
1985 8
1986 19
1987 22
1988 17
1989 26
1990 23
1991 32
1992 25
1993 23
1994 26
1995 30
1996 47
1997 41
1998 44
1999 54
2000 76
2001 69
2002 96
2003 98
2004 102
2005 104
2006 104
2007 119
2008 136
2009 140
2010 160
2011 196
2012 242
2013 274
2014 310
2015 349
2016 415
2017 406
2018 477
2019 513
2020 627
2021 217
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5,201 results
Results by year
Filters applied: . Clear all The following term was not found in PubMed: Wannewitz
Page 1
Maternal IL-17A in autism.
Wong H, Hoeffer C. Wong H, et al. Exp Neurol. 2018 Jan;299(Pt A):228-240. doi: 10.1016/j.expneurol.2017.04.010. Epub 2017 Apr 25. Exp Neurol. 2018. PMID: 28455196 Free PMC article. Review.
This raises the question of how MIA exposure can lead to ASD in susceptible individuals. Recent evidence points to a potential inflammation pathway linking MIA-associated ASD with the activity of T helper 17 (Th17) lymphocytes and their effector cytokine interleukin …
This raises the question of how MIA exposure can lead to ASD in susceptible individuals. Recent evidence points to a potential inflam …
Evolution of a maternal immune activation (mIA) model in rats: Early developmental effects.
Murray KN, Edye ME, Manca M, Vernon AC, Oladipo JM, Fasolino V, Harte MK, Mason V, Grayson B, McHugh PC, Knuesel I, Prinssen EP, Hager R, Neill JC. Murray KN, et al. Brain Behav Immun. 2019 Jan;75:48-59. doi: 10.1016/j.bbi.2018.09.005. Epub 2018 Sep 12. Brain Behav Immun. 2019. PMID: 30218784
Here, we optimise a mIA model in rats, aiming to address certain limitations of current work in this field. Specifically, the lack of clear evidence for methodology chosen, identification of successful induction of mIA in the dams and investigation of male offspring …
Here, we optimise a mIA model in rats, aiming to address certain limitations of current work in this field. Specifically, the lack of …
Modeling Autism-Related Disorders in Mice with Maternal Immune Activation (MIA).
Lammert CR, Lukens JR. Lammert CR, et al. Methods Mol Biol. 2019;1960:227-236. doi: 10.1007/978-1-4939-9167-9_20. Methods Mol Biol. 2019. PMID: 30798536 Free PMC article.
It has been shown that MIA-induced ASD can be modeled by treating pregnant mice with the viral mimetic polyinosinic-polycytidylic acid (PolyI:C) during key neurodevelopmental time points. ...Here we describe best practices for how the PolyI:C model of MIA can be use …
It has been shown that MIA-induced ASD can be modeled by treating pregnant mice with the viral mimetic polyinosinic-polycytidylic aci …
Maternal immune activation alters fetal brain development through interleukin-6.
Smith SE, Li J, Garbett K, Mirnics K, Patterson PH. Smith SE, et al. J Neurosci. 2007 Oct 3;27(40):10695-702. doi: 10.1523/JNEUROSCI.2178-07.2007. J Neurosci. 2007. PMID: 17913903 Free PMC article.
However, the mechanism by which MIA causes long-term behavioral deficits in the offspring is unknown. ...Finally, MIA in IL-6 knock-out mice does not result in several of the behavioral changes seen in the offspring of wild-type mice after MIA. ...
However, the mechanism by which MIA causes long-term behavioral deficits in the offspring is unknown. ...Finally, MIA in IL-6 …
The Monoiodoacetate Model of Osteoarthritis Pain in the Mouse.
Pitcher T, Sousa-Valente J, Malcangio M. Pitcher T, et al. J Vis Exp. 2016 May 16;(111):53746. doi: 10.3791/53746. J Vis Exp. 2016. PMID: 27214709 Free PMC article.
Currently available models of OA in rodents include surgical and chemical interventions into one knee joint. The monoiodoacetate (MIA) model has become a standard for modelling joint disruption in OA in both rats and mice. ...These behavioral changes resemble some of the s …
Currently available models of OA in rodents include surgical and chemical interventions into one knee joint. The monoiodoacetate (MIA
The clinical significance of MIA gene in tumorigenesis of lung cancer.
Gu QH, Li D, Xie ZH, Shen QB. Gu QH, et al. Neoplasma. 2020 May;67(3):660-667. doi: 10.4149/neo_2020_190511N422. Epub 2020 Jan 27. Neoplasma. 2020. PMID: 31986890
MIA was reported as an oncogene in several cancers. But its role in lung cancer was unknown. ...Mechanically, the anti-apoptosis marker Bcl-2 was increased and pro-apoptosis marker Bax was decreased after MIA was overexpressed in A549 cells, and vice versa. The leve
MIA was reported as an oncogene in several cancers. But its role in lung cancer was unknown. ...Mechanically, the anti-apoptosis mark
The placental interleukin-6 signaling controls fetal brain development and behavior.
Wu WL, Hsiao EY, Yan Z, Mazmanian SK, Patterson PH. Wu WL, et al. Brain Behav Immun. 2017 May;62:11-23. doi: 10.1016/j.bbi.2016.11.007. Epub 2016 Nov 9. Brain Behav Immun. 2017. PMID: 27838335 Free PMC article.
Epidemiological studies show that maternal immune activation (MIA) during pregnancy is a risk factor for autism. However, mechanisms for how MIA affects brain development and behaviors in offspring remain poorly described. ...We reveal that MIA results in acu …
Epidemiological studies show that maternal immune activation (MIA) during pregnancy is a risk factor for autism. However, mechanisms …
Maternal immune activation in neurodevelopmental disorders.
Solek CM, Farooqi N, Verly M, Lim TK, Ruthazer ES. Solek CM, et al. Dev Dyn. 2018 Apr;247(4):588-619. doi: 10.1002/dvdy.24612. Epub 2017 Dec 23. Dev Dyn. 2018. PMID: 29226543 Free article. Review.
The mechanisms through which MIA increases the risk of neurodevelopmental disorders have become a subject of intensive research. This review aims to describe how dysregulation of microglial function and immune mechanisms may link MIA and neurodevelopmental pathologi …
The mechanisms through which MIA increases the risk of neurodevelopmental disorders have become a subject of intensive research. This …
Neurodevelopmental Resilience and Susceptibility to Maternal Immune Activation.
Meyer U. Meyer U. Trends Neurosci. 2019 Nov;42(11):793-806. doi: 10.1016/j.tins.2019.08.001. Epub 2019 Sep 4. Trends Neurosci. 2019. PMID: 31493924 Review.
Maternal immune activation (MIA), be it triggered by infectious or noninfectious stimuli, is implicated in various psychiatric and neurological disorders with developmental etiologies. ...This review provides a synopsis of the plausible sources that account for the heterog …
Maternal immune activation (MIA), be it triggered by infectious or noninfectious stimuli, is implicated in various psychiatric and ne …
Monocytic Infiltrates Contribute to Autistic-like Behaviors in a Two-Hit Model of Neurodevelopmental Defects.
Chen HR, Chen CW, Mandhani N, Short-Miller JC, Smucker MR, Sun YY, Kuan CY. Chen HR, et al. J Neurosci. 2020 Dec 2;40(49):9386-9400. doi: 10.1523/JNEUROSCI.1171-20.2020. Epub 2020 Oct 30. J Neurosci. 2020. PMID: 33127853
Herein we compared the effects of MIA (injection of poly[I:C] to dam at gestational day 12.5), HI at postnatal day 10, and the combined MIA/HI insult in murine offspring of both sexes. ...Conversely, HI neither provoked autistic-like behaviors nor concealed them in …
Herein we compared the effects of MIA (injection of poly[I:C] to dam at gestational day 12.5), HI at postnatal day 10, and the combin …
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