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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2002 4
2003 2
2004 2
2005 5
2006 5
2007 3
2008 7
2009 14
2010 11
2011 15
2012 10
2013 10
2014 8
2015 11
2016 14
2017 13
2018 17
2019 15
2020 19
2021 13
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179 results
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Page 1
Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders.
Steinebach C, Ng YLD, Sosič I, Lee CS, Chen S, Lindner S, Vu LP, Bricelj A, Haschemi R, Monschke M, Steinwarz E, Wagner KG, Bendas G, Luo J, Gütschow M, Krönke J. Steinebach C, et al. Among authors: gutschow m. Chem Sci. 2020 Mar 4;11(13):3474-3486. doi: 10.1039/d0sc00167h. eCollection 2020 Apr 7. Chem Sci. 2020. PMID: 33133483 Free PMC article.
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7.
Gütschow M, Eynde JJV, Jampilek J, Kang C, Mangoni AA, Fossa P, Karaman R, Trabocchi A, Scott PJH, Reynisson J, Rapposelli S, Galdiero S, Winum JY, Brullo C, Prokai-Tatrai K, Sharma AK, Schapira M, Azuma YT, Cerchia L, Spetea M, Torri G, Collina S, Geronikaki A, García-Sosa AT, Vasconcelos MH, Sousa ME, Kosalec I, Tuccinardi T, Duarte IF, Salvador JAR, Bertinaria M, Pellecchia M, Amato J, Rastelli G, Gomes PAC, Guedes RC, Sabatier JM, Estévez-Braun A, Pagano B, Mangani S, Ragno R, Kokotos G, Brindisi M, González FV, Borges F, Miloso M, Rautio J, Muñoz-Torrero D. Gütschow M, et al. Molecules. 2020 Jun 28;25(13):2968. doi: 10.3390/molecules25132968. Molecules. 2020. PMID: 32605268 Free PMC article.
Can Cysteine Protease Cross-Class Inhibitors Achieve Selectivity?
Cianni L, Feldmann CW, Gilberg E, Gütschow M, Juliano L, Leitão A, Bajorath J, Montanari CA. Cianni L, et al. Among authors: gutschow m. J Med Chem. 2019 Dec 12;62(23):10497-10525. doi: 10.1021/acs.jmedchem.9b00683. Epub 2019 Aug 15. J Med Chem. 2019. PMID: 31361135 Review.
PROTAC-mediated crosstalk between E3 ligases.
Steinebach C , Kehm H , Lindner S , Vu LP , Köpff S , López Mármol Á , Weiler C , Wagner KG , Reichenzeller M , Krönke J , Gütschow M . Steinebach C , et al. Among authors: gutschow m. Chem Commun (Camb). 2019 Feb 5;55(12):1821-1824. doi: 10.1039/c8cc09541h. Chem Commun (Camb). 2019. PMID: 30672516
Allosteric modulation of caspases.
Häcker HG, Sisay MT, Gütschow M. Häcker HG, et al. Among authors: gutschow m. Pharmacol Ther. 2011 Nov;132(2):180-95. doi: 10.1016/j.pharmthera.2011.07.003. Epub 2011 Jul 23. Pharmacol Ther. 2011. PMID: 21807025 Review.
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