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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 4
2003 2
2004 2
2005 5
2006 5
2007 3
2008 7
2009 14
2010 11
2011 15
2012 10
2013 10
2014 8
2015 11
2016 13
2017 13
2018 17
2019 15
2020 19
2021 3
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169 results
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Page 1
PROTAC-mediated crosstalk between E3 ligases.
Steinebach C , Kehm H , Lindner S , Vu LP , Köpff S , López Mármol Á , Weiler C , Wagner KG , Reichenzeller M , Krönke J , Gütschow M . Steinebach C , et al. Among authors: gutschow m. Chem Commun (Camb). 2019 Feb 5;55(12):1821-1824. doi: 10.1039/c8cc09541h. Chem Commun (Camb). 2019. PMID: 30672516
Homo-PROTACs for the Chemical Knockdown of Cereblon.
Steinebach C, Lindner S, Udeshi ND, Mani DC, Kehm H, Köpff S, Carr SA, Gütschow M, Krönke J. Steinebach C, et al. Among authors: gutschow m. ACS Chem Biol. 2018 Sep 21;13(9):2771-2782. doi: 10.1021/acschembio.8b00693. Epub 2018 Sep 5. ACS Chem Biol. 2018. PMID: 30118587
Lenalidomide and pomalidomide potently interfere with induction of myeloid-derived suppressor cells in multiple myeloma.
Kuwahara-Ota S, Shimura Y, Steinebach C, Isa R, Yamaguchi J, Nishiyama D, Fujibayashi Y, Takimoto-Shimomura T, Mizuno Y, Matsumura-Kimoto Y, Tsukamoto T, Chinen Y, Kobayashi T, Horiike S, Taniwaki M, Gütschow M, Kuroda J. Kuwahara-Ota S, et al. Among authors: gutschow m. Br J Haematol. 2020 Jun 19. doi: 10.1111/bjh.16881. Online ahead of print. Br J Haematol. 2020. PMID: 32558939
Cell-permeable high-affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors.
Kuschak M, Namasivayam V, Rafehi M, Voss JH, Garg J, Schlegel JG, Abdelrahman A, Kehraus S, Reher R, Küppers J, Sylvester K, Hinz S, Matthey M, Wenzel D, Fleischmann BK, Pfeifer A, Inoue A, Gütschow M, König GM, Müller CE. Kuschak M, et al. Among authors: gutschow m. Br J Pharmacol. 2020 Apr;177(8):1898-1916. doi: 10.1111/bph.14960. Epub 2020 Feb 11. Br J Pharmacol. 2020. PMID: 31881095 Free PMC article.
Glutamine-induced signaling pathways via amino acid receptors in enteroendocrine L cell lines.
Nakamura T, Harada K, Kamiya T, Takizawa M, Küppers J, Nakajima K, Gütschow M, Kitaguchi T, Ohta K, Kato T, Tsuboi T. Nakamura T, et al. Among authors: gutschow m. J Mol Endocrinol. 2020 Apr;64(3):133-143. doi: 10.1530/JME-19-0260. J Mol Endocrinol. 2020. PMID: 31940281
Can Cysteine Protease Cross-Class Inhibitors Achieve Selectivity?
Cianni L, Feldmann CW, Gilberg E, Gütschow M, Juliano L, Leitão A, Bajorath J, Montanari CA. Cianni L, et al. Among authors: gutschow m. J Med Chem. 2019 Dec 12;62(23):10497-10525. doi: 10.1021/acs.jmedchem.9b00683. Epub 2019 Aug 15. J Med Chem. 2019. PMID: 31361135 Review.
A MedChem toolbox for cereblon-directed PROTACs.
Steinebach C, Sosič I, Lindner S, Bricelj A, Kohl F, Ng YLD, Monschke M, Wagner KG, Krönke J, Gütschow M. Steinebach C, et al. Among authors: gutschow m. Medchemcomm. 2019 May 28;10(6):1037-1041. doi: 10.1039/c9md00185a. eCollection 2019 Jun 1. Medchemcomm. 2019. PMID: 31304001 Free PMC article.
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6.
Vanden Eynde JJ, Mangoni AA, Rautio J, Leprince J, Azuma YT, García-Sosa AT, Hulme C, Jampilek J, Karaman R, Li W, Gomes PAC, Hadjipavlou-Litina D, Capasso R, Geronikaki A, Cerchia L, Sabatier JM, Ragno R, Tuccinardi T, Trabocchi A, Winum JY, Luque FJ, Prokai-Tatrai K, Spetea M, Gütschow M, Kosalec I, Guillou C, Vasconcelos MH, Kokotos G, Rastelli G, de Sousa ME, Manera C, Gemma S, Mangani S, Siciliano C, Galdiero S, Liu H, Scott PJH, de Los Ríos C, Agrofoglio LA, Collina S, Guedes RC, Muñoz-Torrero D. Vanden Eynde JJ, et al. Among authors: gutschow m. Molecules. 2019 Dec 28;25(1):119. doi: 10.3390/molecules25010119. Molecules. 2019. PMID: 31905602 Free PMC article.
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-5.
Mangoni AA, Eynde JJV, Jampilek J, Hadjipavlou-Litina D, Liu H, Reynisson J, Sousa ME, Gomes PAC, Prokai-Tatrai K, Tuccinardi T, Sabatier JM, Luque FJ, Rautio J, Karaman R, Vasconcelos MH, Gemma S, Galdiero S, Hulme C, Collina S, Gütschow M, Kokotos G, Siciliano C, Capasso R, Agrofoglio LA, Ragno R, Muñoz-Torrero D. Mangoni AA, et al. Among authors: gutschow m. Molecules. 2019 Jun 30;24(13):2415. doi: 10.3390/molecules24132415. Molecules. 2019. PMID: 31262039 Free PMC article.
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7.
Gütschow M, Eynde JJV, Jampilek J, Kang C, Mangoni AA, Fossa P, Karaman R, Trabocchi A, Scott PJH, Reynisson J, Rapposelli S, Galdiero S, Winum JY, Brullo C, Prokai-Tatrai K, Sharma AK, Schapira M, Azuma YT, Cerchia L, Spetea M, Torri G, Collina S, Geronikaki A, García-Sosa AT, Vasconcelos MH, Sousa ME, Kosalec I, Tuccinardi T, Duarte IF, Salvador JAR, Bertinaria M, Pellecchia M, Amato J, Rastelli G, Gomes PAC, Guedes RC, Sabatier JM, Estévez-Braun A, Pagano B, Mangani S, Ragno R, Kokotos G, Brindisi M, González FV, Borges F, Miloso M, Rautio J, Muñoz-Torrero D. Gütschow M, et al. Molecules. 2020 Jun 28;25(13):2968. doi: 10.3390/molecules25132968. Molecules. 2020. PMID: 32605268 Free PMC article.
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